ES385518A1 - Procedimiento para la obtencion de compuestos de 4-amino- spiro (ciclohexan-1,9'-tioxanteno). - Google Patents
Procedimiento para la obtencion de compuestos de 4-amino- spiro (ciclohexan-1,9'-tioxanteno).Info
- Publication number
- ES385518A1 ES385518A1 ES385518A ES385518A ES385518A1 ES 385518 A1 ES385518 A1 ES 385518A1 ES 385518 A ES385518 A ES 385518A ES 385518 A ES385518 A ES 385518A ES 385518 A1 ES385518 A1 ES 385518A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- compound
- formula
- treated
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000003003 spiro group Chemical group 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 229910052801 chlorine Inorganic materials 0.000 abstract 3
- 239000000460 chlorine Substances 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229940100198 alkylating agent Drugs 0.000 abstract 1
- 239000002168 alkylating agent Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 150000002081 enamines Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000002443 hydroxylamines Chemical class 0.000 abstract 1
- 238000003402 intramolecular cyclocondensation reaction Methods 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000002902 organometallic compounds Chemical class 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- -1 pyrrolidino, piperidino Chemical group 0.000 abstract 1
- 125000000467 secondary amino group Chemical class [H]N([*:1])[*:2] 0.000 abstract 1
- DALBSHCZBQCZKU-UHFFFAOYSA-N spiro[cyclohexane-4,9'-thioxanthene]-1-amine Chemical class NC1CCC2(CC1)C1=CC=CC=C1SC=1C=CC=CC12 DALBSHCZBQCZKU-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19691957490 DE1957490A1 (de) | 1969-11-15 | 1969-11-15 | 4-Amino-spiro [cyclohexan-1,9'-thioxanthen]-Verbindungen sowie Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES385518A1 true ES385518A1 (es) | 1973-08-16 |
Family
ID=5751176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES385518A Expired ES385518A1 (es) | 1969-11-15 | 1970-11-13 | Procedimiento para la obtencion de compuestos de 4-amino- spiro (ciclohexan-1,9'-tioxanteno). |
Country Status (16)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1434486A (en) * | 1974-02-04 | 1976-05-05 | Ici Ltd | Thioxanthene derivatives |
| GB1447583A (en) * | 1974-02-04 | 1976-08-25 | Ici Ltd | Xanthene derivatives |
| JPS54112874A (en) * | 1978-02-23 | 1979-09-04 | Yoshitomi Pharmaceut Ind Ltd | Thioxanthene derivative |
| AU3632297A (en) | 1996-08-26 | 1998-03-19 | Pfizer Inc. | Spirocyclic dopamine receptor subtype ligands |
| US7014925B2 (en) * | 2003-04-29 | 2006-03-21 | Canon Kabushiki Kaisha | Heterogeneous spiro compounds in organic light emitting device elements |
| US20080207738A1 (en) * | 2007-02-28 | 2008-08-28 | Cancure Laboratories, Llc | Drug combinations to treat drug resistant tumors |
-
0
- BE BE758919D patent/BE758919A/xx unknown
-
1969
- 1969-11-15 DE DE19691957490 patent/DE1957490A1/de active Pending
-
1970
- 1970-10-08 GB GB1289209D patent/GB1289209A/en not_active Expired
- 1970-10-12 ZA ZA706933A patent/ZA706933B/xx unknown
- 1970-10-13 IL IL35443A patent/IL35443A/en unknown
- 1970-10-23 NL NL7015562A patent/NL7015562A/xx unknown
- 1970-10-23 DK DK539570AA patent/DK126044B/da unknown
- 1970-10-25 CS CS727335A patent/CS162734B2/cs unknown
- 1970-10-25 CS CS727334A patent/CS162733B2/cs unknown
- 1970-10-25 CS CS7199A patent/CS162732B2/cs unknown
- 1970-10-25 CS CS727337A patent/CS162736B2/cs unknown
- 1970-10-25 CS CS727336A patent/CS162735B2/cs unknown
- 1970-11-03 PL PL1970144225A patent/PL83016B1/pl unknown
- 1970-11-04 SE SE7014892A patent/SE370400B/xx unknown
- 1970-11-10 FR FR7040459A patent/FR2073359B1/fr not_active Expired
- 1970-11-12 CA CA097,969A patent/CA954133A/en not_active Expired
- 1970-11-13 AT AT530471A patent/AT300801B/de not_active IP Right Cessation
- 1970-11-13 CH CH469673A patent/CH565173A5/xx not_active IP Right Cessation
- 1970-11-13 US US00089489A patent/US3721672A/en not_active Expired - Lifetime
- 1970-11-13 CH CH469873A patent/CH561201A5/xx not_active IP Right Cessation
- 1970-11-13 CH CH1681770A patent/CH564008A5/xx not_active IP Right Cessation
- 1970-11-13 AT AT530571A patent/AT300802B/de not_active IP Right Cessation
- 1970-11-13 CH CH469773A patent/CH561200A5/xx not_active IP Right Cessation
- 1970-11-13 AT AT530671A patent/AT300803B/de not_active IP Right Cessation
- 1970-11-13 CH CH469573A patent/CH561199A5/xx not_active IP Right Cessation
- 1970-11-13 ES ES385518A patent/ES385518A1/es not_active Expired
- 1970-11-13 AT AT530371A patent/AT298488B/de active
- 1970-11-13 AT AT1025370A patent/AT300799B/de not_active IP Right Cessation
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