GB1226727A - - Google Patents

Info

Publication number
GB1226727A
GB1226727A GB1226727DA GB1226727A GB 1226727 A GB1226727 A GB 1226727A GB 1226727D A GB1226727D A GB 1226727DA GB 1226727 A GB1226727 A GB 1226727A
Authority
GB
United Kingdom
Prior art keywords
aminoantipyrine
benzoic acid
acid chloride
methylacetamido
june
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1226727A publication Critical patent/GB1226727A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
    • C07D231/46—Oxygen atom in position 3 or 5 and nitrogen atom in position 4
    • C07D231/50—Acylated on said nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,226,727. Derivatives of 4-aminoantipyrine. PHARMA CHEMIE. 13 June, 1969 [28 June, 1968], No. 30135/69. Heading C2C. Novel derivatives of 4-aminoantipyrine of the formula in which R is H or C 1-4 alkyl and X is H or CH 3 CO- are prepared by reacting the appropriate 4-aminoantipyrine compound with 4- methylaminobenzoic acid chloride or 4-(N- methylacetamido)-benzoic acid chloride in the presence of a base. 4-(N-Methylacetamido) benzoic acid chloride is obtained by reacting thionyl chloride with 4-(N-onethylacetamido) benzoic acid resulting from the acylation of 4-methylaminobenzoic acid with acetic anhydride. Therapeutic compositions, suitable for oral, rectal, topical or parenteral administration, contain the above novel compounds and pharmaceutically acceptable carriers. The compositions have anti-phlogistic, analgesic, antianaphylactic and anti-pyretic activity.
GB1226727D 1968-06-28 1969-06-13 Expired GB1226727A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR157275A FR7492M (en) 1968-06-28 1968-06-28

Publications (1)

Publication Number Publication Date
GB1226727A true GB1226727A (en) 1971-03-31

Family

ID=8651875

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1226727D Expired GB1226727A (en) 1968-06-28 1969-06-13

Country Status (6)

Country Link
BE (1) BE734480A (en)
CH (1) CH510670A (en)
DE (1) DE1932485A1 (en)
ES (1) ES369188A1 (en)
FR (1) FR7492M (en)
GB (1) GB1226727A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004106306A1 (en) * 2003-05-30 2004-12-09 Aston University Novel ureido - and amido-pyrazolone derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004106306A1 (en) * 2003-05-30 2004-12-09 Aston University Novel ureido - and amido-pyrazolone derivatives

Also Published As

Publication number Publication date
ES369188A1 (en) 1971-05-16
BE734480A (en) 1969-11-17
FR7492M (en) 1969-12-08
DE1932485A1 (en) 1970-01-08
CH510670A (en) 1971-07-31

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Legal Events

Date Code Title Description
CSNS Application of which complete specification have been accepted and published, but patent is not sealed