GB1206790A - Organo-silicon complexes and preparation thereof - Google Patents
Organo-silicon complexes and preparation thereofInfo
- Publication number
- GB1206790A GB1206790A GB5777467A GB5777467A GB1206790A GB 1206790 A GB1206790 A GB 1206790A GB 5777467 A GB5777467 A GB 5777467A GB 5777467 A GB5777467 A GB 5777467A GB 1206790 A GB1206790 A GB 1206790A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- compounds
- anion
- pharmaceutical
- dec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001450 anions Chemical class 0.000 abstract 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- AEMOLEFTQBMNLQ-VANFPWTGSA-N D-mannopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H]1O AEMOLEFTQBMNLQ-VANFPWTGSA-N 0.000 abstract 2
- 239000002537 cosmetic Substances 0.000 abstract 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 abstract 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 abstract 2
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000001962 electrophoresis Methods 0.000 abstract 1
- 239000006260 foam Substances 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 238000007918 intramuscular administration Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000006210 lotion Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000002894 organic compounds Chemical class 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 150000003961 organosilicon compounds Chemical class 0.000 abstract 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 229960004889 salicylic acid Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 229960005322 streptomycin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0834—Compounds having one or more O-Si linkage
- C07F7/0836—Compounds with one or more Si-OH or Si-O-metal linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Birds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
1,206,790. Pharmaceutical and cosmetic compositions comprising organosilicon compounds. C. H. J. GUEYNE and M. I. DUFFAUT. 20 Dec., 1967 [23 Dec., 1966 (2)], No. 5.7774/67. Addition to 955969. Heading A5B. [Also in Division C3] Pharmaceutical and cosmetic compositions comprise as active ingredient an organosilicon complex of the general formula in which R is an organic group, other than an acid or salt thereof, which may contain functional groups, x is 0 to 3, Y is the anion of a mineral or organic acid or of any salt-forming organic compound that affords an anion. Me is sodium or potassium, and a, b and c are finite numbers. Examples of these compounds are CH 3 Si(OH) 3 .C 7 H 5 O 3 Na, Y being derived from salicylic acid; CH 3 Si (OH) 3 .C 6 H 9 O 7 Na, Y being derived from mannuronic acid; and similar compounds in which the anion is from citric acid and phenol. The compounds may be used in aqueous solution and may be used in admixture with an antibiotic, e.g. penicillin or streptomycin. The mannuronate derivative is particularly useful in creams, lotions, milks or foam baths. The pharmaceutical preparations may be applied by intramuscular, intravenous, oral, rectal or percutaneal methods or by electrophoresis. The compositions may be used as eyebaths and in application pads and are stated to be effective against a variety of diseases.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR88728A FR6871M (en) | 1966-12-23 | 1966-12-23 | |
| FR88729A FR92263E (en) | 1959-05-12 | 1966-12-23 | Manufacturing process of organo-silicic complexes, complexes obtained and their applications |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1206790A true GB1206790A (en) | 1970-09-30 |
Family
ID=26174421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5777467A Expired GB1206790A (en) | 1966-12-23 | 1967-12-20 | Organo-silicon complexes and preparation thereof |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE708383A (en) |
| CA (1) | CA922703A (en) |
| CH (1) | CH488736A (en) |
| DE (1) | DE1668171A1 (en) |
| DK (2) | DK131503B (en) |
| GB (1) | GB1206790A (en) |
| NO (1) | NO127402B (en) |
| SE (1) | SE349046B (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1985003434A1 (en) * | 1984-02-06 | 1985-08-15 | Neutrogena Corporation | Vehicle for delivering active pharmaceutical ingredientsto the h uman skin |
| GB2159408A (en) * | 1984-03-30 | 1985-12-04 | Lion Corp | Humectant |
| US4563347A (en) * | 1982-05-20 | 1986-01-07 | Dow Corning Corporation | Compositions used to condition hair |
| US4784844A (en) * | 1979-12-03 | 1988-11-15 | General Electric Company | Volatile silicone-water emulsions and methods of preparation and use |
| EP1468693A2 (en) * | 1993-12-10 | 2004-10-20 | Merrell Pharmaceuticals Inc. | Use of 2,6-di -alkyl-4-silyl-phenols for treating diabetes mellitus |
| WO2008084268A1 (en) | 2007-01-11 | 2008-07-17 | Mta Szegedi Biológiai Központ | Use of biglycan or enhancers of biglycan activity in the preparation of pharmaceutical compositions |
| EP3666249A1 (en) | 2018-12-10 | 2020-06-17 | Jednostka Innowacyjno-Wdrozeniowa INWEX Spolka z Ograniczona odpowiedzialnoscia | Complexes of organic silicon compounds with boron citrate and dimethylethanolamine |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2510407A1 (en) * | 1981-07-28 | 1983-02-04 | Duffaut Charles | Organo-silanol and adenosine phosphoric acid deriv. compsn. - for cellulitis treatment by ionokinesis, opt. contain organic acids |
| BE1023898B1 (en) | 2016-08-25 | 2017-09-07 | Sil'innov Scrl | Composition comprising silicon and its method of preparation |
-
1967
- 1967-12-19 SE SE1745167A patent/SE349046B/xx unknown
- 1967-12-20 GB GB5777467A patent/GB1206790A/en not_active Expired
- 1967-12-21 CA CA008267A patent/CA922703A/en not_active Expired
- 1967-12-21 BE BE708383D patent/BE708383A/xx not_active IP Right Cessation
- 1967-12-22 NO NO17112067A patent/NO127402B/no unknown
- 1967-12-22 DE DE19671668171 patent/DE1668171A1/en active Pending
- 1967-12-22 DK DK649467A patent/DK131503B/en unknown
- 1967-12-27 CH CH1819767A patent/CH488736A/en not_active IP Right Cessation
-
1970
- 1970-03-12 DK DK122670A patent/DK126234B/en not_active IP Right Cessation
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4784844A (en) * | 1979-12-03 | 1988-11-15 | General Electric Company | Volatile silicone-water emulsions and methods of preparation and use |
| US4563347A (en) * | 1982-05-20 | 1986-01-07 | Dow Corning Corporation | Compositions used to condition hair |
| WO1985003434A1 (en) * | 1984-02-06 | 1985-08-15 | Neutrogena Corporation | Vehicle for delivering active pharmaceutical ingredientsto the h uman skin |
| US4678663A (en) * | 1984-02-06 | 1987-07-07 | Nuetrogena Corporation | Hydroquinone composition having enhanced bio-availability and percutaneous adsorption |
| GB2159408A (en) * | 1984-03-30 | 1985-12-04 | Lion Corp | Humectant |
| EP1468693A2 (en) * | 1993-12-10 | 2004-10-20 | Merrell Pharmaceuticals Inc. | Use of 2,6-di -alkyl-4-silyl-phenols for treating diabetes mellitus |
| EP1468693A3 (en) * | 1993-12-10 | 2004-11-03 | Merrell Pharmaceuticals Inc. | Use of 2,6-di -alkyl-4-silyl-phenols for treating diabetes mellitus |
| WO2008084268A1 (en) | 2007-01-11 | 2008-07-17 | Mta Szegedi Biológiai Központ | Use of biglycan or enhancers of biglycan activity in the preparation of pharmaceutical compositions |
| CN101631552B (en) * | 2007-01-11 | 2013-08-07 | 匈牙利制药2000有限公司 | Use of biglycan or enhancers of biglycan activity in the preparation of pharmaceutical compositions |
| EP3666249A1 (en) | 2018-12-10 | 2020-06-17 | Jednostka Innowacyjno-Wdrozeniowa INWEX Spolka z Ograniczona odpowiedzialnoscia | Complexes of organic silicon compounds with boron citrate and dimethylethanolamine |
Also Published As
| Publication number | Publication date |
|---|---|
| CH488736A (en) | 1970-04-15 |
| DK131503C (en) | 1975-12-29 |
| SE349046B (en) | 1972-09-18 |
| CA922703A (en) | 1973-03-13 |
| DK126234B (en) | 1973-06-25 |
| DE1668171A1 (en) | 1974-08-29 |
| NO127402B (en) | 1973-06-18 |
| BE708383A (en) | 1968-05-02 |
| DK131503B (en) | 1975-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 435 | Patent endorsed 'licences of right' on the date specified (sect. 35/1949) | ||
| PE | Patent expired |