GB1159490A - Improvements in Acylated Steroids - Google Patents

Improvements in Acylated Steroids

Info

Publication number
GB1159490A
GB1159490A GB30019/68A GB3001968A GB1159490A GB 1159490 A GB1159490 A GB 1159490A GB 30019/68 A GB30019/68 A GB 30019/68A GB 3001968 A GB3001968 A GB 3001968A GB 1159490 A GB1159490 A GB 1159490A
Authority
GB
United Kingdom
Prior art keywords
compounds
fluorine
hydroxy
hydroxyprogesterone
progesterone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB30019/68A
Other languages
English (en)
Inventor
John Rosindale Housley
Peter Oxley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Pure Drug Co Ltd
Original Assignee
Boots Pure Drug Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Pure Drug Co Ltd filed Critical Boots Pure Drug Co Ltd
Publication of GB1159490A publication Critical patent/GB1159490A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/913—Aspergillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/939—Rhizopus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB30019/68A 1966-02-09 1966-02-09 Improvements in Acylated Steroids Expired GB1159490A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB571966 1966-02-09
GB56249/66A GB1158492A (en) 1966-02-09 1966-02-09 Improvements in Acylated Steroids
GB3001868 1966-02-09

Publications (1)

Publication Number Publication Date
GB1159490A true GB1159490A (en) 1969-07-23

Family

ID=27254686

Family Applications (2)

Application Number Title Priority Date Filing Date
GB56249/66A Expired GB1158492A (en) 1966-02-09 1966-02-09 Improvements in Acylated Steroids
GB30019/68A Expired GB1159490A (en) 1966-02-09 1966-02-09 Improvements in Acylated Steroids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB56249/66A Expired GB1158492A (en) 1966-02-09 1966-02-09 Improvements in Acylated Steroids

Country Status (8)

Country Link
US (1) US3506694A (https=)
CH (1) CH487134A (https=)
DK (1) DK117896B (https=)
FR (2) FR1513708A (https=)
GB (2) GB1158492A (https=)
NL (1) NL151630B (https=)
NO (1) NO127577B (https=)
SE (1) SE342239B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2153357A (en) * 1984-02-03 1985-08-21 Roussel Uclaf Production of prednisone derivatives
CN107556357A (zh) * 2017-09-28 2018-01-09 湖南科瑞生物制药股份有限公司 丙酸地泼罗酮的制备方法

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856956A (en) * 1967-02-02 1974-12-24 Boots Pure Drug Co Ltd 17-acyloxysteroids and their manufacture
JP2655190B2 (ja) * 1989-06-21 1997-09-17 エスエス製薬 株式会社 コルチコステロイド含有軟膏剤
SI1775305T1 (sl) 2000-08-05 2015-01-30 Glaxo Group Limited S-fluorometil ester 6alfa,9alfa-difluoro-17alfa-((2-furanilkarboksil)oksi)- 11beta-hidroksi-16alfa-metil-3-okso-androst-1,4-dien-17-karbotiojske kisline kot protivnetno sredstvo
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
KR100831534B1 (ko) * 2001-04-30 2008-05-22 글락소 그룹 리미티드 17.알파 위치에 시클릭 에스테르기를 지닌 항염증성의안드로스탄의 17.베타.-카르보티오에이트 에스테르 유도체
ES2307751T3 (es) * 2001-06-12 2008-12-01 Glaxo Group Limited Nuevos esteres heterociclicos centi-inflamatorios 17 alfa de derivados 17 beta de carbotioato de androstano.
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US7825147B2 (en) * 2003-08-29 2010-11-02 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-IV
WO2005051931A2 (en) * 2003-11-26 2005-06-09 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
US20080009535A1 (en) * 2004-08-30 2008-01-10 Sarala Balachandran Inhibitors of phosphodiesterase type-IV
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
WO2007031838A1 (en) 2005-09-16 2007-03-22 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
AU2006305619A1 (en) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Pharmaceutical compositions of muscarinic receptor antagonists
BRPI0617673C1 (pt) * 2005-10-19 2012-05-22 Ranbaxy Lab Ltd composições de inibidores de fosfodiesterase do tipo iv
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
EP2066661A2 (en) * 2006-09-22 2009-06-10 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
EA200900472A1 (ru) * 2006-09-22 2009-10-30 Ранбакси Лабораторис Лимитед Ингибиторы фосфодиэстеразы iv типа
US20080207659A1 (en) * 2007-02-15 2008-08-28 Asit Kumar Chakraborti Inhibitors of phosphodiesterase type 4
US20110130403A1 (en) * 2007-03-14 2011-06-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors
NZ579645A (en) 2007-03-14 2012-01-12 Ranbaxy Lab Ltd Pyrazolo (3, 4-b) pyridine derivatives as phosphodiesterase inhibitors
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
CN102372762B (zh) * 2010-08-18 2012-11-07 天津金耀集团有限公司 一种孕甾11位β羟基合成的工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2923721A (en) * 1955-12-13 1960-02-02 Lab Francais Chimiotherapie Method of preparing 3-keto delta1, 4 steroids
US2902410A (en) * 1957-09-26 1959-09-01 Upjohn Co Process for the 1,2-dehydrogenation of a steroid with septomyxa

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2153357A (en) * 1984-02-03 1985-08-21 Roussel Uclaf Production of prednisone derivatives
CN107556357A (zh) * 2017-09-28 2018-01-09 湖南科瑞生物制药股份有限公司 丙酸地泼罗酮的制备方法

Also Published As

Publication number Publication date
GB1158492A (en) 1969-07-16
US3506694A (en) 1970-04-14
FR6137M (https=) 1968-06-24
FR1513708A (fr) 1968-02-16
DK117896B (da) 1970-06-15
NO127577B (https=) 1973-07-16
DE1618095A1 (de) 1971-03-25
NL6701919A (https=) 1967-08-10
NL151630B (nl) 1976-12-15
SE342239B (https=) 1972-01-31
DE1618095B2 (de) 1975-09-18
CH487134A (fr) 1970-03-15

Similar Documents

Publication Publication Date Title
GB1159490A (en) Improvements in Acylated Steroids
GB1329387A (en) Selective microbiological preparation of androst-4-ene 3,17-dione
GB1127746A (en) Novel process for preparing unsaturated steroids
GB1571913A (en) Process for the manufacture of -androstene-3,17-dione derivatives
GB1248938A (en) Improvements in or relating to gem-difluoro steroids
GB1365469A (en) Steroids of the d-homopregnane series
Charney et al. Microbiological transformation of steroids—XI: the action of corynebacterium simplex on non-corticoid steroid substrates
US2877240A (en) 6-fluoro-17beta-hydroxy-17alpha-lower aliphatic hydrocarbon-1, 4-androstadienes and 6-fluoro-17alpha-lower aliphatic hydrocarbon estradiols
US2867637A (en) 6alpha methyl, 9alpha f, 17alpha oh 1, 4 pregnadiene compounds
IE44308B1 (en) Process for the manufacture of 5-androsten-17-one derivatives and their use
US4033995A (en) D-homo steroids
US3763145A (en) Halogenosteroids
US3396161A (en) Process for the manufacture of 6alpha, 9alpha-difluoro-1, 4-pregnadiene-3, 20-diones
US3126376A (en) Fluorinated anbrostenes and inter-
GB1130115A (en) 16-methyl-4-pregnen-3ªß-ol-20-ones and their preparation
GB1192061A (en) Steroidal 1,4-Dienes
GB1420892A (en) Racemic 13beta-ethyl-3-methoxy-8,14-socogona-1,3,5-10,8- tetraen-17beta-ol-14-one and a process for the preparation thereof
GB1410767A (en) Anrostane derivatives
GB1281483A (en) Method for preparing corticosteroids
GB959794A (en) Improvements in or relating to steroids
GB1291036A (en) 7-methyl-7-hydroxy-steroids
GB1101116A (en) Steroidal 2ª‡-carboxylic acids and esters
GB1480038A (en) D-homosteroids
GB1247021A (en) 4-oxa-androstanes and a process for the manufacture thereof
GB1211356A (en) Process for the production of 17-ketosteroids

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE Patent expired