GB1183060A - A Substituted 1,4-3H-Benzodiazepin-2(1H)-One-Chloral Hydrate Reaction Product - Google Patents

A Substituted 1,4-3H-Benzodiazepin-2(1H)-One-Chloral Hydrate Reaction Product

Info

Publication number
GB1183060A
GB1183060A GB1099268A GB1099268A GB1183060A GB 1183060 A GB1183060 A GB 1183060A GB 1099268 A GB1099268 A GB 1099268A GB 1099268 A GB1099268 A GB 1099268A GB 1183060 A GB1183060 A GB 1183060A
Authority
GB
United Kingdom
Prior art keywords
benzodiazepin
chloral hydrate
substituted
march
reaction product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1099268A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Delmar Chemicals Inc
Original Assignee
Delmar Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delmar Chemicals Inc filed Critical Delmar Chemicals Inc
Publication of GB1183060A publication Critical patent/GB1183060A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,183,060. 1,4 - 3H - Benzodiazepin - 2(1H)- one-chloralhydrate derivative. DELMAR CHEMICALS Ltd. 6 March, 1968 [6 March, 1967], No. 10992/68. Heading C2C. A novel chemical substance having a molecular formula of C 18 H 16 Cl 4 N 2 O 3 , further characterized by a melting point of 110‹ to 118‹C. and by infra-red absorption bands at about 3430 cm.<SP>-1</SP> and 1670 cm.<SP>-1</SP>, results from reaction between 7 - chloro - 1 - methyl - 5 - phenyl - 1,4- 3H-benzodiazepin-2(1H)-one and chloral hydrate, which may be carried out at a temperature above room temperature in the absence of a solvent, or in a medium of a substantially non- polar solvent at or above room temperature. Pharmaceutical compositions having tranquillizing, anti-convulsive and muscle relaxant properties and containing the compound defined above are administered orally in association with the usual pharmaceutical carriers.
GB1099268A 1967-03-06 1968-03-06 A Substituted 1,4-3H-Benzodiazepin-2(1H)-One-Chloral Hydrate Reaction Product Expired GB1183060A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62079967A 1967-03-06 1967-03-06

Publications (1)

Publication Number Publication Date
GB1183060A true GB1183060A (en) 1970-03-04

Family

ID=24487444

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1099268A Expired GB1183060A (en) 1967-03-06 1968-03-06 A Substituted 1,4-3H-Benzodiazepin-2(1H)-One-Chloral Hydrate Reaction Product

Country Status (13)

Country Link
AT (1) AT286991B (en)
BE (1) BE711676A (en)
CH (1) CH505117A (en)
DK (1) DK121234B (en)
FI (1) FI48351C (en)
FR (2) FR1583753A (en)
GB (1) GB1183060A (en)
IE (1) IE31974B1 (en)
IL (1) IL29580A (en)
LU (1) LU55619A1 (en)
NL (2) NL6803061A (en)
NO (1) NO119841B (en)
SE (1) SE342629B (en)

Also Published As

Publication number Publication date
CH505117A (en) 1971-03-31
IE31974B1 (en) 1973-03-07
FI48351C (en) 1974-09-10
IL29580A (en) 1971-12-29
FR7640M (en) 1970-02-02
FI48351B (en) 1974-05-31
NO119841B (en) 1970-07-13
IE31974L (en) 1968-09-06
FR1583753A (en) 1969-12-05
NL6803061A (en) 1968-09-09
DE1670593B2 (en) 1975-12-04
DK121234B (en) 1971-09-27
BE711676A (en) 1968-09-05
AT286991B (en) 1971-01-11
SE342629B (en) 1972-02-14
NL138681C (en)
DE1670593A1 (en) 1972-01-27
LU55619A1 (en) 1969-10-02

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees