GB1173942A - New 2,3-Dihydro-1,4-Benzoxazines - Google Patents

New 2,3-Dihydro-1,4-Benzoxazines

Info

Publication number
GB1173942A
GB1173942A GB25999/67A GB2599967A GB1173942A GB 1173942 A GB1173942 A GB 1173942A GB 25999/67 A GB25999/67 A GB 25999/67A GB 2599967 A GB2599967 A GB 2599967A GB 1173942 A GB1173942 A GB 1173942A
Authority
GB
United Kingdom
Prior art keywords
dihydro
benzoxazine
oxo
alkyl
carbethoxymethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB25999/67A
Other languages
English (en)
Inventor
Marcel Pesson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Roger Bellon SA
Original Assignee
Laboratoire Roger Bellon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Roger Bellon SA filed Critical Laboratoire Roger Bellon SA
Priority to GB25999/67A priority Critical patent/GB1173942A/en
Priority to FR153267A priority patent/FR7697M/fr
Priority to FR1593525D priority patent/FR1593525A/fr
Priority to BE715883D priority patent/BE715883A/xx
Priority to DK260468AA priority patent/DK125711B/da
Priority to US734223A priority patent/US3681330A/en
Priority to SE07514/68A priority patent/SE328889B/xx
Priority to CH828268A priority patent/CH499534A/fr
Priority to NL6807873.A priority patent/NL158796B/xx
Priority to DE1770565A priority patent/DE1770565C3/de
Publication of GB1173942A publication Critical patent/GB1173942A/en
Priority to US75281A priority patent/US3705894A/en
Priority to US269340A priority patent/US3879522A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB25999/67A 1967-06-06 1967-06-06 New 2,3-Dihydro-1,4-Benzoxazines Expired GB1173942A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
GB25999/67A GB1173942A (en) 1967-06-06 1967-06-06 New 2,3-Dihydro-1,4-Benzoxazines
FR153267A FR7697M (en:Method) 1967-06-06 1968-05-29
FR1593525D FR1593525A (en:Method) 1967-06-06 1968-05-29
BE715883D BE715883A (en:Method) 1967-06-06 1968-05-30
US734223A US3681330A (en) 1967-06-06 1968-06-04 2,3-dihydro-1,4-benzoxazines
DK260468AA DK125711B (da) 1967-06-06 1968-06-04 Analogifremgangsmåde til fremstilling af 3-oxo-2,3-dihydro-1,4-benzoxazinderivater.
SE07514/68A SE328889B (en:Method) 1967-06-06 1968-06-05
CH828268A CH499534A (fr) 1967-06-06 1968-06-05 Procédé de préparation d'oxo-3a-carboxamidoalcoyl-4 dihydro-2,3 benzoxazines-1,4
NL6807873.A NL158796B (nl) 1967-06-06 1968-06-05 Werkwijze voor het bereiden van 4-gesubstitueerde-3-oxo-2,3-dihydro-benzo-1,4 oxazinen, werkwijze voor het bereiden van geneesmiddelen met deze verbindingen als actieve stoffen, alsmede aldus verkregen gevormde geneesmiddelen.
DE1770565A DE1770565C3 (de) 1967-06-06 1968-06-05 S-Oxo^-carboxamidomethyl^dihydro-l,4-benzoxazin und pharmazeutische Mittel, enthaltend diese Verbindung
US75281A US3705894A (en) 1967-06-06 1970-09-24 Mycophenolic acid derivatives
US269340A US3879522A (en) 1967-06-06 1972-07-06 New 2,3-dihydro-1,4-benzoxazines in compositions effecting the central nervous system

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB25999/67A GB1173942A (en) 1967-06-06 1967-06-06 New 2,3-Dihydro-1,4-Benzoxazines
US73422368A 1968-06-04 1968-06-04
CH828268A CH499534A (fr) 1967-06-06 1968-06-05 Procédé de préparation d'oxo-3a-carboxamidoalcoyl-4 dihydro-2,3 benzoxazines-1,4
US7528170A 1970-09-24 1970-09-24
US269340A US3879522A (en) 1967-06-06 1972-07-06 New 2,3-dihydro-1,4-benzoxazines in compositions effecting the central nervous system

Publications (1)

Publication Number Publication Date
GB1173942A true GB1173942A (en) 1969-12-10

Family

ID=27509330

Family Applications (1)

Application Number Title Priority Date Filing Date
GB25999/67A Expired GB1173942A (en) 1967-06-06 1967-06-06 New 2,3-Dihydro-1,4-Benzoxazines

Country Status (7)

Country Link
US (3) US3681330A (en:Method)
BE (1) BE715883A (en:Method)
CH (1) CH499534A (en:Method)
DE (1) DE1770565C3 (en:Method)
FR (2) FR1593525A (en:Method)
GB (1) GB1173942A (en:Method)
NL (1) NL158796B (en:Method)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2564463A1 (fr) * 1984-05-18 1985-11-22 Carpibem Nouveaux derives heterocycliques, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase
EP0162776A3 (en) * 1984-05-18 1987-05-06 Carpibem, Societe Anonyme Dite : Heterocyclic derivatives, process for their preparation and medicaments useful as aldose reductase inhibitors containing them
US4771050A (en) * 1986-04-17 1988-09-13 Takeda Chemical Industries, Ltd. Thiolactam-n-acetic acid derivatives
EP0290863A3 (en) * 1987-05-09 1989-03-15 Nihon Tokushu Noyaku Seizo K.K. Benzoxazine derivative, process and intermediates for its preparation and its use as herbicide
EP0441539A3 (en) * 1990-02-08 1992-04-15 Tanabe Seiyaku Co., Ltd. Thiazine (or oxazine) derivatives and preparation thereof
US5496815A (en) * 1990-02-08 1996-03-05 Tanabe Seiyaku Co., Ltd. Thiazine (or oxazine) derivatives and preparation thereof
AU774186B2 (en) * 1999-12-06 2004-06-17 Les Laboratoires Servier New substituted (dihydro)benzoxazine and (dihydro) benzothiazine compounds, a process for their preparation and pharmaceutical compositions containing them
US9101634B2 (en) 2010-05-20 2015-08-11 Shandong University Application of 2, 3-dihydro-3-hydroxymethyl-6-amino-[1,4]-benzoxazine in preparation of drugs inducing embryonic stem cells to differentiate to vascular endothelial cells
GB2568549A (en) * 2017-11-21 2019-05-22 Univ Leicester New compounds and uses

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755327A (en) * 1967-06-05 1973-08-28 Fujisawa Pharmaceutical Co 1(homo)piperazinyl carbonyl alkyl 2(3h) benzimidozalinones and 2(3h) benzothiozolinone
GB1285711A (en) * 1968-11-08 1972-08-16 Bellon Labor Sa Roger New benzoxazine derivatives
JPS5542995B2 (en:Method) * 1972-02-24 1980-11-04
US3868454A (en) * 1972-08-14 1975-02-25 Lilly Co Eli Psoriasis treatment with mycophenolic acid derivatives
US4333943A (en) * 1980-04-24 1982-06-08 Miles Laboratories, Inc. Ethyl 3-(3-indolyl)-3-(5-tetrazolyl) propionate compounds used as anti-hypertensive agents
US4686234A (en) * 1985-11-27 1987-08-11 Syntex (U.S.A) Inc. Mycophenolic acid derivatives in the treatment of inflammatory diseases, in particular rheumatoid arthritis
US4725622A (en) * 1986-01-23 1988-02-16 Syntex (U.S.A.) Inc. Mycophenolic acid derivatives in the treatment of rheumatoid arthritis
US4753935A (en) * 1987-01-30 1988-06-28 Syntex (U.S.A.) Inc. Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions
US5177072A (en) * 1987-01-30 1993-01-05 Syntex (U.S.A.) Inc. Treatment of autoimmune inflammatory, and psoriatic diseases with heterocyclic aminoalkyl esters of mycophenolic acid and derivatives
TW224941B (en:Method) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd
US5420126A (en) * 1989-11-08 1995-05-30 Yamanouchi Pharmaceutical Co., Ltd. 3,4-dihydro-2H-1,4-benzoxazine derivatives and pharmaceutical compositions containing the same
ID18663A (id) * 1996-04-12 1998-04-30 Novartis Ag Komposisi farmasi berlapis enterik
US6471980B2 (en) 2000-12-22 2002-10-29 Avantec Vascular Corporation Intravascular delivery of mycophenolic acid
US7077859B2 (en) 2000-12-22 2006-07-18 Avantec Vascular Corporation Apparatus and methods for variably controlled substance delivery from implanted prostheses
US7083642B2 (en) 2000-12-22 2006-08-01 Avantec Vascular Corporation Delivery of therapeutic capable agents
EP1667987B1 (en) * 2003-09-11 2008-07-23 Sandoz AG Process for the production of mycophenolate mofetil
CA2935944A1 (en) * 2014-01-09 2015-07-16 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Substituted benzoxazine and related compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2850495A (en) * 1957-11-12 1958-09-02 Dow Chemical Co 3, 4-dihydro-2-oxo-2h-1, 4-benzoxazine-4-acetic acids
FR1307154A (fr) * 1960-12-01 1962-10-19 Geigy Ag J R Antiseptique à base de dérivés de la benzoxazine

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2564463A1 (fr) * 1984-05-18 1985-11-22 Carpibem Nouveaux derives heterocycliques, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase
EP0162776A3 (en) * 1984-05-18 1987-05-06 Carpibem, Societe Anonyme Dite : Heterocyclic derivatives, process for their preparation and medicaments useful as aldose reductase inhibitors containing them
US4755509A (en) * 1984-05-18 1988-07-05 Carbipem Heterocyclic aldose reductase inhibitors and methods of using them
US4771050A (en) * 1986-04-17 1988-09-13 Takeda Chemical Industries, Ltd. Thiolactam-n-acetic acid derivatives
EP0290863A3 (en) * 1987-05-09 1989-03-15 Nihon Tokushu Noyaku Seizo K.K. Benzoxazine derivative, process and intermediates for its preparation and its use as herbicide
EP0441539A3 (en) * 1990-02-08 1992-04-15 Tanabe Seiyaku Co., Ltd. Thiazine (or oxazine) derivatives and preparation thereof
US5246929A (en) * 1990-02-08 1993-09-21 Tanabe Seiyaku Co., Ltd. Naphtho thiazine (or oxaline) derivatives and preparations thereof
US5281592A (en) * 1990-02-08 1994-01-25 Tanabe Seiyaku Co., Ltd. Thiazine derivatives and preparation thereof
US5496815A (en) * 1990-02-08 1996-03-05 Tanabe Seiyaku Co., Ltd. Thiazine (or oxazine) derivatives and preparation thereof
AU774186B2 (en) * 1999-12-06 2004-06-17 Les Laboratoires Servier New substituted (dihydro)benzoxazine and (dihydro) benzothiazine compounds, a process for their preparation and pharmaceutical compositions containing them
US9101634B2 (en) 2010-05-20 2015-08-11 Shandong University Application of 2, 3-dihydro-3-hydroxymethyl-6-amino-[1,4]-benzoxazine in preparation of drugs inducing embryonic stem cells to differentiate to vascular endothelial cells
GB2568549A (en) * 2017-11-21 2019-05-22 Univ Leicester New compounds and uses
WO2019102186A1 (en) * 2017-11-21 2019-05-31 University Of Leicester Kynurenine 3-monooxygenase (kmo) inhibitors, and uses and compositions thereof

Also Published As

Publication number Publication date
NL158796B (nl) 1978-12-15
DE1770565A1 (de) 1972-03-09
NL6807873A (en:Method) 1968-12-09
CH499534A (fr) 1970-11-30
DE1770565C3 (de) 1979-10-18
FR7697M (en:Method) 1970-02-23
US3681330A (en) 1972-08-01
BE715883A (en:Method) 1968-10-16
DE1770565B2 (de) 1979-02-22
US3705894A (en) 1972-12-12
FR1593525A (en:Method) 1970-06-01
US3879522A (en) 1975-04-22

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
435 Patent endorsed 'licences of right' on the date specified (sect. 35/1949)
PCNP Patent ceased through non-payment of renewal fee