GB1214409A - Novel pyrazine derivatives and their preparation - Google Patents

Novel pyrazine derivatives and their preparation

Info

Publication number
GB1214409A
GB1214409A GB53830/69A GB5383069A GB1214409A GB 1214409 A GB1214409 A GB 1214409A GB 53830/69 A GB53830/69 A GB 53830/69A GB 5383069 A GB5383069 A GB 5383069A GB 1214409 A GB1214409 A GB 1214409A
Authority
GB
United Kingdom
Prior art keywords
alkyl
phenyl
methyl
group
diamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB53830/69A
Other languages
English (en)
Inventor
Edward Jethro Gragoe Jr
Kenneth Leroy Shepard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1214409A publication Critical patent/GB1214409A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GB53830/69A 1967-09-07 1968-09-03 Novel pyrazine derivatives and their preparation Expired GB1214409A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66600467A 1967-09-07 1967-09-07
US71897668A 1968-03-21 1968-03-21

Publications (1)

Publication Number Publication Date
GB1214409A true GB1214409A (en) 1970-12-02

Family

ID=27099350

Family Applications (2)

Application Number Title Priority Date Filing Date
GB41777/68A Expired GB1214408A (en) 1967-09-07 1968-09-03 3,5-diamino-6-halo-pyrazinamide derivatives
GB53830/69A Expired GB1214409A (en) 1967-09-07 1968-09-03 Novel pyrazine derivatives and their preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB41777/68A Expired GB1214408A (en) 1967-09-07 1968-09-03 3,5-diamino-6-halo-pyrazinamide derivatives

Country Status (15)

Country Link
AT (1) AT289123B (es)
BE (1) BE720233A (es)
CA (1) CA939345A (es)
CH (1) CH534168A (es)
DK (1) DK145892C (es)
ES (1) ES357877A1 (es)
FI (1) FI50975C (es)
FR (1) FR8490M (es)
GB (2) GB1214408A (es)
IL (1) IL30634A0 (es)
NL (1) NL6812003A (es)
NO (1) NO125678B (es)
OA (1) OA02886A (es)
SE (1) SE355811B (es)
YU (2) YU205268A (es)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013064451A1 (en) * 2011-11-02 2013-05-10 Boehringer Ingelheim International Gmbh Novel process for the preparation of acylguanidines and acylthioureas
US8759349B2 (en) 2011-11-02 2014-06-24 Boehringer Ingelheim International Gmbh Heterocyclic compounds, medicaments containing said compounds, use thereof and processes for the preparation thereof
US8841309B2 (en) 2012-09-24 2014-09-23 Boehringer Ingelheim International Gmbh Substituted pyrazines and their use in the treatment of disease
US8859559B2 (en) 2011-12-20 2014-10-14 Boehringer Ingelheim International Gmbh Substituted pyrazines and their use in the treatment of disease
US9078909B2 (en) 2012-05-25 2015-07-14 Boehringer Ingelheim International Gmbh Tertiary amines, medicaments containing said amines, use thereof and processes for the preparation thereof

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013064451A1 (en) * 2011-11-02 2013-05-10 Boehringer Ingelheim International Gmbh Novel process for the preparation of acylguanidines and acylthioureas
US8759349B2 (en) 2011-11-02 2014-06-24 Boehringer Ingelheim International Gmbh Heterocyclic compounds, medicaments containing said compounds, use thereof and processes for the preparation thereof
US8791260B2 (en) 2011-11-02 2014-07-29 Boehringer Ingelheim International Gmbh Process for the preparation of acylguanidines and acylthioureas
CN104024231A (zh) * 2011-11-02 2014-09-03 勃林格殷格翰国际有限公司 制备酰基胍和酰基硫脲化合物的新方法
US9920035B2 (en) 2011-11-02 2018-03-20 Boehringer Ingelheim International Gmbh Heterocyclic compounds, medicaments containing said compounds, use thereof and processes for the preparation thereof
US8859559B2 (en) 2011-12-20 2014-10-14 Boehringer Ingelheim International Gmbh Substituted pyrazines and their use in the treatment of disease
US9078909B2 (en) 2012-05-25 2015-07-14 Boehringer Ingelheim International Gmbh Tertiary amines, medicaments containing said amines, use thereof and processes for the preparation thereof
US8841309B2 (en) 2012-09-24 2014-09-23 Boehringer Ingelheim International Gmbh Substituted pyrazines and their use in the treatment of disease

Also Published As

Publication number Publication date
YU205268A (en) 1978-06-30
ES357877A1 (es) 1970-05-01
IL30634A0 (en) 1968-10-24
GB1214408A (en) 1970-12-02
DK145892C (da) 1983-09-12
NL6812003A (es) 1969-03-11
YU34082B (en) 1978-12-31
FR8490M (es) 1973-07-27
SE355811B (es) 1973-05-07
FI50975B (es) 1976-05-31
DK145892B (da) 1983-04-05
CH534168A (de) 1973-02-28
BE720233A (es) 1969-02-28
CA939345A (en) 1974-01-01
OA02886A (fr) 1970-12-15
FI50975C (fi) 1976-09-10
AT289123B (de) 1971-04-13
NO125678B (es) 1972-10-16

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Legal Events

Date Code Title Description
CSNS Application of which complete specification have been accepted and published, but patent is not sealed