GB1164838A - New Peptides having an Acth-Action and Process for their Manufacture - Google Patents
New Peptides having an Acth-Action and Process for their ManufactureInfo
- Publication number
- GB1164838A GB1164838A GB5089666A GB5089666A GB1164838A GB 1164838 A GB1164838 A GB 1164838A GB 5089666 A GB5089666 A GB 5089666A GB 5089666 A GB5089666 A GB 5089666A GB 1164838 A GB1164838 A GB 1164838A
- Authority
- GB
- United Kingdom
- Prior art keywords
- boc
- lys
- val
- pro
- tyr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 3
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 108010015792 glycyllysine Proteins 0.000 abstract 2
- 108010009962 valyltyrosine Proteins 0.000 abstract 2
- 239000000275 Adrenocorticotropic Hormone Substances 0.000 abstract 1
- 101800000414 Corticotropin Proteins 0.000 abstract 1
- 235000019766 L-Lysine Nutrition 0.000 abstract 1
- 125000002059 L-arginyl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H] 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- FUOGXAQMNJMBFG-WPRPVWTQSA-N Pro-Val-Gly Chemical compound OC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1 FUOGXAQMNJMBFG-WPRPVWTQSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001370 alpha-amino acid derivatives Chemical class 0.000 abstract 1
- 235000008206 alpha-amino acids Nutrition 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- IDLFZVILOHSSID-OVLDLUHVSA-N corticotropin Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)NC(=O)[C@@H](N)CO)C1=CC=C(O)C=C1 IDLFZVILOHSSID-OVLDLUHVSA-N 0.000 abstract 1
- 229960000258 corticotropin Drugs 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000003701 inert diluent Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000010647 peptide synthesis reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/695—Corticotropin [ACTH]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1563965A CH489471A (de) | 1965-11-12 | 1965-11-12 | Verfahren zur Herstellung neuer Peptide mit ACTH-Wirkung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1164838A true GB1164838A (en) | 1969-09-24 |
Family
ID=4410734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5089666A Expired GB1164838A (en) | 1965-11-12 | 1966-11-14 | New Peptides having an Acth-Action and Process for their Manufacture |
Country Status (8)
| Country | Link |
|---|---|
| AT (1) | AT270092B (cs) |
| BE (1) | BE689576A (cs) |
| BR (1) | BR6684477D0 (cs) |
| CH (1) | CH489471A (cs) |
| DE (1) | DE1543503A1 (cs) |
| FR (1) | FR1506515A (cs) |
| GB (1) | GB1164838A (cs) |
| NL (1) | NL6615967A (cs) |
-
1965
- 1965-11-12 CH CH1563965A patent/CH489471A/de not_active IP Right Cessation
-
1966
- 1966-11-08 DE DE19661543503 patent/DE1543503A1/de active Pending
- 1966-11-08 FR FR82874A patent/FR1506515A/fr not_active Expired
- 1966-11-10 BE BE689576D patent/BE689576A/xx unknown
- 1966-11-11 AT AT1045966A patent/AT270092B/de active
- 1966-11-11 BR BR18447766A patent/BR6684477D0/pt unknown
- 1966-11-11 NL NL6615967A patent/NL6615967A/xx unknown
- 1966-11-14 GB GB5089666A patent/GB1164838A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH489471A (de) | 1970-04-30 |
| BR6684477D0 (pt) | 1973-12-26 |
| NL6615967A (cs) | 1967-05-16 |
| BE689576A (cs) | 1967-05-10 |
| AT270092B (de) | 1969-04-10 |
| DE1543503A1 (de) | 1969-09-04 |
| FR1506515A (fr) | 1967-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |