GB1194320A - Alkylation of Polyhydroxybenzophenones - Google Patents

Alkylation of Polyhydroxybenzophenones

Info

Publication number
GB1194320A
GB1194320A GB1737469A GB1737469A GB1194320A GB 1194320 A GB1194320 A GB 1194320A GB 1737469 A GB1737469 A GB 1737469A GB 1737469 A GB1737469 A GB 1737469A GB 1194320 A GB1194320 A GB 1194320A
Authority
GB
United Kingdom
Prior art keywords
hydroxy
alkyl
octyloxy
carboxy
april
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1737469A
Inventor
Martin Barry Bochner
Dale Edward Battin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of GB1194320A publication Critical patent/GB1194320A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

1,194,320. Benzophenone derivatives. AMERICAN CYANAMID CO. 2 April, 1969 [4 April, 1968], No. 17374/69. Heading C2C. Dimethylformamide, dimethylacetamide, tert.-butylformamide or dimethyl sulphoxide, or a mixture thereof, is used as a solvent in a process of making a benzophenone derivative of the formula in which R denotes a hydrogen or halogen atom or an alkyl, alkoxy, carboxy, carbalkoxy or hydroxy group, R 1 and R 2 denote hydrogen or halogen atoms or alkyl, alkoxy, carboxy or carbalkoxy groups and R 3 denotes an alkyl group, from a benzophenone derivative of the formula in which R, R 1 and R 2 are as defined above or one of R 1 and R 2 may be hydroxy. The process is effected by refluxing a reaction mixture containing an appropriate polyhydroxybenzophenone, an alkyl halide of 1-20 carbon atoms and an acid-binding agent in one of the specified solvents and recovering the alkylated product. The reaction may be catalysed by a metal bromide or iodide, and a small proportion of sodium hydrosulphite may be added to the product, before it is separated, to improve its colour. The examples describe the manufacture of 2-hydroxy-4-octyloxy-, 2,2<SP>1</SP>-dihydroxy - 4 - octyloxy -, 2 - hydroxy - 4 - methoxy-, 2 - hydroxy - 4 - dodecyloxy - 4<SP>1 </SP>- tert. - butyl and 2 - hydroxy - 4 - butoxy - benzophenones.
GB1737469A 1968-04-04 1969-04-02 Alkylation of Polyhydroxybenzophenones Expired GB1194320A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71893268A 1968-04-04 1968-04-04

Publications (1)

Publication Number Publication Date
GB1194320A true GB1194320A (en) 1970-06-10

Family

ID=24888143

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1737469A Expired GB1194320A (en) 1968-04-04 1969-04-02 Alkylation of Polyhydroxybenzophenones

Country Status (6)

Country Link
BE (1) BE730687A (en)
CH (1) CH510606A (en)
DE (1) DE1917409A1 (en)
FR (1) FR2005531A1 (en)
GB (1) GB1194320A (en)
NL (1) NL6904567A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112321407A (en) * 2020-10-29 2021-02-05 马鞍山科思化学有限公司 Novel process for preparing sunscreen agent 2-hydroxy-4-n-octoxy benzophenone

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3658910A (en) * 1970-02-11 1972-04-25 Carlisle Chemical Works Liquid 2-hydroxy-4-alkoxybenzophenones

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112321407A (en) * 2020-10-29 2021-02-05 马鞍山科思化学有限公司 Novel process for preparing sunscreen agent 2-hydroxy-4-n-octoxy benzophenone

Also Published As

Publication number Publication date
FR2005531A1 (en) 1969-12-12
CH510606A (en) 1971-07-31
BE730687A (en) 1969-09-29
NL6904567A (en) 1969-10-07
DE1917409A1 (en) 1969-11-13

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee