GB1228737A - - Google Patents
Info
- Publication number
- GB1228737A GB1228737A GB1228737DA GB1228737A GB 1228737 A GB1228737 A GB 1228737A GB 1228737D A GB1228737D A GB 1228737DA GB 1228737 A GB1228737 A GB 1228737A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aldehyde
- tetracycline
- ketone
- substituted
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001299 aldehydes Chemical class 0.000 abstract 6
- 239000004098 Tetracycline Substances 0.000 abstract 5
- 229960002180 tetracycline Drugs 0.000 abstract 5
- 229930101283 tetracycline Natural products 0.000 abstract 5
- 235000019364 tetracycline Nutrition 0.000 abstract 5
- 150000003522 tetracyclines Chemical class 0.000 abstract 5
- 150000003973 alkyl amines Chemical group 0.000 abstract 3
- 150000002576 ketones Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- -1 ethyleneimino ring Chemical group 0.000 abstract 2
- MNQZXJOMYWMBOU-VKHMYHEASA-N D-glyceraldehyde Chemical compound OC[C@@H](O)C=O MNQZXJOMYWMBOU-VKHMYHEASA-N 0.000 abstract 1
- 238000006683 Mannich reaction Methods 0.000 abstract 1
- IKHGUXGNUITLKF-XPULMUKRSA-N acetaldehyde Chemical compound [14CH]([14CH3])=O IKHGUXGNUITLKF-XPULMUKRSA-N 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 125000005997 bromomethyl group Chemical group 0.000 abstract 1
- 125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000009792 diffusion process Methods 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 150000002373 hemiacetals Chemical class 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR139030 | 1968-02-07 | ||
| FR155657A FR7462M (enrdf_load_stackoverflow) | 1968-06-19 | 1968-06-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1228737A true GB1228737A (enrdf_load_stackoverflow) | 1971-04-15 |
Family
ID=26181783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1228737D Expired GB1228737A (enrdf_load_stackoverflow) | 1968-02-07 | 1969-02-06 |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE726763A (enrdf_load_stackoverflow) |
| CH (1) | CH494737A (enrdf_load_stackoverflow) |
| DE (1) | DE1905280A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1228737A (enrdf_load_stackoverflow) |
| NL (1) | NL6901899A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3178320A1 (de) | 2015-12-11 | 2017-06-14 | Bayer CropScience AG | Flüssige fungizid-haltige formulierungen |
-
1969
- 1969-01-10 BE BE726763D patent/BE726763A/xx unknown
- 1969-01-13 CH CH40069A patent/CH494737A/fr not_active IP Right Cessation
- 1969-02-04 DE DE19691905280 patent/DE1905280A1/de active Pending
- 1969-02-06 NL NL6901899A patent/NL6901899A/xx unknown
- 1969-02-06 GB GB1228737D patent/GB1228737A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE726763A (enrdf_load_stackoverflow) | 1969-06-16 |
| CH494737A (fr) | 1970-08-15 |
| NL6901899A (enrdf_load_stackoverflow) | 1969-08-11 |
| DE1905280A1 (de) | 1970-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |