GB1197326A - Pyrazino[1,2-a]Quinolines and Process for Preparing Same - Google Patents
Pyrazino[1,2-a]Quinolines and Process for Preparing SameInfo
- Publication number
- GB1197326A GB1197326A GB45005/67A GB4500567A GB1197326A GB 1197326 A GB1197326 A GB 1197326A GB 45005/67 A GB45005/67 A GB 45005/67A GB 4500567 A GB4500567 A GB 4500567A GB 1197326 A GB1197326 A GB 1197326A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrazino
- quinolines
- aromatic ring
- aliphatic
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FXNGILFJMJFFBM-UHFFFAOYSA-N 1h-pyrazino[1,2-a]quinoline Chemical class C1=CC=C2N3CC=NC=C3C=CC2=C1 FXNGILFJMJFFBM-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- CHIINPDGHUONJZ-UHFFFAOYSA-N 2,3,4,4a,5,6-hexahydro-1h-pyrazino[1,2-a]quinoline Chemical class C1=CC=C2N3CCNCC3CCC2=C1 CHIINPDGHUONJZ-UHFFFAOYSA-N 0.000 abstract 1
- KVIOIFKWKBDGAV-UHFFFAOYSA-N 58881-41-7 Chemical compound C1=CC=C2N3C(=O)C4=CC5=CC=CC=C5N4C(=O)C3=CC2=C1 KVIOIFKWKBDGAV-UHFFFAOYSA-N 0.000 abstract 1
- 101100188552 Arabidopsis thaliana OCT3 gene Proteins 0.000 abstract 1
- -1 CF 3 Chemical group 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 230000002908 adrenolytic effect Effects 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- SMWDFEZZVXVKRB-UHFFFAOYSA-N anhydrous quinoline Natural products N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 229940111121 antirheumatic drug quinolines Drugs 0.000 abstract 1
- 150000001728 carbonyl compounds Chemical class 0.000 abstract 1
- 238000006264 debenzylation reaction Methods 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- LMKOGFPNETZZTE-UHFFFAOYSA-N pyrido[2,3-f]quinoxaline Chemical class C1=CN=C2C3=NC=CC=C3C=CC2=N1 LMKOGFPNETZZTE-UHFFFAOYSA-N 0.000 abstract 1
- 150000003248 quinolines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1436366A CH493546A (de) | 1966-10-05 | 1966-10-05 | Verfahren zur Herstellung neuer Pyrazino (1,2-a)-chinoline |
| CH156167 | 1967-02-02 | ||
| CH1136467 | 1967-08-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1197326A true GB1197326A (en) | 1970-07-01 |
Family
ID=27173077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB45005/67A Expired GB1197326A (en) | 1966-10-05 | 1967-10-03 | Pyrazino[1,2-a]Quinolines and Process for Preparing Same |
Country Status (7)
| Country | Link |
|---|---|
| AT (2) | AT274812B (xx) |
| BE (1) | BE704692A (xx) |
| DE (1) | DE1670470A1 (xx) |
| ES (1) | ES345737A1 (xx) |
| FR (3) | FR1549375A (xx) |
| GB (1) | GB1197326A (xx) |
| NL (1) | NL6713505A (xx) |
-
1967
- 1967-09-27 DE DE19671670470 patent/DE1670470A1/de active Pending
- 1967-10-03 FR FR1549375D patent/FR1549375A/fr not_active Expired
- 1967-10-03 GB GB45005/67A patent/GB1197326A/en not_active Expired
- 1967-10-04 AT AT900967A patent/AT274812B/de active
- 1967-10-04 NL NL6713505A patent/NL6713505A/xx unknown
- 1967-10-04 AT AT900867A patent/AT275526B/de active
- 1967-10-04 BE BE704692D patent/BE704692A/xx unknown
- 1967-10-04 ES ES345737A patent/ES345737A1/es not_active Expired
- 1967-12-29 FR FR134281A patent/FR7111M/fr not_active Expired
- 1967-12-29 FR FR134280A patent/FR7110M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1670470A1 (de) | 1971-02-11 |
| AT275526B (de) | 1969-10-27 |
| ES345737A1 (es) | 1969-01-16 |
| FR1549375A (xx) | 1968-12-13 |
| BE704692A (xx) | 1968-04-04 |
| NL6713505A (xx) | 1968-04-08 |
| FR7111M (xx) | 1969-07-15 |
| FR7110M (xx) | 1969-07-15 |
| AT274812B (de) | 1969-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |