GB1288738A - - Google Patents
Info
- Publication number
- GB1288738A GB1288738A GB1288738DA GB1288738A GB 1288738 A GB1288738 A GB 1288738A GB 1288738D A GB1288738D A GB 1288738DA GB 1288738 A GB1288738 A GB 1288738A
- Authority
- GB
- United Kingdom
- Prior art keywords
- picolyl
- ethyl
- phenylacetamide
- formyl
- pyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LSBDFXRDZJMBSC-UHFFFAOYSA-N 2-phenylacetamide Chemical compound NC(=O)CC1=CC=CC=C1 LSBDFXRDZJMBSC-UHFFFAOYSA-N 0.000 abstract 2
- BOSZZJXMJIHZDP-UHFFFAOYSA-N n-ethyl-2-phenyl-n-(pyridin-4-ylmethyl)acetamide Chemical compound C=1C=CC=CC=1CC(=O)N(CC)CC1=CC=NC=C1 BOSZZJXMJIHZDP-UHFFFAOYSA-N 0.000 abstract 2
- LSIXBBPOJBJQHN-UHFFFAOYSA-N 2,3-Dimethylbicyclo[2.2.1]hept-2-ene Chemical compound C1CC2C(C)=C(C)C1C2 LSIXBBPOJBJQHN-UHFFFAOYSA-N 0.000 abstract 1
- VMZCDNSFRSVYKQ-UHFFFAOYSA-N 2-phenylacetyl chloride Chemical compound ClC(=O)CC1=CC=CC=C1 VMZCDNSFRSVYKQ-UHFFFAOYSA-N 0.000 abstract 1
- JNZPMUYXFLEHBT-UHFFFAOYSA-N N-ethyl-2-(2-formylphenyl)-N-(pyridin-4-ylmethyl)acetamide Chemical compound C(C)N(C(CC1=C(C=CC=C1)C=O)=O)CC1=CC=NC=C1 JNZPMUYXFLEHBT-UHFFFAOYSA-N 0.000 abstract 1
- BGDKAVGWHJFAGW-UHFFFAOYSA-N Tropicamide Chemical compound C=1C=CC=CC=1C(CO)C(=O)N(CC)CC1=CC=NC=C1 BGDKAVGWHJFAGW-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- BGUWFUQJCDRPTL-UHFFFAOYSA-N pyridine-4-carbaldehyde Chemical compound O=CC1=CC=NC=C1 BGUWFUQJCDRPTL-UHFFFAOYSA-N 0.000 abstract 1
- 150000003222 pyridines Chemical class 0.000 abstract 1
- 238000006722 reduction reaction Methods 0.000 abstract 1
- 238000006268 reductive amination reaction Methods 0.000 abstract 1
- -1 γ - picolyl Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP45002755A JPS4815947B1 (cg-RX-API-DMAC10.html) | 1970-01-09 | 1970-01-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1288738A true GB1288738A (cg-RX-API-DMAC10.html) | 1972-09-13 |
Family
ID=11538146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1288738D Expired GB1288738A (cg-RX-API-DMAC10.html) | 1970-01-09 | 1970-12-08 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3741975A (cg-RX-API-DMAC10.html) |
| JP (1) | JPS4815947B1 (cg-RX-API-DMAC10.html) |
| CH (1) | CH560684A5 (cg-RX-API-DMAC10.html) |
| FR (1) | FR2075530A5 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1288738A (cg-RX-API-DMAC10.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109444312A (zh) * | 2018-10-19 | 2019-03-08 | 重庆市食品药品检验检测研究院 | 一种托吡卡胺杂质及用途 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103387534B (zh) * | 2012-05-09 | 2015-02-18 | 北大方正集团有限公司 | 一种拆分托吡卡胺外消旋体的方法 |
| CN103159672A (zh) * | 2012-07-16 | 2013-06-19 | 湖南尔文生物科技有限公司 | 一种托品酰胺的制备方法 |
| CN117362220A (zh) * | 2023-09-27 | 2024-01-09 | 南京法恩化学有限公司 | 一种托吡卡胺的制备方法 |
-
1970
- 1970-01-09 JP JP45002755A patent/JPS4815947B1/ja active Pending
- 1970-12-08 GB GB1288738D patent/GB1288738A/en not_active Expired
- 1970-12-11 US US00097374A patent/US3741975A/en not_active Expired - Lifetime
- 1970-12-17 CH CH1875770A patent/CH560684A5/xx not_active IP Right Cessation
-
1971
- 1971-01-07 FR FR7101049A patent/FR2075530A5/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109444312A (zh) * | 2018-10-19 | 2019-03-08 | 重庆市食品药品检验检测研究院 | 一种托吡卡胺杂质及用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2100499B2 (de) | 1976-05-13 |
| FR2075530A5 (cg-RX-API-DMAC10.html) | 1971-10-08 |
| JPS4815947B1 (cg-RX-API-DMAC10.html) | 1973-05-18 |
| CH560684A5 (cg-RX-API-DMAC10.html) | 1975-04-15 |
| DE2100499A1 (de) | 1971-07-22 |
| US3741975A (en) | 1973-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] |