GB1200483A - Method and intermediates for producing indole derivatives - Google Patents
Method and intermediates for producing indole derivativesInfo
- Publication number
- GB1200483A GB1200483A GB939467A GB939467A GB1200483A GB 1200483 A GB1200483 A GB 1200483A GB 939467 A GB939467 A GB 939467A GB 939467 A GB939467 A GB 939467A GB 1200483 A GB1200483 A GB 1200483A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- indole derivatives
- hydrogen
- alkyl group
- intermediates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title abstract 3
- 150000002475 indoles Chemical class 0.000 title abstract 3
- 239000000543 intermediate Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000000242 4-chlorobenzoyl group Chemical group ClC1=CC=C(C(=O)*)C=C1 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- SIKJAQJRHWYJAI-UHFFFAOYSA-N benzopyrrole Natural products C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 1
- 238000010531 catalytic reduction reaction Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- -1 hydroxy, amino Chemical group 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 229930192474 thiophene Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939467A GB1200483A (en) | 1967-02-28 | 1967-02-28 | Method and intermediates for producing indole derivatives |
| IL2950268A IL29502A (en) | 1967-02-28 | 1968-02-20 | The production of 1-benzoyl-3-indoleacetic acid derivatives and new thieno(3,4-b)indoles |
| DE19681670031 DE1670031A1 (de) | 1967-02-28 | 1968-02-26 | Verfahren und Zwischenprodukte zur Herstellung von Indolderivaten |
| NL6802698A NL6802698A (enrdf_load_stackoverflow) | 1967-02-28 | 1968-02-26 | |
| SE244668A SE333732B (enrdf_load_stackoverflow) | 1967-02-28 | 1968-02-26 | |
| BE711306D BE711306A (enrdf_load_stackoverflow) | 1967-02-28 | 1968-02-26 | |
| NO70868A NO123386B (enrdf_load_stackoverflow) | 1967-02-28 | 1968-02-27 | |
| CH278968A CH507237A (de) | 1967-02-28 | 1968-02-27 | Verfahren zur Herstellung von Indol-Derivaten |
| AT188568A AT285597B (de) | 1967-02-28 | 1968-02-27 | Verfahren zur Herstellung von Indolderivaten |
| ES351012A ES351012A1 (es) | 1967-02-28 | 1968-02-27 | Un metodo de produccion de derivados de inodol. |
| AT01410/69A AT287689B (de) | 1967-02-28 | 1968-02-27 | Verfahren zur herstellung von neuen thiophenderivaten |
| FR141585A FR1555227A (enrdf_load_stackoverflow) | 1967-02-28 | 1968-02-28 | |
| FR153144A FR7620M (enrdf_load_stackoverflow) | 1967-02-28 | 1968-05-28 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939467A GB1200483A (en) | 1967-02-28 | 1967-02-28 | Method and intermediates for producing indole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1200483A true GB1200483A (en) | 1970-07-29 |
Family
ID=9871139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB939467A Expired GB1200483A (en) | 1967-02-28 | 1967-02-28 | Method and intermediates for producing indole derivatives |
Country Status (11)
-
1967
- 1967-02-28 GB GB939467A patent/GB1200483A/en not_active Expired
-
1968
- 1968-02-20 IL IL2950268A patent/IL29502A/xx unknown
- 1968-02-26 BE BE711306D patent/BE711306A/xx unknown
- 1968-02-26 DE DE19681670031 patent/DE1670031A1/de active Pending
- 1968-02-26 NL NL6802698A patent/NL6802698A/xx unknown
- 1968-02-26 SE SE244668A patent/SE333732B/xx unknown
- 1968-02-27 AT AT01410/69A patent/AT287689B/de not_active IP Right Cessation
- 1968-02-27 CH CH278968A patent/CH507237A/de not_active IP Right Cessation
- 1968-02-27 AT AT188568A patent/AT285597B/de not_active IP Right Cessation
- 1968-02-27 ES ES351012A patent/ES351012A1/es not_active Expired
- 1968-02-27 NO NO70868A patent/NO123386B/no unknown
- 1968-02-28 FR FR141585A patent/FR1555227A/fr not_active Expired
- 1968-05-28 FR FR153144A patent/FR7620M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE711306A (enrdf_load_stackoverflow) | 1968-07-01 |
| AT285597B (de) | 1970-11-10 |
| CH507237A (de) | 1971-05-15 |
| SE333732B (enrdf_load_stackoverflow) | 1971-03-29 |
| NO123386B (enrdf_load_stackoverflow) | 1971-11-08 |
| AT287689B (de) | 1971-02-10 |
| DE1670031A1 (de) | 1971-02-25 |
| FR1555227A (enrdf_load_stackoverflow) | 1969-01-24 |
| NL6802698A (enrdf_load_stackoverflow) | 1968-08-29 |
| IL29502A (en) | 1971-10-20 |
| ES351012A1 (es) | 1969-05-16 |
| FR7620M (enrdf_load_stackoverflow) | 1970-01-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |