GB1190546A - Process for producing L-Threonine and L-Valine - Google Patents

Process for producing L-Threonine and L-Valine

Info

Publication number
GB1190546A
GB1190546A GB876869A GB876869A GB1190546A GB 1190546 A GB1190546 A GB 1190546A GB 876869 A GB876869 A GB 876869A GB 876869 A GB876869 A GB 876869A GB 1190546 A GB1190546 A GB 1190546A
Authority
GB
United Kingdom
Prior art keywords
growth
hydrocarbon
thiamine
atcc
valine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB876869A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of GB1190546A publication Critical patent/GB1190546A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

1,190,546. L-Threonine and L-valine by fermentation. KYOWA HAKKO KOGYO CO. Ltd. 18 Feb., 1969 [9 March, 1968], No. 8768/69. Heading C2C. L-Threonine and L-valine are produced by culturing a hydrocarbon-utilizing micro-organism, which requires thiamine and also isoleucine, α-ketobutyric acid, or α-aminobutyric acid for growth, under aerobic conditions in an aqueous nutrient medium containing thiamine, the growth requisite and a hydrocarbon or a mixture of hydrocarbons as the main source of carbon. Specified micro-organisms are Arthrobacter paraffineus ATCC 21220, Corynebacterium hydrocarboclastus ATCC 21221, and Brevibacterium ketoglutamicum ATCC 21222, and the hydrocarbon source is preferably one or more straight or branched chain alkanes of from 10 to 20 carbon atoms, e.g. a C 11 -C 18 nparaffin mixture or kerosene. The growth requisites are preferably present in an amount of 5-50 mg./l. medium, the concentration of thiamine is between 1 and 5 mg./l, and the pH is approximately 7. The medium may also contain citric, succinic, malic, fumaric or acetic acids, their sodium salts or L-homoserine, resulting in higher yields. Small amounts of other amino acids occur as by-products of the process. Specifications 1,117,154 and 1,122,508 are referred to.
GB876869A 1968-03-09 1969-02-18 Process for producing L-Threonine and L-Valine Expired GB1190546A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1494068A JPS5146836B1 (en) 1968-03-09 1968-03-09

Publications (1)

Publication Number Publication Date
GB1190546A true GB1190546A (en) 1970-05-06

Family

ID=11874941

Family Applications (1)

Application Number Title Priority Date Filing Date
GB876869A Expired GB1190546A (en) 1968-03-09 1969-02-18 Process for producing L-Threonine and L-Valine

Country Status (4)

Country Link
JP (1) JPS5146836B1 (en)
DE (1) DE1912799A1 (en)
FR (1) FR2003584A1 (en)
GB (1) GB1190546A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2411209A1 (en) * 1973-03-09 1974-09-12 Ajinomoto Kk METHOD FOR FERMENTATIONAL PRODUCTION OF L-VALIN
GB2147579A (en) * 1983-08-05 1985-05-15 Grace W R & Co Production of L-amino acids from alpha-keto acids by fermentation
GB2147580A (en) * 1983-08-05 1985-05-15 Grace W R & Co Improved process for producing L-amino acids from alpha-keto acids by fed-batch fermentation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2411209A1 (en) * 1973-03-09 1974-09-12 Ajinomoto Kk METHOD FOR FERMENTATIONAL PRODUCTION OF L-VALIN
GB2147579A (en) * 1983-08-05 1985-05-15 Grace W R & Co Production of L-amino acids from alpha-keto acids by fermentation
GB2147580A (en) * 1983-08-05 1985-05-15 Grace W R & Co Improved process for producing L-amino acids from alpha-keto acids by fed-batch fermentation

Also Published As

Publication number Publication date
JPS5146836B1 (en) 1976-12-11
DE1912799A1 (en) 1970-09-24
FR2003584A1 (en) 1969-11-07

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees