GB1167386A - Novel Derivatives of Cyclohexane - Google Patents
Novel Derivatives of CyclohexaneInfo
- Publication number
- GB1167386A GB1167386A GB1921067A GB1921067A GB1167386A GB 1167386 A GB1167386 A GB 1167386A GB 1921067 A GB1921067 A GB 1921067A GB 1921067 A GB1921067 A GB 1921067A GB 1167386 A GB1167386 A GB 1167386A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reacting
- ester
- phenyl
- ethyl
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000113 cyclohexyl group Chemical class [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000007818 Grignard reagent Substances 0.000 abstract 2
- 150000004795 grignard reagents Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- -1 piperidino - Chemical class 0.000 abstract 2
- SIGZQOSGZJNAKB-UHFFFAOYSA-N 2-(hydroxymethyl)cyclohexan-1-one Chemical compound OCC1CCCCC1=O SIGZQOSGZJNAKB-UHFFFAOYSA-N 0.000 abstract 1
- VCZPUGSOJXZKIP-UHFFFAOYSA-N 2-hydroxy-2-phenylcyclohexanecarboxylic acid Chemical compound OC(=O)C1CCCCC1(O)C1=CC=CC=C1 VCZPUGSOJXZKIP-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- UYACNTWHONQGNB-UHFFFAOYSA-N acetic acid;cyclohexanone Chemical compound CC(O)=O.O=C1CCCCC1 UYACNTWHONQGNB-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000003973 alkyl amines Chemical class 0.000 abstract 1
- 230000001663 anti-spastic effect Effects 0.000 abstract 1
- 239000000731 choleretic agent Substances 0.000 abstract 1
- 230000001989 choleretic effect Effects 0.000 abstract 1
- 150000001934 cyclohexanes Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000004494 ethyl ester group Chemical group 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/02—Saturated compounds containing hydroxy or O-metal groups
- C07C62/04—Saturated compounds containing hydroxy or O-metal groups with a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT991366 | 1966-04-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1167386A true GB1167386A (en) | 1969-10-15 |
Family
ID=11133413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1921067A Expired GB1167386A (en) | 1966-04-29 | 1967-04-26 | Novel Derivatives of Cyclohexane |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS504652B1 (enrdf_load_stackoverflow) |
| CH (1) | CH522592A (enrdf_load_stackoverflow) |
| FR (1) | FR7240M (enrdf_load_stackoverflow) |
| GB (1) | GB1167386A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2947160A1 (de) * | 1978-11-24 | 1980-06-12 | Guidotti & C Spa Labor | Verfahren zur herstellung basischer ester von substituierten hydroxycyclohexancarbonsaeuren |
| CN106631760A (zh) * | 2015-10-29 | 2017-05-10 | 上海医药工业研究院 | 顺-1-羟基-[1,1’-双(环己烷)]-2-羧酸的制备工艺 |
-
1967
- 1967-04-20 CH CH562367A patent/CH522592A/de not_active IP Right Cessation
- 1967-04-26 GB GB1921067A patent/GB1167386A/en not_active Expired
- 1967-04-27 FR FR42009713A patent/FR7240M/fr not_active Expired
- 1967-04-28 JP JP42027231A patent/JPS504652B1/ja active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2947160A1 (de) * | 1978-11-24 | 1980-06-12 | Guidotti & C Spa Labor | Verfahren zur herstellung basischer ester von substituierten hydroxycyclohexancarbonsaeuren |
| FR2442225A1 (fr) * | 1978-11-24 | 1980-06-20 | Guidotti & C Spa Labor | Procede de preparation d'esters basiques d'acides hydroxycyclohexane-carboxyliques substitues |
| CN106631760A (zh) * | 2015-10-29 | 2017-05-10 | 上海医药工业研究院 | 顺-1-羟基-[1,1’-双(环己烷)]-2-羧酸的制备工艺 |
| CN106631760B (zh) * | 2015-10-29 | 2019-05-28 | 上海医药工业研究院 | 顺-1-羟基-[1,1’-双(环己烷)]-2-羧酸的制备工艺 |
Also Published As
| Publication number | Publication date |
|---|---|
| CH522592A (de) | 1972-06-30 |
| JPS504652B1 (enrdf_load_stackoverflow) | 1975-02-22 |
| FR7240M (enrdf_load_stackoverflow) | 1969-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE | Patent expired |