GB1166595A - Improvements in or relating to Piperazinyl Derivatives - Google Patents

Improvements in or relating to Piperazinyl Derivatives

Info

Publication number
GB1166595A
GB1166595A GB850368A GB850368A GB1166595A GB 1166595 A GB1166595 A GB 1166595A GB 850368 A GB850368 A GB 850368A GB 850368 A GB850368 A GB 850368A GB 1166595 A GB1166595 A GB 1166595A
Authority
GB
United Kingdom
Prior art keywords
carbon atoms
atoms inclusive
aryl
halogen
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB850368A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of GB1166595A publication Critical patent/GB1166595A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB850368A 1967-03-22 1968-02-21 Improvements in or relating to Piperazinyl Derivatives Expired GB1166595A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB0091744 1967-03-22

Publications (1)

Publication Number Publication Date
GB1166595A true GB1166595A (en) 1969-10-08

Family

ID=6986011

Family Applications (1)

Application Number Title Priority Date Filing Date
GB850368A Expired GB1166595A (en) 1967-03-22 1968-02-21 Improvements in or relating to Piperazinyl Derivatives

Country Status (9)

Country Link
AT (1) AT278814B (enrdf_load_stackoverflow)
BE (1) BE710768A (enrdf_load_stackoverflow)
CH (1) CH507260A (enrdf_load_stackoverflow)
DE (1) DE1670200A1 (enrdf_load_stackoverflow)
ES (1) ES351896A1 (enrdf_load_stackoverflow)
FR (1) FR1577338A (enrdf_load_stackoverflow)
GB (1) GB1166595A (enrdf_load_stackoverflow)
NL (1) NL6802185A (enrdf_load_stackoverflow)
SE (1) SE343582B (enrdf_load_stackoverflow)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336382A (en) * 1979-09-06 1982-06-22 Hoffmann-La Roche Inc. 1,4-Disubstituted piperazine compounds
JPS59152379A (ja) * 1983-02-12 1984-08-31 レコルダチ　エス　エ−　ケミカル　アンド　フアマシユテイカル　カンパニ− Ｎ―ピペラジニルアルカノイルアニリド及びその製造法
WO1989006961A1 (en) * 1988-01-29 1989-08-10 Mitsubishi Kasei Corporation Antianxiety drug
US5219855A (en) * 1988-01-29 1993-06-15 Mitsubishi Kasei Corporation Anxiolytic drug
US5364849A (en) * 1989-04-22 1994-11-15 John Wyeth & Brother, Limited 1-[3 or 4-[1-[4-piperazinyl]]-2 arylpropionyl or butryl]-heterocyclic derivatives
US5382583A (en) * 1989-04-22 1995-01-17 John Wyeth & Brother, Limited Piperazine derivatives
US5403842A (en) * 1992-02-25 1995-04-04 Recordati S.A., Chemical And Pharmaceutical Company Benzopyran and benzothiopyran derivatives
US5453518A (en) * 1992-04-10 1995-09-26 Recordati S.A., Chemical And Pharmaceutical Company Flavone derivatives
US5474994A (en) * 1992-05-26 1995-12-12 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 -adrenergic and 5HT1A
US5605896A (en) * 1992-02-25 1997-02-25 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202978A (en) * 1978-02-08 1980-05-13 Hoffmann-La Roche Inc. (S)-1-[2-(4-(2-Hydroxy-s-(1-alkylaminopropoxy)phenylalkyl]-4-phenylpiperazines
US4766125A (en) * 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336382A (en) * 1979-09-06 1982-06-22 Hoffmann-La Roche Inc. 1,4-Disubstituted piperazine compounds
JPS59152379A (ja) * 1983-02-12 1984-08-31 レコルダチ　エス　エ−　ケミカル　アンド　フアマシユテイカル　カンパニ− Ｎ―ピペラジニルアルカノイルアニリド及びその製造法
EP0120558A1 (en) * 1983-02-12 1984-10-03 RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY Antihypertensive N-piperazinylalkanoylanilides
US4940711A (en) * 1983-02-12 1990-07-10 Recordati, S.A., Chemical And Pharmaceutical Company Antihypertensive N-piperazinylalkanoylanilides
WO1989006961A1 (en) * 1988-01-29 1989-08-10 Mitsubishi Kasei Corporation Antianxiety drug
US5219855A (en) * 1988-01-29 1993-06-15 Mitsubishi Kasei Corporation Anxiolytic drug
US5364849A (en) * 1989-04-22 1994-11-15 John Wyeth & Brother, Limited 1-[3 or 4-[1-[4-piperazinyl]]-2 arylpropionyl or butryl]-heterocyclic derivatives
US5382583A (en) * 1989-04-22 1995-01-17 John Wyeth & Brother, Limited Piperazine derivatives
US5403842A (en) * 1992-02-25 1995-04-04 Recordati S.A., Chemical And Pharmaceutical Company Benzopyran and benzothiopyran derivatives
US5605896A (en) * 1992-02-25 1997-02-25 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities
US5453518A (en) * 1992-04-10 1995-09-26 Recordati S.A., Chemical And Pharmaceutical Company Flavone derivatives
US5474994A (en) * 1992-05-26 1995-12-12 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 -adrenergic and 5HT1A

Also Published As

Publication number Publication date
SE343582B (enrdf_load_stackoverflow) 1972-03-13
DE1670200A1 (de) 1972-03-02
BE710768A (enrdf_load_stackoverflow) 1968-06-17
FR1577338A (enrdf_load_stackoverflow) 1969-08-08
CH507260A (de) 1971-05-15
NL6802185A (enrdf_load_stackoverflow) 1968-09-23
ES351896A1 (es) 1969-06-16
AT278814B (de) 1970-02-10

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees