GB1236956A - Epoxypropylphosphonic and thiophosphonic acid derivatives - Google Patents
Epoxypropylphosphonic and thiophosphonic acid derivativesInfo
- Publication number
- GB1236956A GB1236956A GB50634/68A GB5063468A GB1236956A GB 1236956 A GB1236956 A GB 1236956A GB 50634/68 A GB50634/68 A GB 50634/68A GB 5063468 A GB5063468 A GB 5063468A GB 1236956 A GB1236956 A GB 1236956A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- cis
- agents
- salts
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 9
- 229910052760 oxygen Inorganic materials 0.000 abstract 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 4
- 239000007800 oxidant agent Substances 0.000 abstract 4
- 239000001301 oxygen Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- -1 1,2 - Epoxypropyl Chemical group 0.000 abstract 3
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 2
- WGQKYBSKWIADBV-UHFFFAOYSA-N benzylamine Chemical compound NCC1=CC=CC=C1 WGQKYBSKWIADBV-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000004967 organic peroxy acids Chemical class 0.000 abstract 2
- XYPISWUKQGWYGX-UHFFFAOYSA-N 2,2,2-trifluoroethaneperoxoic acid Chemical compound OOC(=O)C(F)(F)F XYPISWUKQGWYGX-UHFFFAOYSA-N 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- BHHGXPLMPWCGHP-UHFFFAOYSA-N Phenethylamine Chemical class NCCC1=CC=CC=C1 BHHGXPLMPWCGHP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000000732 arylene group Chemical group 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- ONANWDUDFJIIGP-UHFFFAOYSA-N carbamoyl carbamoperoxoate Chemical compound NC(=O)OOC(N)=O ONANWDUDFJIIGP-UHFFFAOYSA-N 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 229940042400 direct acting antivirals phosphonic acid derivative Drugs 0.000 abstract 1
- 238000006735 epoxidation reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000003979 granulating agent Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 150000002432 hydroperoxides Chemical class 0.000 abstract 1
- JGJLWPGRMCADHB-UHFFFAOYSA-N hypobromite Inorganic materials Br[O-] JGJLWPGRMCADHB-UHFFFAOYSA-N 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 150000004966 inorganic peroxy acids Chemical class 0.000 abstract 1
- 239000006193 liquid solution Substances 0.000 abstract 1
- 239000006194 liquid suspension Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 125000000864 peroxy group Chemical group O(O*)* 0.000 abstract 1
- 125000004437 phosphorous atom Chemical group 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 150000003573 thiols Chemical class 0.000 abstract 1
- 229910052727 yttrium Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
- C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6587—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having two phosphorus atoms as ring hetero atoms in the same ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72942968A | 1968-05-15 | 1968-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1236956A true GB1236956A (en) | 1971-06-23 |
Family
ID=24930977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB50634/68A Expired GB1236956A (en) | 1968-05-15 | 1968-10-24 | Epoxypropylphosphonic and thiophosphonic acid derivatives |
Country Status (17)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117964661A (zh) * | 2024-04-01 | 2024-05-03 | 深圳创元生物医药科技有限公司 | 一种磷霉素基因毒杂质c的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2770610A (en) * | 1952-10-30 | 1956-11-13 | Monsanto Chemicals | Esters of epoxidized phosphonic acids and halogenated organic materials stabilized therewith |
-
1968
- 1968-10-18 NL NL6814981A patent/NL6814981A/xx unknown
- 1968-10-21 IL IL30915A patent/IL30915A0/xx unknown
- 1968-10-21 IE IE1254/68A patent/IE33077B1/xx unknown
- 1968-10-22 CH CH1578768A patent/CH515937A/de not_active IP Right Cessation
- 1968-10-23 HU HUME997A patent/HU162829B/hu unknown
- 1968-10-24 GB GB50634/68A patent/GB1236956A/en not_active Expired
- 1968-10-24 PL PL1968129715A patent/PL71417B1/pl unknown
- 1968-10-25 ES ES359535A patent/ES359535A1/es not_active Expired
- 1968-10-28 DE DE19681805675 patent/DE1805675A1/de active Pending
- 1968-10-29 LU LU57187D patent/LU57187A1/xx unknown
- 1968-10-29 BE BE723079D patent/BE723079A/xx unknown
- 1968-10-29 BR BR203537/68A patent/BR6803537D0/pt unknown
- 1968-10-29 SE SE14614/68A patent/SE367205B/xx unknown
- 1968-10-30 ZM ZM140/68A patent/ZM14068A1/xx unknown
- 1968-10-30 AT AT1055568A patent/AT299245B/de not_active IP Right Cessation
- 1968-11-11 MT MT584A patent/MTP584B/xx unknown
-
1969
- 1969-05-16 FR FR6915920A patent/FR2008618A1/fr not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117964661A (zh) * | 2024-04-01 | 2024-05-03 | 深圳创元生物医药科技有限公司 | 一种磷霉素基因毒杂质c的制备方法 |
| CN117964661B (zh) * | 2024-04-01 | 2024-06-07 | 深圳创元生物医药科技有限公司 | 一种磷霉素基因毒杂质c的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2008618A1 (US06229276-20010508-P00022.png) | 1970-01-23 |
| IL30915A0 (en) | 1968-12-26 |
| PL71417B1 (US06229276-20010508-P00022.png) | 1974-06-29 |
| IE33077B1 (en) | 1974-03-20 |
| HU162829B (US06229276-20010508-P00022.png) | 1973-04-28 |
| CH515937A (de) | 1971-11-30 |
| NL6814981A (US06229276-20010508-P00022.png) | 1969-11-18 |
| SE367205B (US06229276-20010508-P00022.png) | 1974-05-20 |
| IE33077L (en) | 1969-11-15 |
| BE723079A (US06229276-20010508-P00022.png) | 1969-04-29 |
| ZM14068A1 (en) | 1970-06-18 |
| DE1805675A1 (de) | 1969-12-11 |
| MTP584B (en) | 1970-01-21 |
| LU57187A1 (US06229276-20010508-P00022.png) | 1969-05-16 |
| ES359535A1 (es) | 1970-08-16 |
| BR6803537D0 (pt) | 1973-02-22 |
| AT299245B (de) | 1972-06-12 |
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