GB1180616A - Improvements in or relating to Hexahydroazepine Compounds and the Manufacture thereof - Google Patents

Improvements in or relating to Hexahydroazepine Compounds and the Manufacture thereof

Info

Publication number
GB1180616A
GB1180616A GB4488369A GB4488369A GB1180616A GB 1180616 A GB1180616 A GB 1180616A GB 4488369 A GB4488369 A GB 4488369A GB 4488369 A GB4488369 A GB 4488369A GB 1180616 A GB1180616 A GB 1180616A
Authority
GB
United Kingdom
Prior art keywords
azepin
benzoyl
benzoylhexahydro
phenylhydrazones
hexahydroazepine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4488369A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB1180616A publication Critical patent/GB1180616A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GB4488369A 1966-05-10 1967-04-17 Improvements in or relating to Hexahydroazepine Compounds and the Manufacture thereof Expired GB1180616A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54888066A 1966-05-10 1966-05-10

Publications (1)

Publication Number Publication Date
GB1180616A true GB1180616A (en) 1970-02-04

Family

ID=24190763

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1757867A Expired GB1180615A (en) 1966-05-10 1967-04-17 Novel Substituted Hexahydroazepino-(4,5-b) Indoles
GB4488369A Expired GB1180616A (en) 1966-05-10 1967-04-17 Improvements in or relating to Hexahydroazepine Compounds and the Manufacture thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB1757867A Expired GB1180615A (en) 1966-05-10 1967-04-17 Novel Substituted Hexahydroazepino-(4,5-b) Indoles

Country Status (9)

Country Link
BE (1) BE698268A (fr)
CH (1) CH506543A (fr)
DE (1) DE1695943A1 (fr)
ES (1) ES340258A1 (fr)
FR (1) FR6699M (fr)
GB (2) GB1180615A (fr)
GR (1) GR35044B (fr)
IL (2) IL36801A (fr)
NL (1) NL6706513A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7485634B2 (en) 2002-05-24 2009-02-03 Exelixis, Inc. Azepinoindole and pyridoindole derivatives as pharmaceutical agents
US7595311B2 (en) 2002-05-24 2009-09-29 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2029828B (en) * 1978-08-24 1983-04-27 Omnium Chimique Sa Vincadifformine derivatives
FR2663935A1 (fr) * 1990-06-27 1992-01-03 Adir Nouveaux 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles et 1,2,3,4-tetrahydrobethacarbolines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US7030109B2 (en) 1999-07-19 2006-04-18 Pharmacia & Upjohn Company 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
MY122278A (en) 1999-07-19 2006-04-29 Upjohn Co 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
WO2002004456A1 (fr) * 2000-07-06 2002-01-17 Pharmacia & Upjohn Company 2,3,7,8,9,10,11,12-octahydroazepino[4,5-b]pyrano[3,2-e]indoles substitutes
AR034264A1 (es) * 2000-09-20 2004-02-18 Upjohn Co Derivados azepino(4,5-b)indol sustituidos y composiciones farmaceuticas
AU2004259009A1 (en) 2003-07-23 2005-02-03 Exelixis, Inc. Azepine derivatives as pharmaceutical agents
US20230257385A1 (en) 2021-11-17 2023-08-17 Terran Biosciences Inc. Salt and solid forms of tabernanthalog

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7485634B2 (en) 2002-05-24 2009-02-03 Exelixis, Inc. Azepinoindole and pyridoindole derivatives as pharmaceutical agents
US7595311B2 (en) 2002-05-24 2009-09-29 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents

Also Published As

Publication number Publication date
GB1180615A (en) 1970-02-04
DE1695943A1 (de) 1971-05-13
ES340258A1 (es) 1968-06-01
NL6706513A (fr) 1967-11-13
IL36801A (en) 1971-11-29
CH506543A (de) 1971-04-30
IL27776A (en) 1971-11-29
BE698268A (fr) 1967-11-10
GR35044B (el) 1968-07-31
FR6699M (fr) 1969-02-10

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