GB1246495A - Penicillins and their production - Google Patents
Penicillins and their productionInfo
- Publication number
- GB1246495A GB1246495A GB59874/68A GB5987468A GB1246495A GB 1246495 A GB1246495 A GB 1246495A GB 59874/68 A GB59874/68 A GB 59874/68A GB 5987468 A GB5987468 A GB 5987468A GB 1246495 A GB1246495 A GB 1246495A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- formula
- acid
- penicillin
- penicillins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930182555 Penicillin Natural products 0.000 title abstract 6
- 150000002960 penicillins Chemical class 0.000 title abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- 125000005842 heteroatom Chemical group 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- AVKUERGKIZMTKX-YXLKDIQASA-N (2s,5r)-6-[(2-amino-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Chemical compound C1([C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)NC(=O)C(N)C1=CC=CC=C1 AVKUERGKIZMTKX-YXLKDIQASA-N 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- IJOOHPMOJXWVHK-UHFFFAOYSA-N chlorotrimethylsilane Chemical compound C[Si](C)(C)Cl IJOOHPMOJXWVHK-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 229940049954 penicillin Drugs 0.000 abstract 2
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 1
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 1
- KNIUHBNRWZGIQQ-UHFFFAOYSA-N 7-diethoxyphosphinothioyloxy-4-methylchromen-2-one Chemical compound CC1=CC(=O)OC2=CC(OP(=S)(OCC)OCC)=CC=C21 KNIUHBNRWZGIQQ-UHFFFAOYSA-N 0.000 abstract 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- -1 acyl isothiocyanate Chemical class 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- OJKZEZMAPKWHTG-UHFFFAOYSA-N bis(2h-triazol-4-yl)methanone Chemical compound C=1NN=NC=1C(=O)C1=CNN=N1 OJKZEZMAPKWHTG-UHFFFAOYSA-N 0.000 abstract 1
- 150000001718 carbodiimides Chemical class 0.000 abstract 1
- PFKFTWBEEFSNDU-UHFFFAOYSA-N carbonyldiimidazole Chemical compound C1=CN=CN1C(=O)N1C=CN=C1 PFKFTWBEEFSNDU-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 208000004396 mastitis Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical class OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 abstract 1
- 239000005051 trimethylchlorosilane Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19671670963 DE1670963A1 (de) | 1967-12-10 | 1967-12-18 | Neue Penicilline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1246495A true GB1246495A (en) | 1971-09-15 |
Family
ID=5686356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB59874/68A Expired GB1246495A (en) | 1967-12-18 | 1968-12-17 | Penicillins and their production |
Country Status (11)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105859746A (zh) * | 2016-03-22 | 2016-08-17 | 江西富祥药业股份有限公司 | 一种合成阿扑西林的方法 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2218340B1 (enrdf_load_stackoverflow) * | 1973-02-16 | 1978-09-29 | Rhone Poulenc Ind |
-
1968
- 1968-12-02 CH CH1803168A patent/CH535789A/de not_active IP Right Cessation
- 1968-12-11 AT AT1206568A patent/AT283593B/de not_active IP Right Cessation
- 1968-12-16 IL IL31275A patent/IL31275A/xx unknown
- 1968-12-16 NL NL6818057A patent/NL6818057A/xx unknown
- 1968-12-17 SE SE6817283A patent/SE373587B/xx unknown
- 1968-12-17 DK DK617468A patent/DK133433C/da active
- 1968-12-17 GB GB59874/68A patent/GB1246495A/en not_active Expired
- 1968-12-18 FR FR1601138D patent/FR1601138A/fr not_active Expired
- 1968-12-18 CS CS858968A patent/CS155195B2/cs unknown
- 1968-12-18 BR BR204940/68A patent/BR6804940D0/pt unknown
- 1968-12-18 BE BE725663D patent/BE725663A/xx unknown
-
1969
- 1969-03-18 FR FR183292A patent/FR8263M/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105859746A (zh) * | 2016-03-22 | 2016-08-17 | 江西富祥药业股份有限公司 | 一种合成阿扑西林的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| BR6804940D0 (pt) | 1973-03-20 |
| SE373587B (sv) | 1975-02-10 |
| FR1601138A (enrdf_load_stackoverflow) | 1970-08-10 |
| DK133433B (da) | 1976-05-17 |
| NL6818057A (enrdf_load_stackoverflow) | 1969-06-20 |
| AT283593B (de) | 1970-08-10 |
| IL31275A0 (en) | 1969-02-27 |
| CH535789A (de) | 1973-04-15 |
| IL31275A (en) | 1973-02-28 |
| CS155195B2 (enrdf_load_stackoverflow) | 1974-05-30 |
| DK133433C (da) | 1976-10-11 |
| BE725663A (enrdf_load_stackoverflow) | 1969-06-18 |
| FR8263M (enrdf_load_stackoverflow) | 1970-10-19 |
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