GB1274453A - Bronchodilatory compositions and nebulizers containing them - Google Patents
Bronchodilatory compositions and nebulizers containing themInfo
- Publication number
- GB1274453A GB1274453A GB3598569A GB3598569A GB1274453A GB 1274453 A GB1274453 A GB 1274453A GB 3598569 A GB3598569 A GB 3598569A GB 3598569 A GB3598569 A GB 3598569A GB 1274453 A GB1274453 A GB 1274453A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxy
- trans
- bronchodilatory
- double bond
- oxocyclopentyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000003182 bronchodilatating effect Effects 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- -1 prostaglandin compounds Chemical class 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 239000004338 Dichlorodifluoromethane Substances 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 abstract 2
- 235000019404 dichlorodifluoromethane Nutrition 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- DDMOUSALMHHKOS-UHFFFAOYSA-N 1,2-dichloro-1,1,2,2-tetrafluoroethane Chemical compound FC(F)(Cl)C(F)(F)Cl DDMOUSALMHHKOS-UHFFFAOYSA-N 0.000 abstract 1
- DPOINJQWXDTOSF-UHFFFAOYSA-N 13,14-dihydro-15(R)-Prostaglandin E1 Chemical compound CCCCCC(O)CCC1C(O)CC(=O)C1CCCCCCC(O)=O DPOINJQWXDTOSF-UHFFFAOYSA-N 0.000 abstract 1
- SAKGBZWJAIABSY-UHFFFAOYSA-N 7-[3,5-dihydroxy-2-(3-hydroxyocta-1,5-dienyl)cyclopentyl]hept-5-enoic acid Chemical compound CCC=CCC(O)C=CC1C(O)CC(O)C1CC=CCCCC(O)=O SAKGBZWJAIABSY-UHFFFAOYSA-N 0.000 abstract 1
- GMVPRGQOIOIIMI-UHFFFAOYSA-N 7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-oxocyclopentyl]heptanoic acid Chemical compound CCCCCC(O)C=CC1C(O)CC(=O)C1CCCCCCC(O)=O GMVPRGQOIOIIMI-UHFFFAOYSA-N 0.000 abstract 1
- DZUXGQBLFALXCR-UHFFFAOYSA-N Prostaglandin F1a Chemical compound CCCCCC(O)C=CC1C(O)CC(O)C1CCCCCCC(O)=O DZUXGQBLFALXCR-UHFFFAOYSA-N 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 229940087091 dichlorotetrafluoroethane Drugs 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
- CBOMORHDRONZRN-QLOYDKTKSA-N prostaglandin E3 Chemical compound CC\C=C/C[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O CBOMORHDRONZRN-QLOYDKTKSA-N 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74960668A | 1968-08-02 | 1968-08-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1274453A true GB1274453A (en) | 1972-05-17 |
Family
ID=25014441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3598569A Expired GB1274453A (en) | 1968-08-02 | 1969-07-17 | Bronchodilatory compositions and nebulizers containing them |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE736977A (enrdf_load_stackoverflow) |
| DE (1) | DE1939331A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2014972A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1274453A (enrdf_load_stackoverflow) |
| PH (1) | PH9324A (enrdf_load_stackoverflow) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3069322A (en) * | 1958-05-28 | 1962-12-18 | Bergstrom Sune | Pge and pgf |
| US3290226A (en) * | 1964-02-19 | 1966-12-06 | Upjohn Co | Microbiological conversion of unsaturated fatty acids |
-
1969
- 1969-07-17 GB GB3598569A patent/GB1274453A/en not_active Expired
- 1969-07-24 PH PH10559*UA patent/PH9324A/en unknown
- 1969-08-01 DE DE19691939331 patent/DE1939331A1/de active Pending
- 1969-08-01 FR FR6926581A patent/FR2014972A1/fr not_active Withdrawn
- 1969-08-01 BE BE736977D patent/BE736977A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE736977A (enrdf_load_stackoverflow) | 1970-02-02 |
| DE1939331A1 (de) | 1970-02-05 |
| PH9324A (en) | 1975-09-23 |
| FR2014972A1 (enrdf_load_stackoverflow) | 1970-04-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |