GB1263343A - Delta<2>-CEPHEM-4-CARBOXYLIC ACID ESTERS - Google Patents
Delta<2>-CEPHEM-4-CARBOXYLIC ACID ESTERSInfo
- Publication number
- GB1263343A GB1263343A GB39210/69A GB3921069A GB1263343A GB 1263343 A GB1263343 A GB 1263343A GB 39210/69 A GB39210/69 A GB 39210/69A GB 3921069 A GB3921069 A GB 3921069A GB 1263343 A GB1263343 A GB 1263343A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cephem
- carboxylic acid
- acid esters
- formula
- delta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/60—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 3 and 4
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B17/00—Machines or apparatus for drying materials in loose, plastic, or fluidised form, e.g. granules, staple fibres, with progressive movement
- F26B17/12—Machines or apparatus for drying materials in loose, plastic, or fluidised form, e.g. granules, staple fibres, with progressive movement with movement performed solely by gravity, i.e. the material moving through a substantially vertical drying enclosure, e.g. shaft
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Cephalosporin Compounds (AREA)
Abstract
1,263,343. Cephem-4-carboxylic acid esters. ELI LILLY & CO. 5 Aug., 1969 [12 Sept., 1968], No. 39210/69. Heading C2A. #<SP>2</SP>-Cephem-4-carboxylic acid esters having the formula are prepared by (a) converting a #<SP>3</SP>-cephem-4- carboxylic acid having the formula to the corresponding acid chloride; and (b) treating the acid chloride with 1-2 moles of a tertiary amine base having a pKa within the range of 7-11 and at least 1 mole of an esterforming aliphatic alcohol (as defined) having the formula R<SP>1</SP>OH at a temperature within the range of -100 to +50 C.; wherein X is hydrogen or acetoxy, R is an amino protecting group, and R<SP>1</SP> is the residue of the ester-forming alcohol. The compounds having the following formulae are stated to be novel and are claimed per se:
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75949068A | 1968-09-12 | 1968-09-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1263343A true GB1263343A (en) | 1972-02-09 |
Family
ID=25055841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB39210/69A Expired GB1263343A (en) | 1968-09-12 | 1969-08-05 | Delta<2>-CEPHEM-4-CARBOXYLIC ACID ESTERS |
Country Status (10)
Country | Link |
---|---|
JP (1) | JPS5013276B1 (en) |
BE (1) | BE737123A (en) |
CH (1) | CH519517A (en) |
DE (1) | DE1940081C3 (en) |
DK (1) | DK139725B (en) |
FR (1) | FR2017860A1 (en) |
GB (1) | GB1263343A (en) |
IE (1) | IE33537B1 (en) |
IL (1) | IL32545A (en) |
NL (1) | NL165750C (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3849408A (en) * | 1971-05-03 | 1974-11-19 | Squibb & Sons Inc | 4-substituted-delta2-cephalosporin derivatives |
JPS5254972U (en) * | 1975-10-18 | 1977-04-20 |
-
1969
- 1969-07-02 IE IE906/69A patent/IE33537B1/en unknown
- 1969-07-03 IL IL32545A patent/IL32545A/en unknown
- 1969-07-31 NL NL6911731.A patent/NL165750C/en not_active IP Right Cessation
- 1969-08-04 JP JP6961098A patent/JPS5013276B1/ja active Pending
- 1969-08-05 DK DK421069AA patent/DK139725B/en unknown
- 1969-08-05 GB GB39210/69A patent/GB1263343A/en not_active Expired
- 1969-08-06 BE BE737123D patent/BE737123A/xx unknown
- 1969-08-06 DE DE1940081A patent/DE1940081C3/en not_active Expired
- 1969-08-06 CH CH1194569A patent/CH519517A/en not_active IP Right Cessation
- 1969-08-06 FR FR6927054A patent/FR2017860A1/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
IE33537L (en) | 1970-03-19 |
JPS5013276B1 (en) | 1975-05-19 |
DE1940081B2 (en) | 1973-09-27 |
IL32545A (en) | 1974-05-16 |
IL32545A0 (en) | 1969-11-12 |
NL165750B (en) | 1980-12-15 |
NL165750C (en) | 1981-05-15 |
DK139725B (en) | 1979-04-02 |
DK139725C (en) | 1979-09-17 |
CH519517A (en) | 1972-02-29 |
DE1940081A1 (en) | 1970-05-06 |
IE33537B1 (en) | 1974-08-07 |
BE737123A (en) | 1970-02-06 |
FR2017860A1 (en) | 1970-05-22 |
NL6911731A (en) | 1970-03-16 |
DE1940081C3 (en) | 1974-05-02 |
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