GB1165104A - 0,5-Dimethyl Pseudotropine 3,4,5-Trimethoxybenzoic Acid Ester and its Derivatives - Google Patents

0,5-Dimethyl Pseudotropine 3,4,5-Trimethoxybenzoic Acid Ester and its Derivatives

Info

Publication number
GB1165104A
GB1165104A GB05875/68A GB1587568A GB1165104A GB 1165104 A GB1165104 A GB 1165104A GB 05875/68 A GB05875/68 A GB 05875/68A GB 1587568 A GB1587568 A GB 1587568A GB 1165104 A GB1165104 A GB 1165104A
Authority
GB
United Kingdom
Prior art keywords
pseudotropine
dimethyl
benzoic acid
acid ester
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB05875/68A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyesult Gyogyszer es Tapszergyar
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyesult Gyogyszer es Tapszergyar
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyesult Gyogyszer es Tapszergyar, Egyt Gyogyszervegyeszeti Gyar filed Critical Egyesult Gyogyszer es Tapszergyar
Publication of GB1165104A publication Critical patent/GB1165104A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1,165,104. Pseudotropine-3,4,5-trimethoxy benzoic acid ester. EGYESULT GYOGYSZER ES TAPSZERGYAR. 2 April, 1968 [12 April, 1967], No. 15875/68. Heading C2C. Novel compounds of the formula are prepared by reacting 1,5-dimethyl-pseudotropine or a reactive derivative thereof, preferably its hydrochloride with 3,4,5 -trimethoxy benzoic acid anhydride or acid halide, preferably chloride or 1,5-dimethyl pseudotropine with a lower alkyl ester of 3,4,5-trimethoxy benzoic acid. Pharmaceutical compounds of Formula I, in the form of acid addition salts or quaternary ammonium compounds alone or combined with other excipients and carriers can be used as endoanesthetic agents and are administered intravenously.
GB05875/68A 1967-04-12 1968-04-02 0,5-Dimethyl Pseudotropine 3,4,5-Trimethoxybenzoic Acid Ester and its Derivatives Expired GB1165104A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUEE001379 1967-04-12

Publications (1)

Publication Number Publication Date
GB1165104A true GB1165104A (en) 1969-09-24

Family

ID=10995228

Family Applications (1)

Application Number Title Priority Date Filing Date
GB05875/68A Expired GB1165104A (en) 1967-04-12 1968-04-02 0,5-Dimethyl Pseudotropine 3,4,5-Trimethoxybenzoic Acid Ester and its Derivatives

Country Status (10)

Country Link
AT (1) AT281306B (en)
BE (1) BE713630A (en)
CH (1) CH512489A (en)
DE (1) DE1770172A1 (en)
DK (1) DK116596B (en)
FR (1) FR1558897A (en)
GB (1) GB1165104A (en)
IL (1) IL29760A (en)
NL (1) NL6805021A (en)
SE (1) SE327710B (en)

Also Published As

Publication number Publication date
DK116596B (en) 1970-01-26
FR1558897A (en) 1969-02-28
NL6805021A (en) 1968-10-14
BE713630A (en) 1968-10-14
SE327710B (en) 1970-08-31
CH512489A (en) 1971-09-15
AT281306B (en) 1970-05-11
IL29760A (en) 1972-02-29
DE1770172A1 (en) 1972-03-09
IL29760A0 (en) 1968-06-20

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
435 Patent endorsed 'licences of right' on the date specified (sect. 35/1949)
PLNP Patent lapsed through nonpayment of renewal fees