GB1264261A - - Google Patents
Info
- Publication number
- GB1264261A GB1264261A GB1264261DA GB1264261A GB 1264261 A GB1264261 A GB 1264261A GB 1264261D A GB1264261D A GB 1264261DA GB 1264261 A GB1264261 A GB 1264261A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methoxy
- methyl
- prepared
- amino
- methylsulphonylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 amino, methylmercapto, methoxy, methylsulphonyl Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- CFMZSMGAMPBRBE-UHFFFAOYSA-N 2-hydroxyisoindole-1,3-dione Chemical compound C1=CC=C2C(=O)N(O)C(=O)C2=C1 CFMZSMGAMPBRBE-UHFFFAOYSA-N 0.000 abstract 1
- IOZADUIJKWISQS-UHFFFAOYSA-N 2-phenylmethoxyisoindole-1,3-dione Chemical compound O=C1C2=CC=CC=C2C(=O)N1OCC1=CC=CC=C1 IOZADUIJKWISQS-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- QARBMVPHQWIHKH-UHFFFAOYSA-N methanesulfonyl chloride Chemical compound CS(Cl)(=O)=O QARBMVPHQWIHKH-UHFFFAOYSA-N 0.000 abstract 1
- GTUWALDPIDUBBV-UHFFFAOYSA-N methyl 3-(methanesulfonamido)-4-methoxybenzoate Chemical compound COC(=O)C1=CC=C(OC)C(NS(C)(=O)=O)=C1 GTUWALDPIDUBBV-UHFFFAOYSA-N 0.000 abstract 1
- QVDWKLDUBSJEOG-UHFFFAOYSA-N methyl 3-amino-4-methoxybenzoate Chemical compound COC(=O)C1=CC=C(OC)C(N)=C1 QVDWKLDUBSJEOG-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- IGLNBLSWLLNOLF-UHFFFAOYSA-N n-phenylmethoxypropan-2-imine Chemical compound CC(C)=NOCC1=CC=CC=C1 IGLNBLSWLLNOLF-UHFFFAOYSA-N 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- XYEOALKITRFCJJ-UHFFFAOYSA-N o-benzylhydroxylamine Chemical class NOCC1=CC=CC=C1 XYEOALKITRFCJJ-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000005544 phthalimido group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUGO001085 | 1969-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1264261A true GB1264261A (enrdf_load_stackoverflow) | 1972-02-16 |
Family
ID=10996669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1264261D Expired GB1264261A (enrdf_load_stackoverflow) | 1969-02-10 | 1970-02-05 |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE2005907A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2034533B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1264261A (enrdf_load_stackoverflow) |
| NL (1) | NL7001789A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10047066B2 (en) | 2007-11-30 | 2018-08-14 | Newlink Genetics Corporation | IDO inhibitors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE640150A (enrdf_load_stackoverflow) * | 1963-02-11 |
-
1970
- 1970-02-05 GB GB1264261D patent/GB1264261A/en not_active Expired
- 1970-02-09 NL NL7001789A patent/NL7001789A/xx unknown
- 1970-02-10 DE DE19702005907 patent/DE2005907A1/de active Pending
- 1970-02-10 FR FR7004632A patent/FR2034533B1/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10047066B2 (en) | 2007-11-30 | 2018-08-14 | Newlink Genetics Corporation | IDO inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7001789A (enrdf_load_stackoverflow) | 1970-08-12 |
| FR2034533A1 (enrdf_load_stackoverflow) | 1970-12-11 |
| FR2034533B1 (enrdf_load_stackoverflow) | 1973-04-06 |
| DE2005907A1 (de) | 1970-09-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |