GB1202500A - Substituted phenylacetonitriles - Google Patents
Substituted phenylacetonitrilesInfo
- Publication number
- GB1202500A GB1202500A GB5517369A GB5517369A GB1202500A GB 1202500 A GB1202500 A GB 1202500A GB 5517369 A GB5517369 A GB 5517369A GB 5517369 A GB5517369 A GB 5517369A GB 1202500 A GB1202500 A GB 1202500A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- group
- reacted
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000007962 benzene acetonitriles Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 12
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- -1 methylenedioxy group Chemical group 0.000 abstract 2
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,202,500. Substituted phenylacetonitriles. KNOLL A.G. CHEMISCHE FABRIKEN. 8 Dec., 1967, No. 55173/69. Heading C2C. Novel compounds of Formula I wherein at least of A, B, C, A<SP>1</SP>, B<SP>1</SP> or C<SP>1</SP> is a benzyloxy group, the remainder being H or halogen atoms, C 1-8 alkyl or C 1-8 alkoxy groups or two adjacent groups may together form a methylenedioxy group, Y is a straight or branched chain alkylene group of 2 to 8 carbon atoms and having 2 to 4 carbon atoms in the main chain, Z is a straight or branched chain alkylene group of 1 to 8 carbon atoms and having 1 to 3 carbon atoms in the main chain, R is C 1-8 alkyl and R 1 is a C 1-8 alkyl group or a group of formula wherein A<SP>11</SP>, B<SP>11</SP>,and C<SP>11</SP> are each H, halogen, C 1-8 alkyl, C 1-8 alkoxy or two adjacent groups may together form a methylenedioxy group and n is 0 or 1, are prepared by one of the following methods: (a) a compound of formula is reacted with a compound of Formula III where X is a reactive acid radical; (b) a compound of formula is reacted with a compound of formula R 1 -X; (c) a compound of formula is reacted with a compound of Formula III above and then with a compound of formula R 1 - X; (d) a compound of formula in reacted with a compound of formula and (e) a compound of Formula I above wherein R is H is alkylated. The novel compounds have coronary activity and find use as medicaments.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5517369A GB1202500A (en) | 1967-12-08 | 1967-12-08 | Substituted phenylacetonitriles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5517369A GB1202500A (en) | 1967-12-08 | 1967-12-08 | Substituted phenylacetonitriles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1202500A true GB1202500A (en) | 1970-08-19 |
Family
ID=10473177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5517369A Expired GB1202500A (en) | 1967-12-08 | 1967-12-08 | Substituted phenylacetonitriles |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1202500A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4438131A (en) | 1981-04-10 | 1984-03-20 | Basf Aktiengesellschaft | Ω-Cyano-1, Ω-diphenyl-azaalkane derivatives, their preparation and drugs containing them |
-
1967
- 1967-12-08 GB GB5517369A patent/GB1202500A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4438131A (en) | 1981-04-10 | 1984-03-20 | Basf Aktiengesellschaft | Ω-Cyano-1, Ω-diphenyl-azaalkane derivatives, their preparation and drugs containing them |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |