GB1257960A - - Google Patents
Info
- Publication number
- GB1257960A GB1257960A GB1257960DA GB1257960A GB 1257960 A GB1257960 A GB 1257960A GB 1257960D A GB1257960D A GB 1257960DA GB 1257960 A GB1257960 A GB 1257960A
- Authority
- GB
- United Kingdom
- Prior art keywords
- substituted
- compounds
- tetrahydropyridine
- hydroxymethyl
- hexyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- MNAFWXHINGUUKY-UHFFFAOYSA-N (1-hexyl-3,6-dihydro-2H-pyridin-5-yl)methanol Chemical compound C(CCCCC)N1CC(=CCC1)CO MNAFWXHINGUUKY-UHFFFAOYSA-N 0.000 abstract 1
- KOCBHAYDENABKT-UHFFFAOYSA-M (1-hexylpyridin-1-ium-3-yl)methanol bromide Chemical compound [Br-].C(CCCCC)[N+]1=CC(=CC=C1)CO KOCBHAYDENABKT-UHFFFAOYSA-M 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000006704 (C5-C6) cycloalkyl group Chemical group 0.000 abstract 1
- -1 N-substituted 3-hydroxymethyl - 1,2,5,6 - tetrahydropyridine Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT609868A AT287711B (de) | 1968-06-25 | 1968-06-25 | Verfahren zur Herstellung von neuen 1-Alkyl-1,2,5,6-tetrahydro-3-pyridylmethyl-carbonsäureestern sowie deren Säureadditionssalzen und quaternären Ammoniumverbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1257960A true GB1257960A (enrdf_load_stackoverflow) | 1971-12-22 |
Family
ID=3582843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1257960D Expired GB1257960A (enrdf_load_stackoverflow) | 1968-06-25 | 1969-06-25 |
Country Status (11)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4467095A (en) * | 1969-02-10 | 1984-08-21 | Fmc Corporation | Anticholinergic compounds |
| US3879556A (en) * | 1970-09-02 | 1975-04-22 | Boehringer Sohn Ingelheim | Pharmaceutical compositions containing a 1,2,3,6-tetrahydro-4-pyridylmethyl carboxylate and method of use |
| DE2043455A1 (de) * | 1970-09-02 | 1972-03-09 | CH. Boehringer Sohn, 6507 Ingelheim | Neue l,2,3,6-tetrahydro-4-pyridylmethyl-carbonsäureester, sowie deren Säureadditionssalze und quarternären Ammoniumverbindungen |
| FR2501682A1 (fr) * | 1981-03-11 | 1982-09-17 | Sanofi Sa | Trifluoromethylphenylpyridines a activite anorexigene, un procede de preparation et compositions pharmaceutiques en contenant |
| DE3801659A1 (de) * | 1988-01-21 | 1989-07-27 | Boehringer Ingelheim Kg | Tetrahydropyridin - derivate |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2607777A (en) * | 1947-04-10 | 1952-08-19 | Searle & Co | N-alkyl piperidyl alkyl esters of diphenyl acetic acid and 9-fluorenyl carboxylic acid |
| GB886437A (en) * | 1959-07-15 | 1962-01-10 | Beecham Res Lab | Improvements in or relating to basic esters of etherified benzilic acids |
-
1968
- 1968-06-25 AT AT609868A patent/AT287711B/de not_active IP Right Cessation
-
1969
- 1969-06-12 DE DE19691929921 patent/DE1929921A1/de active Pending
- 1969-06-19 NL NL6909425A patent/NL6909425A/xx unknown
- 1969-06-23 ES ES368698A patent/ES368698A1/es not_active Expired
- 1969-06-23 CH CH958769A patent/CH513164A/de not_active IP Right Cessation
- 1969-06-24 BR BR210094/69A patent/BR6910094D0/pt unknown
- 1969-06-24 IL IL32469A patent/IL32469A0/xx unknown
- 1969-06-25 FR FR6921376A patent/FR2014218A1/fr not_active Withdrawn
- 1969-06-25 US US836658A patent/US3627775A/en not_active Expired - Lifetime
- 1969-06-25 BE BE735141D patent/BE735141A/xx unknown
- 1969-06-25 GB GB1257960D patent/GB1257960A/en not_active Expired
- 1969-12-10 ES ES374408A patent/ES374408A1/es not_active Expired
- 1969-12-10 ES ES374407A patent/ES374407A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL32469A0 (en) | 1969-08-27 |
| FR2014218A1 (enrdf_load_stackoverflow) | 1970-04-17 |
| DE1929921A1 (de) | 1970-01-02 |
| AT287711B (de) | 1971-02-10 |
| NL6909425A (enrdf_load_stackoverflow) | 1969-12-30 |
| BR6910094D0 (pt) | 1973-04-05 |
| US3627775A (en) | 1971-12-14 |
| ES368698A1 (es) | 1971-07-01 |
| CH513164A (de) | 1971-09-30 |
| ES374408A1 (es) | 1972-01-01 |
| ES374407A1 (es) | 1972-01-01 |
| BE735141A (enrdf_load_stackoverflow) | 1969-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |