IE31974B1 - A substituted 1,4-3h-benzodiazepin-2(1h)-one-chloral hydrate reaction product - Google Patents

A substituted 1,4-3h-benzodiazepin-2(1h)-one-chloral hydrate reaction product

Info

Publication number
IE31974B1
IE31974B1 IE25668A IE25668A IE31974B1 IE 31974 B1 IE31974 B1 IE 31974B1 IE 25668 A IE25668 A IE 25668A IE 25668 A IE25668 A IE 25668A IE 31974 B1 IE31974 B1 IE 31974B1
Authority
IE
Ireland
Prior art keywords
benzodiazepin
chloral hydrate
substituted
reaction product
hydrate reaction
Prior art date
Application number
IE25668A
Other versions
IE31974L (en
Original Assignee
Delmar Chem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delmar Chem filed Critical Delmar Chem
Publication of IE31974L publication Critical patent/IE31974L/en
Publication of IE31974B1 publication Critical patent/IE31974B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

7-Chloro-1-methyl-5-phenyl-1,4-3H-benzodiazepin-2(1H)-one chloral hydrate (I) with the following properties.: m.p. 110 deg.C I.R. absorption bands at 1670 and 3430 cm-1. Tranquilliser, anticonvulsant, muscle relaxant. Reaction of equimolar amts. of 7-chloro-1-methyl-5-phenyl-1,4-3H-benzodiazepin-2(1H)-one (II) and chloral hydrate (III), either with heating or in a solvent. [CH505117A]
IE25668A 1967-03-06 1968-03-05 A substituted 1,4-3h-benzodiazepin-2(1h)-one-chloral hydrate reaction product IE31974B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62079967A 1967-03-06 1967-03-06

Publications (2)

Publication Number Publication Date
IE31974L IE31974L (en) 1968-09-06
IE31974B1 true IE31974B1 (en) 1973-03-07

Family

ID=24487444

Family Applications (1)

Application Number Title Priority Date Filing Date
IE25668A IE31974B1 (en) 1967-03-06 1968-03-05 A substituted 1,4-3h-benzodiazepin-2(1h)-one-chloral hydrate reaction product

Country Status (13)

Country Link
AT (1) AT286991B (en)
BE (1) BE711676A (en)
CH (1) CH505117A (en)
DK (1) DK121234B (en)
FI (1) FI48351C (en)
FR (2) FR1583753A (en)
GB (1) GB1183060A (en)
IE (1) IE31974B1 (en)
IL (1) IL29580A (en)
LU (1) LU55619A1 (en)
NL (2) NL6803061A (en)
NO (1) NO119841B (en)
SE (1) SE342629B (en)

Also Published As

Publication number Publication date
CH505117A (en) 1971-03-31
AT286991B (en) 1971-01-11
NL138681C (en)
FR7640M (en) 1970-02-02
BE711676A (en) 1968-09-05
FI48351C (en) 1974-09-10
DE1670593A1 (en) 1972-01-27
NL6803061A (en) 1968-09-09
NO119841B (en) 1970-07-13
SE342629B (en) 1972-02-14
FR1583753A (en) 1969-12-05
DK121234B (en) 1971-09-27
IL29580A (en) 1971-12-29
LU55619A1 (en) 1969-10-02
GB1183060A (en) 1970-03-04
DE1670593B2 (en) 1975-12-04
IE31974L (en) 1968-09-06
FI48351B (en) 1974-05-31

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