GB1192192A - Hematology Apparatus - Google Patents
Hematology ApparatusInfo
- Publication number
- GB1192192A GB1192192A GB28851/67A GB2885167A GB1192192A GB 1192192 A GB1192192 A GB 1192192A GB 28851/67 A GB28851/67 A GB 28851/67A GB 2885167 A GB2885167 A GB 2885167A GB 1192192 A GB1192192 A GB 1192192A
- Authority
- GB
- United Kingdom
- Prior art keywords
- stream
- quotient
- tube
- providing
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000005259 measurement Methods 0.000 abstract 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- RDYMFSUJUZBWLH-UHFFFAOYSA-N endosulfan Chemical compound C12COS(=O)OCC2C2(Cl)C(Cl)=C(Cl)C1(Cl)C2(Cl)Cl RDYMFSUJUZBWLH-UHFFFAOYSA-N 0.000 abstract 3
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
- G01N35/085—Flow Injection Analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/012—Red blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/016—White blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1024—Counting particles by non-optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1029—Particle size
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1486—Counting the particles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
- Y10T436/118339—Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
1,192,192. Determining blood characteristics. TECHNICON CORP. 22 June, 1967 [11 July, 1966], No. 28851/67. Heading B1X. Apparatus for determining blood characteristics comprises supply means 12 for providing an initial stream of the samples to be tested; means 30, 32, 34, 36 coupled to junction 20 for providing a plurality of quotient streams, each containing a fractional portion of each of the samples in the initial stream; first treating means coupled to tube 34 for treating one quotient stream for HCT analysis, first determining means for measuring the HCT for example by continuous measurement of the resistance of the stream by means of electrodes 54 and for providing a signal responsive to the HCT measurement; second treating means for treating another of the quotient streams for analysis and second determining means for making the appropriate measurement and providing a signal responsive to it; and recording means 132 for receiving the signals and recording in correlation the signals obtained by measurements on the fractional portions of a common sample of the initial stream. The quotient stream in tube 30 may be twice diluted with saline (at junctions 58 and 76) then passed through phaser coil 80 (see 1,183,631) to counter module 84 for RBC determination. The quotient stream in tube 32 may be lysed with water added at 107, mixed with ferricyanide-cyanide reagent at 116 to convert the haemoglobin to cyanomethaemoglobin and passed through phaser coil 121 to colorimeter 130 for HGB measurement. The quotient stream in tube 36 may be lysed with acetic acid and a surfactant added at 96, and passed through phaser coil 104 to counter module 84 for WBC determination. MCH, MCV and MCHC are calculated from the measured characteristics and all seven characteristics of the sample are printed out on a single document (Fig. 3 not shown). The circuit (Fig. 2 not shown) permits display of the measured characteristics in turn on a meter.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56429166A | 1966-07-11 | 1966-07-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1192192A true GB1192192A (en) | 1970-05-20 |
Family
ID=24253903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB28851/67A Expired GB1192192A (en) | 1966-07-11 | 1967-06-22 | Hematology Apparatus |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3427135A (en) |
| JP (1) | JPS512839B1 (en) |
| BE (1) | BE701133A (en) |
| CH (1) | CH475558A (en) |
| DE (1) | DE1673146C3 (en) |
| FR (1) | FR1529316A (en) |
| GB (1) | GB1192192A (en) |
| SE (1) | SE340190B (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE756423A (en) * | 1969-09-22 | 1971-03-22 | Technicon Instr | METHOD AND APPARATUS FOR THE AUTOMATIC DETERMINATION OF SAMPLES, IN PARTICULAR BLOOD SAMPLES |
| US3663175A (en) * | 1970-10-05 | 1972-05-16 | Bio Dynamics Inc | Method of determining hemoglobin in blood |
| US3741875A (en) * | 1970-10-30 | 1973-06-26 | Mount Sinai Res Foundation Inc | Process and apparatus for obtaining a differential white blood cell count |
| US3948605A (en) * | 1974-08-22 | 1976-04-06 | The Perkin-Elmer Corporation | Diluter for a kinetic analysis apparatus |
| US3948607A (en) * | 1974-08-22 | 1976-04-06 | The Perkin-Elmer Corporation | Transfer system for use in analysis apparatus |
| US4000974A (en) * | 1974-09-09 | 1977-01-04 | Beckman Instruments, Inc. | Sample residue cleaning system for biological analyzers |
| US4000973A (en) * | 1974-09-09 | 1977-01-04 | Beckman Instruments, Inc. | Sample residue cleaning system for biological analyzers |
| DK150802C (en) * | 1974-09-16 | 1988-02-01 | Bifok Ab | METHOD AND APPARATUS FOR CONTINUOUS HIGH-SPEED ANALYSIS OF A LIQUID TEST IN A BEARING FLOW |
| SE427503B (en) * | 1976-09-15 | 1983-04-11 | Bifok Ab | SET TO ANALYZE A SAMPLE BY FLOW-INJECTION ANALYSIS, BY CONTINUOUS DETERMINATION OF IONES AND DEVICE FOR EXECUTING THE SET |
| US4097237A (en) * | 1977-03-04 | 1978-06-27 | Technicon Instruments Corporation | Determination of cells in blood |
| GB1603643A (en) * | 1978-03-06 | 1981-11-25 | Coulter Electronics | Detection of blood disorders |
| US4243883A (en) * | 1979-01-19 | 1981-01-06 | Midwest Cardiovascular Institute Foundation | Blood hematocrit monitoring system |
| US4798803A (en) * | 1985-07-10 | 1989-01-17 | The Dow Chemical Company | Method for titration flow injection analysis |
| US5139956A (en) * | 1986-09-02 | 1992-08-18 | Fiatron-Eppendorf, Inc. | Method and system for determining peroxide content |
| EP2690446B1 (en) * | 2012-07-26 | 2016-12-07 | Mettler-Toledo GmbH | Sample divider |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3076600A (en) * | 1954-09-03 | 1963-02-05 | Jarrell Ash Company | Apparatus for counting discrete microscopic particles |
| BE627401A (en) * | 1962-01-23 |
-
1966
- 1966-07-11 US US564291A patent/US3427135A/en not_active Expired - Lifetime
-
1967
- 1967-06-22 GB GB28851/67A patent/GB1192192A/en not_active Expired
- 1967-06-28 FR FR112178A patent/FR1529316A/en not_active Expired
- 1967-07-07 SE SE10394/67A patent/SE340190B/xx unknown
- 1967-07-08 DE DE1673146A patent/DE1673146C3/en not_active Expired
- 1967-07-10 BE BE701133D patent/BE701133A/xx unknown
- 1967-07-10 JP JP42044098A patent/JPS512839B1/ja active Pending
- 1967-07-10 CH CH979467A patent/CH475558A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH475558A (en) | 1969-07-15 |
| JPS512839B1 (en) | 1976-01-29 |
| BE701133A (en) | 1968-01-10 |
| US3427135A (en) | 1969-02-11 |
| DE1673146A1 (en) | 1972-02-24 |
| DE1673146C3 (en) | 1975-02-27 |
| FR1529316A (en) | 1968-06-14 |
| SE340190B (en) | 1971-11-08 |
| DE1673146B2 (en) | 1974-07-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |