GB1278757A - New process for the preparation of 5-nitrodimidazole derivatives - Google Patents
New process for the preparation of 5-nitrodimidazole derivativesInfo
- Publication number
- GB1278757A GB1278757A GB21739/71A GB2173971A GB1278757A GB 1278757 A GB1278757 A GB 1278757A GB 21739/71 A GB21739/71 A GB 21739/71A GB 2173971 A GB2173971 A GB 2173971A GB 1278757 A GB1278757 A GB 1278757A
- Authority
- GB
- United Kingdom
- Prior art keywords
- derivatives
- formula
- nitration
- alkyl
- nitrodimidazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 4
- 238000006396 nitration reaction Methods 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229940058965 antiprotozoal agent against amoebiasis and other protozoal diseases nitroimidazole derivative Drugs 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 150000004957 nitroimidazoles Chemical class 0.000 abstract 2
- -1 5-nitroimidazole compound Chemical class 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7005444A FR2079880A5 (enExample) | 1970-02-16 | 1970-02-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1278757A true GB1278757A (en) | 1972-06-21 |
Family
ID=9050726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB21739/71A Expired GB1278757A (en) | 1970-02-16 | 1971-04-19 | New process for the preparation of 5-nitrodimidazole derivatives |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS4980066A (enExample) |
| BE (1) | BE762991A (enExample) |
| CA (1) | CA920604A (enExample) |
| CH (1) | CH513178A (enExample) |
| DE (1) | DE2107405A1 (enExample) |
| FR (1) | FR2079880A5 (enExample) |
| GB (1) | GB1278757A (enExample) |
| IL (1) | IL36193A0 (enExample) |
| NL (1) | NL7101642A (enExample) |
| OA (1) | OA03569A (enExample) |
| YU (1) | YU36671A (enExample) |
| ZA (1) | ZA71917B (enExample) |
-
1970
- 1970-02-16 FR FR7005444A patent/FR2079880A5/fr not_active Expired
-
1971
- 1971-02-06 OA OA54166A patent/OA03569A/xx unknown
- 1971-02-08 NL NL7101642A patent/NL7101642A/xx unknown
- 1971-02-15 CH CH215371A patent/CH513178A/fr not_active IP Right Cessation
- 1971-02-15 JP JP46006732A patent/JPS4980066A/ja active Pending
- 1971-02-15 CA CA105410A patent/CA920604A/en not_active Expired
- 1971-02-15 BE BE762991A patent/BE762991A/xx unknown
- 1971-02-15 ZA ZA710917A patent/ZA71917B/xx unknown
- 1971-02-15 IL IL36193A patent/IL36193A0/xx unknown
- 1971-02-16 YU YU00366/71A patent/YU36671A/xx unknown
- 1971-02-16 DE DE19712107405 patent/DE2107405A1/de active Pending
- 1971-04-19 GB GB21739/71A patent/GB1278757A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| YU36671A (en) | 1976-12-31 |
| NL7101642A (enExample) | 1971-08-18 |
| CH513178A (fr) | 1971-09-30 |
| OA03569A (fr) | 1971-03-30 |
| ZA71917B (en) | 1972-06-28 |
| JPS4980066A (enExample) | 1974-08-02 |
| FR2079880A5 (enExample) | 1971-11-12 |
| CA920604A (en) | 1973-02-06 |
| DE2107405A1 (de) | 1971-09-02 |
| IL36193A0 (en) | 1971-04-28 |
| BE762991A (fr) | 1971-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLE | Entries relating assignments, transmissions, licences in the register of patents | ||
| PCNP | Patent ceased through non-payment of renewal fee |