GB1273897A - IMIDAZO AND PYRIMIDO[2,1-b]QUINAZOLINE COMPOUNDS - Google Patents

IMIDAZO AND PYRIMIDO[2,1-b]QUINAZOLINE COMPOUNDS

Info

Publication number
GB1273897A
GB1273897A GB59648/70A GB5964870A GB1273897A GB 1273897 A GB1273897 A GB 1273897A GB 59648/70 A GB59648/70 A GB 59648/70A GB 5964870 A GB5964870 A GB 5964870A GB 1273897 A GB1273897 A GB 1273897A
Authority
GB
United Kingdom
Prior art keywords
prepared
reacting
alkanoyl
alkyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB59648/70A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of GB1273897A publication Critical patent/GB1273897A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB59648/70A 1969-12-18 1970-12-16 IMIDAZO AND PYRIMIDO[2,1-b]QUINAZOLINE COMPOUNDS Expired GB1273897A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88637069A 1969-12-18 1969-12-18

Publications (1)

Publication Number Publication Date
GB1273897A true GB1273897A (en) 1972-05-10

Family

ID=25388927

Family Applications (1)

Application Number Title Priority Date Filing Date
GB59648/70A Expired GB1273897A (en) 1969-12-18 1970-12-16 IMIDAZO AND PYRIMIDO[2,1-b]QUINAZOLINE COMPOUNDS

Country Status (14)

Country Link
US (1) US3621025A (https=)
JP (1) JPS4932879B1 (https=)
BE (1) BE760013A (https=)
CH (1) CH565795A5 (https=)
DE (1) DE2062024A1 (https=)
ES (1) ES386402A1 (https=)
FR (1) FR2081375B1 (https=)
GB (1) GB1273897A (https=)
HU (1) HU163940B (https=)
LU (1) LU62240A1 (https=)
NL (1) NL7018335A (https=)
NO (1) NO129745B (https=)
SE (1) SE363638B (https=)
ZA (1) ZA707817B (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887559A (en) * 1971-07-15 1975-06-03 Sandoz Ag Pharmacologically active tricyclic quinazolinones
US3875161A (en) * 1971-07-15 1975-04-01 Sandoz Ag Imidazo(2,1-b)quinazolin-5(1OH)-ones
US3905976A (en) * 1971-11-24 1975-09-16 Sandoz Ag Substituted tricyclic quinazolinones
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
BE794964A (fr) * 1972-02-04 1973-08-02 Bristol Myers Co Nouveaux agents hypotenseurs et procede pour les preparer
USRE31617E (en) * 1972-02-04 1984-06-26 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
FI56012C (fi) * 1972-09-22 1979-11-12 Bristol Myers Co Foerfarande foer framstaellning av blodtrycksnedsaettande 1h-2,3,4,5-tetrahydroimidazo(2,1-b)kinazolin-2-oner och 1,2,3,4,5,6-hexahydropyrimido(2,1-b)kinazolin-2-oner
US3875160A (en) * 1973-01-22 1975-04-01 Goetz E Hardtmann Quaternary-tricyclic quinazolinones
US3984556A (en) * 1973-01-19 1976-10-05 Sandoz, Inc. Alkyl-substituted-tricyclic quinazolinones for lowering blood pressure
US3894022A (en) * 1973-06-25 1975-07-08 Sandoz Ag Tetracyclic quinazolinones and quinazolinium salts
JPS5752352B2 (https=) * 1974-02-28 1982-11-06
US3983120A (en) * 1974-11-06 1976-09-28 Bristol-Myers Company Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones
US3983119A (en) * 1974-11-06 1976-09-28 Bristol-Myers Company Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones
JPS5448797A (en) * 1977-09-06 1979-04-17 Sumitomo Chem Co Ltd Tricyclic condensed pyrimidine derivative and its preparation
EP0029559A3 (en) * 1979-11-24 1981-09-30 Sandoz Ag 5,10-dihydroimidazo(2,1-b)quinazolines, their production and pharmaceutical compositions containing them
US4452787A (en) * 1981-09-16 1984-06-05 Sandoz, Inc. 1-Substituted tricyclic quinazolinones having biological activity as tranquilizers
PH17745A (en) * 1981-09-16 1984-11-27 Sandoz Ag Trifluoromethyl substituted tricyclic quinazolinones
US4760065A (en) * 1986-02-13 1988-07-26 Hardtmann Goetz E Trifluoromethyl substituted tetracyclic quinazolin-ones having tranquilizing activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3257401A (en) * 1964-06-18 1966-06-21 Searle & Co 5-hydroxy-2-methylcycloalkyl[d] imidazo[1, 2-a]pyrimidines

Also Published As

Publication number Publication date
FR2081375A1 (https=) 1971-12-03
NO129745B (https=) 1974-05-20
CH565795A5 (https=) 1975-08-29
DE2062024A1 (de) 1972-05-25
NL7018335A (https=) 1971-06-22
HU163940B (https=) 1973-11-28
ES386402A1 (es) 1973-03-16
BE760013A (fr) 1971-06-08
SE363638B (https=) 1974-01-28
FR2081375B1 (https=) 1974-08-23
JPS4932879B1 (https=) 1974-09-03
ZA707817B (en) 1971-08-25
LU62240A1 (https=) 1971-07-27
US3621025A (en) 1971-11-16

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee