GB1156408A - Process for the Production of Halopyrimidines - Google Patents

Process for the Production of Halopyrimidines

Info

Publication number
GB1156408A
GB1156408A GB4990067A GB4990067A GB1156408A GB 1156408 A GB1156408 A GB 1156408A GB 4990067 A GB4990067 A GB 4990067A GB 4990067 A GB4990067 A GB 4990067A GB 1156408 A GB1156408 A GB 1156408A
Authority
GB
United Kingdom
Prior art keywords
aryl
alkyl
hydrogen
halogen atom
aralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4990067A
Inventor
Kurt Findeisen
Rudolf Braden
Hans Holtschmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB1156408A publication Critical patent/GB1156408A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Movable Scaffolding (AREA)

Abstract

1,156,408. Halopyrimidines. FARBENFABRIKEN BAYER A.G. 2 Nov., 1967 [20 April, 1967], No. 49900/67. Heading C2C. Halopyrimidines are produced by reacting substituted acetonitriles of the formula R-CR 1 R 2 -C#N, wherein R is a hydrogen or halogen atom or a nitro, alkyl, aralkyl, cycloalkyl, aryl, cyano, alkoxy, carboxylic acyl, carboxylic acyloxy, carbalkoxy, or alkyl- or aryl-sulphonyl group and each of R 1 and R 2 is a hydrogen or halogen atom, with isocyanide dichlorides of the formula R 3 -R 4 R 5 -N = CCl 2 , wherein R 3 is a hydrogen or halogen atom or an alkyl, aralkyl, cycloalkyl, aryl or aromatic heterocyclic group and each of R 4 and R 5 is a hydrogen or halogen atom, provided that at least two of the radicals R-R 5 represent halogen, the alkyl, aralkyl, aryl and hetero radicals being optionally substituted. The reaction may be carried out in the presence of a catalyst, e.g. ferric chloride, and/or an inert solvent or diluent.
GB4990067A 1967-04-20 1967-11-02 Process for the Production of Halopyrimidines Expired GB1156408A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1967F0052193 DE1670854B2 (en) 1967-04-20 1967-04-20 PROCESS FOR THE PREPARATION OF 2,4,6-TRICHLOROPYRIMIDINES

Publications (1)

Publication Number Publication Date
GB1156408A true GB1156408A (en) 1969-06-25

Family

ID=7105251

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4990067A Expired GB1156408A (en) 1967-04-20 1967-11-02 Process for the Production of Halopyrimidines

Country Status (10)

Country Link
AT (1) AT281034B (en)
BE (1) BE707203A (en)
CH (1) CH503034A (en)
DE (1) DE1670854B2 (en)
DK (1) DK117492B (en)
ES (1) ES347176A1 (en)
GB (1) GB1156408A (en)
NL (1) NL6715452A (en)
NO (1) NO121341B (en)
SE (1) SE332989B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI895821A0 (en) * 1988-12-07 1989-12-05 Wellcome Found PHARMACEUTICAL ACTIVE CNS FOERENINGAR.

Also Published As

Publication number Publication date
DE1670854B2 (en) 1977-04-28
ES347176A1 (en) 1969-01-16
SE332989B (en) 1971-03-01
NO121341B (en) 1971-02-15
DK117492B (en) 1970-05-04
AT281034B (en) 1970-05-11
NL6715452A (en) 1968-10-21
CH503034A (en) 1971-02-15
DE1670854A1 (en) 1971-03-18
BE707203A (en) 1968-05-28

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