GB1281549A - Thiazacyclic amino compounds and process for their manufacture - Google Patents
Thiazacyclic amino compounds and process for their manufactureInfo
- Publication number
- GB1281549A GB1281549A GB57065/71A GB5706571A GB1281549A GB 1281549 A GB1281549 A GB 1281549A GB 57065/71 A GB57065/71 A GB 57065/71A GB 5706571 A GB5706571 A GB 5706571A GB 1281549 A GB1281549 A GB 1281549A
- Authority
- GB
- United Kingdom
- Prior art keywords
- heptan
- formula
- azabicyclo
- penicillin
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 title 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Natural products N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- WSHJJCPTKWSMRR-UHFFFAOYSA-N 4-thia-1-azabicyclo[3.2.0]heptan-7-one Chemical class S1CCN2C(=O)CC21 WSHJJCPTKWSMRR-UHFFFAOYSA-N 0.000 abstract 2
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 2
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 2
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229940056360 penicillin g Drugs 0.000 abstract 2
- -1 penicillin-V triethylammonium salt Chemical class 0.000 abstract 2
- 125000006633 tert-butoxycarbonylamino group Chemical group 0.000 abstract 2
- 229930195708 Penicillin V Natural products 0.000 abstract 1
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical class CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 229940056367 penicillin v Drugs 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1099868A CH542876A (de) | 1968-07-23 | 1968-07-23 | Verfahren zur Herstellung von thiazacyclischen Hydroxyverbindungen |
| CH1850868 | 1968-12-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1281549A true GB1281549A (en) | 1972-07-12 |
Family
ID=25707639
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB57065/71A Expired GB1281549A (en) | 1968-07-23 | 1969-07-16 | Thiazacyclic amino compounds and process for their manufacture |
| GB35885/69A Expired GB1281548A (en) | 1968-07-23 | 1969-07-16 | Thiazacyclic hydroxy compounds and process for their manufacture |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB35885/69A Expired GB1281548A (en) | 1968-07-23 | 1969-07-16 | Thiazacyclic hydroxy compounds and process for their manufacture |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3705160A (enExample) |
| AT (1) | AT294311B (enExample) |
| BE (1) | BE736357A (enExample) |
| ES (1) | ES369741A1 (enExample) |
| FR (1) | FR2013556A1 (enExample) |
| GB (2) | GB1281549A (enExample) |
| IE (1) | IE33234B1 (enExample) |
| NL (1) | NL6911231A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2059491B1 (enExample) * | 1969-07-08 | 1974-05-24 | Ciba Geigy Ag | |
| US4172832A (en) * | 1970-10-27 | 1979-10-30 | Ciba-Geigy Corporation | Mercaptoalcohols and process for their manufacture |
-
1969
- 1969-07-15 US US842028A patent/US3705160A/en not_active Expired - Lifetime
- 1969-07-16 GB GB57065/71A patent/GB1281549A/en not_active Expired
- 1969-07-16 GB GB35885/69A patent/GB1281548A/en not_active Expired
- 1969-07-16 IE IE983/69A patent/IE33234B1/xx unknown
- 1969-07-22 NL NL6911231A patent/NL6911231A/xx unknown
- 1969-07-22 ES ES369741A patent/ES369741A1/es not_active Expired
- 1969-07-22 AT AT703969A patent/AT294311B/de not_active IP Right Cessation
- 1969-07-22 BE BE736357D patent/BE736357A/xx unknown
- 1969-07-23 FR FR6925167A patent/FR2013556A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| NL6911231A (enExample) | 1970-01-27 |
| IE33234L (en) | 1970-01-23 |
| IE33234B1 (en) | 1974-05-01 |
| AT294311B (de) | 1971-11-25 |
| FR2013556A1 (enExample) | 1970-04-03 |
| BE736357A (enExample) | 1970-01-22 |
| ES369741A1 (es) | 1971-04-01 |
| GB1281548A (en) | 1972-07-12 |
| US3705160A (en) | 1972-12-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |