GB1178786A - New 1,3,4-oxathiazole derivatives, their preparation, and their Pharmaceutical use - Google Patents
New 1,3,4-oxathiazole derivatives, their preparation, and their Pharmaceutical useInfo
- Publication number
- GB1178786A GB1178786A GB32264/68A GB3226468A GB1178786A GB 1178786 A GB1178786 A GB 1178786A GB 32264/68 A GB32264/68 A GB 32264/68A GB 3226468 A GB3226468 A GB 3226468A GB 1178786 A GB1178786 A GB 1178786A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- general formula
- carbon atoms
- total
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YYUIROVDIXDEKU-UHFFFAOYSA-N 1,3,4-oxathiazole Chemical class C1OC=NS1 YYUIROVDIXDEKU-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 238000006243 chemical reaction Methods 0.000 abstract 5
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- NHNUIHVGYRHTTC-UHFFFAOYSA-N N-benzyl-3,3-dioxo-1,3,4-oxathiazolidin-5-imine Chemical class C(C1=CC=CC=C1)NC1=NS(CO1)(=O)=O NHNUIHVGYRHTTC-UHFFFAOYSA-N 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 150000007530 organic bases Chemical group 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 2
- 229910001860 alkaline earth metal hydroxide Inorganic materials 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- WGQKYBSKWIADBV-UHFFFAOYSA-N benzylamine Chemical compound NCC1=CC=CC=C1 WGQKYBSKWIADBV-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 239000003495 polar organic solvent Substances 0.000 abstract 2
- 238000007363 ring formation reaction Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004434 sulfur atom Chemical group 0.000 abstract 2
- JOZKKHBHVQMRHT-UHFFFAOYSA-N 1-chloro-3-(isocyanatomethyl)benzene Chemical compound ClC1=CC=CC(CN=C=O)=C1 JOZKKHBHVQMRHT-UHFFFAOYSA-N 0.000 abstract 1
- UHSBFNPAYOCVSO-UHFFFAOYSA-N 1-chloroethanesulfonamide Chemical compound CC(Cl)S(N)(=O)=O UHSBFNPAYOCVSO-UHFFFAOYSA-N 0.000 abstract 1
- DJTHQXQNLGUJOP-UHFFFAOYSA-N 3,3-dioxo-1,3,4-oxathiazol-5-amine Chemical compound NC1=NS(=O)(=O)CO1 DJTHQXQNLGUJOP-UHFFFAOYSA-N 0.000 abstract 1
- KNIUHBNRWZGIQQ-UHFFFAOYSA-N 7-diethoxyphosphinothioyloxy-4-methylchromen-2-one Chemical compound CC1=CC(=O)OC2=CC(OP(=S)(OCC)OCC)=CC=C21 KNIUHBNRWZGIQQ-UHFFFAOYSA-N 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- -1 benzyl halide Chemical class 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- AVXHCUKQISJQBN-UHFFFAOYSA-N chloromethanesulfonamide Chemical compound NS(=O)(=O)CCl AVXHCUKQISJQBN-UHFFFAOYSA-N 0.000 abstract 1
- LBHPTWRXQDIFPC-UHFFFAOYSA-N chloromethylsulfonyl(phenyl)carbamic acid Chemical compound C1=CC=C(C=C1)N(C(=O)O)S(=O)(=O)CCl LBHPTWRXQDIFPC-UHFFFAOYSA-N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 229910052740 iodine Chemical group 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- AHWALFGBDFAJAI-UHFFFAOYSA-N phenyl carbonochloridate Chemical compound ClC(=O)OC1=CC=CC=C1 AHWALFGBDFAJAI-UHFFFAOYSA-N 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
- C07D291/02—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms not condensed with other rings
- C07D291/04—Five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0052869 | 1967-07-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1178786A true GB1178786A (en) | 1970-01-21 |
Family
ID=7105803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB32264/68A Expired GB1178786A (en) | 1967-07-06 | 1968-07-05 | New 1,3,4-oxathiazole derivatives, their preparation, and their Pharmaceutical use |
Country Status (6)
| Country | Link |
|---|---|
| AT (1) | AT277238B (enExample) |
| BE (1) | BE717708A (enExample) |
| ES (1) | ES355824A1 (enExample) |
| GB (1) | GB1178786A (enExample) |
| IL (1) | IL30280A0 (enExample) |
| NL (1) | NL6809567A (enExample) |
-
1968
- 1968-07-01 IL IL30280A patent/IL30280A0/xx unknown
- 1968-07-04 AT AT641268A patent/AT277238B/de not_active IP Right Cessation
- 1968-07-05 BE BE717708D patent/BE717708A/xx unknown
- 1968-07-05 GB GB32264/68A patent/GB1178786A/en not_active Expired
- 1968-07-05 NL NL6809567A patent/NL6809567A/xx unknown
- 1968-07-06 ES ES355824A patent/ES355824A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES355824A1 (es) | 1970-01-01 |
| BE717708A (enExample) | 1969-01-06 |
| AT277238B (de) | 1969-12-10 |
| IL30280A0 (en) | 1968-09-26 |
| NL6809567A (enExample) | 1969-01-08 |
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