GB1224064A - New 2-n-substituted carbamoyloxy-3-chloro-1-propargyloxy propanes and their process of preparation - Google Patents

New 2-n-substituted carbamoyloxy-3-chloro-1-propargyloxy propanes and their process of preparation

Info

Publication number
GB1224064A
GB1224064A GB4493268A GB4493268A GB1224064A GB 1224064 A GB1224064 A GB 1224064A GB 4493268 A GB4493268 A GB 4493268A GB 4493268 A GB4493268 A GB 4493268A GB 1224064 A GB1224064 A GB 1224064A
Authority
GB
United Kingdom
Prior art keywords
chloro
propanes
propargyloxy
preparation
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4493268A
Inventor
Claude Fauran
Claude Gouret
Guy Raynaud
Colette Douzon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to GB4493268A priority Critical patent/GB1224064A/en
Priority to FR6928485A priority patent/FR2018477B1/fr
Publication of GB1224064A publication Critical patent/GB1224064A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28—Nitrogen atoms
    • C07D295/32—Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1,224,064. Propargyloxypropane derivatives. DELALANDE S.A. 14 Aug., 1969 [20 Sept., 1968], No. 44932/68. Heading C2C. Novel compounds (I) in which Ar is (1) aryl, optionally substituted by 1-4C aliphatic radical, halo, CF 3 , alkoxy, alkenyloxy, alkylenoxy, OH, COOH or alkoxycarbonyl; (2) araliphatic radical; or (3) heterocyclyl; are prepared by reaction of the appropriate amine ArNH 2 with 2-chloroformyloxy-3- chloro-1-propargyloxypropane. Pharmaceutical compositions comprise a compound (I) together with a suitable carrier and are administered orally, rectally or topically. They exhibit tranquillizing, sedative, myorelaxant, analgesic and excitative properties.
GB4493268A 1968-09-20 1968-09-20 New 2-n-substituted carbamoyloxy-3-chloro-1-propargyloxy propanes and their process of preparation Expired GB1224064A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB4493268A GB1224064A (en) 1968-09-20 1968-09-20 New 2-n-substituted carbamoyloxy-3-chloro-1-propargyloxy propanes and their process of preparation
FR6928485A FR2018477B1 (en) 1968-09-20 1969-08-20

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4493268A GB1224064A (en) 1968-09-20 1968-09-20 New 2-n-substituted carbamoyloxy-3-chloro-1-propargyloxy propanes and their process of preparation

Publications (1)

Publication Number Publication Date
GB1224064A true GB1224064A (en) 1971-03-03

Family

ID=10435281

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4493268A Expired GB1224064A (en) 1968-09-20 1968-09-20 New 2-n-substituted carbamoyloxy-3-chloro-1-propargyloxy propanes and their process of preparation

Country Status (2)

Country Link
FR (1) FR2018477B1 (en)
GB (1) GB1224064A (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131911C (en) * 1965-07-27

Also Published As

Publication number Publication date
FR2018477A1 (en) 1970-05-29
FR2018477B1 (en) 1973-06-08

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