GB1199613A - Process for Producing 2-Amino-4-Substituted Butyric Acids and their Corresponding Nitriles - Google Patents

Process for Producing 2-Amino-4-Substituted Butyric Acids and their Corresponding Nitriles

Info

Publication number
GB1199613A
GB1199613A GB4668967A GB4668967A GB1199613A GB 1199613 A GB1199613 A GB 1199613A GB 4668967 A GB4668967 A GB 4668967A GB 4668967 A GB4668967 A GB 4668967A GB 1199613 A GB1199613 A GB 1199613A
Authority
GB
United Kingdom
Prior art keywords
amino
butyric acids
formula
producing
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4668967A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Publication of GB1199613A publication Critical patent/GB1199613A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,199,613. Production of derivatives of 2- amino-4-substituted-butyric acids. NIPPON KAYAKU K.K. 12 Oct., 1967 [12 Oct., 1966 (2)], No. 46689/67. Heading C2C. Compounds of the formula wherein R is an alkyl group, which may be prepared by reacting a compound of the formula with hydrogen cyanide or salts thereof and ammonia, may subsequently be hydrolysed to give compounds of the formula wherein R<SP>1</SP> is hydrogen or an alkyl radical. The reaction for producing the nitrile may be effected in an aqueous solution or aqueous organic solvent under ambient or elevated temperature and pressure conditions. For the subsequent hydrolysis reaction the nitrile may be separated from the reaction mixture or it may be hydrolysed in situ with conventional acids or alkalis to form the 2-amino-4-alkoxy- or -hydroxy-butyric acids. Further 2-amino-4- hydroxybutyric acid may also be obtained by hydrolysing the 2-amino-4-alkoxy-butyric acids with hydrochloric or sulphuric acid. Specific examples are given in which the radicals R and R<SP>1</SP> (when alkyl) are methyl, ethyl, propyl and butyl.
GB4668967A 1966-10-12 1967-10-12 Process for Producing 2-Amino-4-Substituted Butyric Acids and their Corresponding Nitriles Expired GB1199613A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6663766 1966-10-12
JP6831766 1966-10-19

Publications (1)

Publication Number Publication Date
GB1199613A true GB1199613A (en) 1970-07-22

Family

ID=26407832

Family Applications (2)

Application Number Title Priority Date Filing Date
GB2812769A Expired GB1199614A (en) 1966-10-12 1967-10-12 Process for Producing 2-Amino-4-Substituted Butyric Acids and the Corresponding Hydantoins
GB4668967A Expired GB1199613A (en) 1966-10-12 1967-10-12 Process for Producing 2-Amino-4-Substituted Butyric Acids and their Corresponding Nitriles

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB2812769A Expired GB1199614A (en) 1966-10-12 1967-10-12 Process for Producing 2-Amino-4-Substituted Butyric Acids and the Corresponding Hydantoins

Country Status (2)

Country Link
DE (1) DE1643480A1 (en)
GB (2) GB1199614A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2217706A (en) * 1988-07-07 1989-11-01 W A Gibbons alpha -Amino-alkanoic acid derivatives and process for their preparation with anti-inflammatory, analgesic, sedative, hypnotic, anxiolytic, spasmolytic, anaesthetic, muscle relaxant and cardiovascular activity

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601674B1 (en) * 1986-07-17 1988-09-23 Aec Chim Organ Biolog PROCESS FOR THE PREPARATION OF AN AQUEOUS SOLUTION OF METHIONINE SODIUM SALT

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2217706A (en) * 1988-07-07 1989-11-01 W A Gibbons alpha -Amino-alkanoic acid derivatives and process for their preparation with anti-inflammatory, analgesic, sedative, hypnotic, anxiolytic, spasmolytic, anaesthetic, muscle relaxant and cardiovascular activity

Also Published As

Publication number Publication date
DE1643480A1 (en) 1972-02-17
GB1199614A (en) 1970-07-22

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees