GB1226727A - - Google Patents
Info
- Publication number
- GB1226727A GB1226727A GB1226727DA GB1226727A GB 1226727 A GB1226727 A GB 1226727A GB 1226727D A GB1226727D A GB 1226727DA GB 1226727 A GB1226727 A GB 1226727A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aminoantipyrine
- benzoic acid
- acid chloride
- methylacetamido
- june
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
- C07D231/46—Oxygen atom in position 3 or 5 and nitrogen atom in position 4
- C07D231/50—Acylated on said nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,226,727. Derivatives of 4-aminoantipyrine. PHARMA CHEMIE. 13 June, 1969 [28 June, 1968], No. 30135/69. Heading C2C. Novel derivatives of 4-aminoantipyrine of the formula in which R is H or C 1-4 alkyl and X is H or CH 3 CO- are prepared by reacting the appropriate 4-aminoantipyrine compound with 4- methylaminobenzoic acid chloride or 4-(N- methylacetamido)-benzoic acid chloride in the presence of a base. 4-(N-Methylacetamido) benzoic acid chloride is obtained by reacting thionyl chloride with 4-(N-onethylacetamido) benzoic acid resulting from the acylation of 4-methylaminobenzoic acid with acetic anhydride. Therapeutic compositions, suitable for oral, rectal, topical or parenteral administration, contain the above novel compounds and pharmaceutically acceptable carriers. The compositions have anti-phlogistic, analgesic, antianaphylactic and anti-pyretic activity.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR157275A FR7492M (en) | 1968-06-28 | 1968-06-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1226727A true GB1226727A (en) | 1971-03-31 |
Family
ID=8651875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1226727D Expired GB1226727A (en) | 1968-06-28 | 1969-06-13 |
Country Status (6)
Country | Link |
---|---|
BE (1) | BE734480A (en) |
CH (1) | CH510670A (en) |
DE (1) | DE1932485A1 (en) |
ES (1) | ES369188A1 (en) |
FR (1) | FR7492M (en) |
GB (1) | GB1226727A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004106306A1 (en) * | 2003-05-30 | 2004-12-09 | Aston University | Novel ureido - and amido-pyrazolone derivatives |
-
1968
- 1968-06-28 FR FR157275A patent/FR7492M/fr not_active Expired
-
1969
- 1969-06-12 BE BE734480D patent/BE734480A/xx unknown
- 1969-06-13 GB GB1226727D patent/GB1226727A/en not_active Expired
- 1969-06-16 CH CH915469A patent/CH510670A/en not_active IP Right Cessation
- 1969-06-26 DE DE19691932485 patent/DE1932485A1/en active Pending
- 1969-06-27 ES ES369188A patent/ES369188A1/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004106306A1 (en) * | 2003-05-30 | 2004-12-09 | Aston University | Novel ureido - and amido-pyrazolone derivatives |
Also Published As
Publication number | Publication date |
---|---|
ES369188A1 (en) | 1971-05-16 |
BE734480A (en) | 1969-11-17 |
FR7492M (en) | 1969-12-08 |
DE1932485A1 (en) | 1970-01-08 |
CH510670A (en) | 1971-07-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB1322988A (en) | Thiaheterocyclyl-acetic acid derivatives | |
GB1459065A (en) | Therapeutic thiophene derivatives | |
GB1358624A (en) | Phenylacetic acid derivatives process for their preparation and applications thereof | |
ES359454A1 (en) | 2-anilino-nicotinic acid esters | |
ES374549A1 (en) | Thiazolyl benzoic acid compounds | |
GB1234490A (en) | ||
GB1308028A (en) | Thiazolylbenzoic acid derivatives and a process for their manufactur | |
GB1471910A (en) | Lysine salt | |
GB1226727A (en) | ||
GB1437868A (en) | Arylpiperazinoalkyl esters | |
GB1386664A (en) | Aminothiophene-carboxylic acid esters and process for their preparation | |
GB1299201A (en) | Medicaments derived from thiazolidine carboxylic acid | |
GB1237054A (en) | Derivatives of the 2-(lower alkyl)-3-(lower alkyl)-4-phenyl-3- or 4-cyclohexenecarboxylic acids | |
GB1173687A (en) | Pyridyl-Tetrahydroisoquinolines | |
GB1462676A (en) | Substituted esters of n-4-quinolyl-anthranilic acids | |
GB1379009A (en) | Acetylsalicylic acid esters | |
GB1263116A (en) | Chloramphenicol and thiamphenicol derivatives | |
GB1276359A (en) | Anthranilic acid derivatives | |
GB1504683A (en) | Pharmaceutical compositions containing substituted pyrimido-quinoline derivatives | |
GB1242096A (en) | Benzobenzofuranooxepine compounds and process for preparing the same | |
GB1513280A (en) | Therapeutic pyrazole derivatives | |
GB1381128A (en) | Anthranilic acid derivative | |
ES434751A1 (en) | Pharmaceutically useful indanylpropionic acid derivatives | |
GB1335403A (en) | Pharmaceutical compositions containing benzofuran derivatives | |
GB1341329A (en) | Indole derivatives process for producing them and compositions containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |