GB1173342A - Process for the preparation of Pyrazinoylguanidines and Pyrazinamido Guanidines and Intermediates produced in the process - Google Patents

Process for the preparation of Pyrazinoylguanidines and Pyrazinamido Guanidines and Intermediates produced in the process

Info

Publication number
GB1173342A
GB1173342A GB26215/67A GB2621567A GB1173342A GB 1173342 A GB1173342 A GB 1173342A GB 26215/67 A GB26215/67 A GB 26215/67A GB 2621567 A GB2621567 A GB 2621567A GB 1173342 A GB1173342 A GB 1173342A
Authority
GB
United Kingdom
Prior art keywords
general formula
alkyl
alkyl group
diamino
halo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB26215/67A
Other languages
English (en)
Inventor
Peter Immanuel Pollak
Roger James Tull
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1173342A publication Critical patent/GB1173342A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Selective Calling Equipment (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB26215/67A 1966-08-25 1967-06-07 Process for the preparation of Pyrazinoylguanidines and Pyrazinamido Guanidines and Intermediates produced in the process Expired GB1173342A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US574904A US3328404A (en) 1966-08-25 1966-08-25 Derivatives of pyrazine

Publications (1)

Publication Number Publication Date
GB1173342A true GB1173342A (en) 1969-12-10

Family

ID=24298126

Family Applications (1)

Application Number Title Priority Date Filing Date
GB26215/67A Expired GB1173342A (en) 1966-08-25 1967-06-07 Process for the preparation of Pyrazinoylguanidines and Pyrazinamido Guanidines and Intermediates produced in the process

Country Status (7)

Country Link
US (1) US3328404A (enExample)
CH (1) CH493535A (enExample)
ES (1) ES341318A1 (enExample)
GB (1) GB1173342A (enExample)
NL (1) NL6707562A (enExample)
NO (1) NO118108B (enExample)
SE (1) SE324368B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208413A (en) * 1977-03-04 1980-06-17 Merck & Co., Inc. N-Pyrazinecarbonyl-N'-alkoxycarbonyl and N',N"-bis(alkoxycarbonyl)guanidines and processes for preparing same
US4246406A (en) * 1979-03-27 1981-01-20 Merck & Co., Inc. Heterocyclic substituted pyrazinoylguanidines
US4604394A (en) * 1984-10-01 1986-08-05 Merck & Co., Inc. Antiarrhythmic compositions and method
PL2444120T3 (pl) 2007-12-10 2018-02-28 Novartis Ag Spirocyklicze analogi amiloridu jako blokery ENac

Also Published As

Publication number Publication date
SE324368B (enExample) 1970-06-01
US3328404A (en) 1967-06-27
ES341318A1 (es) 1968-10-16
CH493535A (de) 1970-07-15
NL6707562A (enExample) 1968-02-26
NO118108B (enExample) 1969-11-10

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees