GB1260971A - SUBSTITUTED-1,2,3,4-TETRAHYDROBENZOTHIENO-(2,3-c)PYRIDINES - Google Patents
SUBSTITUTED-1,2,3,4-TETRAHYDROBENZOTHIENO-(2,3-c)PYRIDINESInfo
- Publication number
- GB1260971A GB1260971A GB433370A GB433370A GB1260971A GB 1260971 A GB1260971 A GB 1260971A GB 433370 A GB433370 A GB 433370A GB 433370 A GB433370 A GB 433370A GB 1260971 A GB1260971 A GB 1260971A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetrahydrobenzothieno
- pyridines
- treating
- substituted
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
1,260,971. Tetrahydrobenzothieno[2,3-c]pyridines. COLGATE-PALMOLIVE CO. 29 Jan., 1970, No. 4333/70. Heading C2C. The invention comprises compounds of formula and their pharmaceutically acceptable acid addition salts, wherein A and A 1 are each H, OH, NO 2 , C 1-14 alkyl or alkoxy, F, Cl, Br, I or CF 3 (but A and A 1 may not both be H), and processes for preparing them by (a) treating the corresponding 2-(benzothienyl)ethylamine with paraformaldehyde at elevated temperature, or (b) treating the corresponding lactam with a chemical reducing agent. Details are also given for the preparation of starting materials and in which X is 5-chlorobenzothienyl. Therapeutic compositions comprise compounds of the above formula, which have antipsychotic properties. Administration may be oral or parenteral.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB433370A GB1260971A (en) | 1970-01-29 | 1970-01-29 | SUBSTITUTED-1,2,3,4-TETRAHYDROBENZOTHIENO-(2,3-c)PYRIDINES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB433370A GB1260971A (en) | 1970-01-29 | 1970-01-29 | SUBSTITUTED-1,2,3,4-TETRAHYDROBENZOTHIENO-(2,3-c)PYRIDINES |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1260971A true GB1260971A (en) | 1972-01-19 |
Family
ID=9775199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB433370A Expired GB1260971A (en) | 1970-01-29 | 1970-01-29 | SUBSTITUTED-1,2,3,4-TETRAHYDROBENZOTHIENO-(2,3-c)PYRIDINES |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1260971A (en) |
-
1970
- 1970-01-29 GB GB433370A patent/GB1260971A/en not_active Expired
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