GB1195933A - Substituted Benzothiadiazepine Derivatives and the Manufacture thereof - Google Patents
Substituted Benzothiadiazepine Derivatives and the Manufacture thereofInfo
- Publication number
- GB1195933A GB1195933A GB24466/68A GB2446668A GB1195933A GB 1195933 A GB1195933 A GB 1195933A GB 24466/68 A GB24466/68 A GB 24466/68A GB 2446668 A GB2446668 A GB 2446668A GB 1195933 A GB1195933 A GB 1195933A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzoyl
- prepared
- guanidine
- alkyl
- benzothiadiazepine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KAOYLRLQZXRRBD-UHFFFAOYSA-N 1,2,3-benzothiadiazepine Chemical class S1N=NC=CC2=CC=CC=C12 KAOYLRLQZXRRBD-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- BPSHNCPJAOFFQB-UHFFFAOYSA-N 2-benzoyl-4-chlorobenzenesulfonyl chloride Chemical compound ClC1=CC=C(S(Cl)(=O)=O)C(C(=O)C=2C=CC=CC=2)=C1 BPSHNCPJAOFFQB-UHFFFAOYSA-N 0.000 abstract 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- 125000005036 alkoxyphenyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 2
- 238000005984 hydrogenation reaction Methods 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- FHPWVYWEPHZNLT-UHFFFAOYSA-N 1lambda6,2,4-benzothiadiazepine 1,1-dioxide Chemical class S1(N=CN=CC2=C1C=CC=C2)(=O)=O FHPWVYWEPHZNLT-UHFFFAOYSA-N 0.000 abstract 1
- ZJPLUAAEPREROD-UHFFFAOYSA-N 2-(2-benzoyl-4-chlorophenyl)sulfonylguanidine Chemical compound NC(N)=NS(=O)(=O)C1=CC=C(Cl)C=C1C(=O)C1=CC=CC=C1 ZJPLUAAEPREROD-UHFFFAOYSA-N 0.000 abstract 1
- WHJGMXCAZTYNOL-UHFFFAOYSA-N 2-benzoylbenzenesulfonyl chloride Chemical compound ClS(=O)(=O)C1=CC=CC=C1C(=O)C1=CC=CC=C1 WHJGMXCAZTYNOL-UHFFFAOYSA-N 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 150000001409 amidines Chemical class 0.000 abstract 1
- 239000003849 aromatic solvent Substances 0.000 abstract 1
- PXXJHWLDUBFPOL-UHFFFAOYSA-N benzamidine Chemical compound NC(=N)C1=CC=CC=C1 PXXJHWLDUBFPOL-UHFFFAOYSA-N 0.000 abstract 1
- LZCZIHQBSCVGRD-UHFFFAOYSA-N benzenecarboximidamide;hydron;chloride Chemical compound [Cl-].NC(=[NH2+])C1=CC=CC=C1 LZCZIHQBSCVGRD-UHFFFAOYSA-N 0.000 abstract 1
- STIAPHVBRDNOAJ-UHFFFAOYSA-N carbamimidoylazanium;carbonate Chemical compound NC(N)=N.NC(N)=N.OC(O)=O STIAPHVBRDNOAJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000007859 condensation product Substances 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- -1 morpholino, piperidino Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/36—Seven-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64822667A | 1967-06-23 | 1967-06-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1195933A true GB1195933A (en) | 1970-06-24 |
Family
ID=24599924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB24466/68A Expired GB1195933A (en) | 1967-06-23 | 1968-05-22 | Substituted Benzothiadiazepine Derivatives and the Manufacture thereof |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3671528A (xx) |
| BE (1) | BE716945A (xx) |
| FR (1) | FR1571016A (xx) |
| GB (1) | GB1195933A (xx) |
| IL (1) | IL30009A (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3516616A1 (de) * | 1984-08-30 | 1986-03-13 | Bayer Ag, 5090 Leverkusen | Benzodisultame |
| DE3517845A1 (de) * | 1985-05-17 | 1986-11-20 | Bayer Ag, 5090 Leverkusen | Benzolactamsultame |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3051727A (en) * | 1962-08-28 | S-dihydro-l | ||
| US1915334A (en) * | 1930-10-16 | 1933-06-27 | Du Pont | Fluosilicate of organic heterocyclic bases and process of making it |
| US3163644A (en) * | 1959-10-16 | 1964-12-29 | Ciba Geigy Corp | Derivatives of 2-h-1, 2, 4-benzo thiadiazine-1, 1-dioxide |
| US3090783A (en) * | 1962-06-12 | 1963-05-21 | Olin Mathieson | Dihydrobenzothiadiazines |
| US3203954A (en) * | 1963-07-15 | 1965-08-31 | Upjohn Co | Novel 3, 5-disubstituted-1, 2, 6-(2h)-thiadiazine-1, 1-dioxides |
| US3377357A (en) * | 1966-06-27 | 1968-04-09 | Lilly Co Eli | 1, 2-benzothiazepine-1, 1-dioxides and their preparation |
| US3407198A (en) * | 1966-08-10 | 1968-10-22 | Upjohn Co | 2h-1, 2, 3-benzothiadiazine-1, 1-dioxides |
| US3464996A (en) * | 1967-05-16 | 1969-09-02 | Upjohn Co | 6h - dibenzo(c,g)(1,2,5)thiadiazocine - 5,5-dioxides and method for their production |
| US3526638A (en) * | 1967-10-05 | 1970-09-01 | Smithkline Corp | Substituted 3,4-dihydro-1h-2,1,5-benzothiadiazocine-2,2-dioxides |
-
1967
- 1967-06-23 US US648226A patent/US3671528A/en not_active Expired - Lifetime
-
1968
- 1968-05-16 IL IL30009A patent/IL30009A/xx unknown
- 1968-05-22 GB GB24466/68A patent/GB1195933A/en not_active Expired
- 1968-06-21 FR FR1571016D patent/FR1571016A/fr not_active Expired
- 1968-06-21 BE BE716945D patent/BE716945A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL30009A (en) | 1972-03-28 |
| IL30009A0 (en) | 1968-07-25 |
| BE716945A (xx) | 1968-12-23 |
| FR1571016A (xx) | 1969-06-13 |
| US3671528A (en) | 1972-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |