ES347176A1 - Process for the Production of Halopyrimidines - Google Patents

Process for the Production of Halopyrimidines

Info

Publication number
ES347176A1
ES347176A1 ES347176A ES347176A ES347176A1 ES 347176 A1 ES347176 A1 ES 347176A1 ES 347176 A ES347176 A ES 347176A ES 347176 A ES347176 A ES 347176A ES 347176 A1 ES347176 A1 ES 347176A1
Authority
ES
Spain
Prior art keywords
aryl
alkyl
hydrogen
halogen atom
aralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES347176A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES347176A1 publication Critical patent/ES347176A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Movable Scaffolding (AREA)

Abstract

Halopyrimidines are produced by reacting substituted acetonitriles of the formula R-CR 1 R 2 -C#N, wherein R is a hydrogen or halogen atom or a nitro, alkyl, aralkyl, cycloalkyl, aryl, cyano, alkoxy, carboxylic acyl, carboxylic acyloxy, carbalkoxy, or alkyl- or aryl-sulphonyl group and each of R 1 and R 2 is a hydrogen or halogen atom, with isocyanide dichlorides of the formula R 3 -R 4 R 5 -N = CCl 2 , wherein R 3 is a hydrogen or halogen atom or an alkyl, aralkyl, cycloalkyl, aryl or aromatic heterocyclic group and each of R 4 and R 5 is a hydrogen or halogen atom, provided that at least two of the radicals R-R 5 represent halogen, the alkyl, aralkyl, aryl and hetero radicals being optionally substituted. The reaction may be carried out in the presence of a catalyst, e.g. ferric chloride, and/or an inert solvent or diluent.
ES347176A 1967-04-20 1967-11-15 Process for the Production of Halopyrimidines Expired ES347176A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1967F0052193 DE1670854B2 (en) 1967-04-20 1967-04-20 PROCESS FOR THE PREPARATION OF 2,4,6-TRICHLOROPYRIMIDINES

Publications (1)

Publication Number Publication Date
ES347176A1 true ES347176A1 (en) 1969-01-16

Family

ID=7105251

Family Applications (1)

Application Number Title Priority Date Filing Date
ES347176A Expired ES347176A1 (en) 1967-04-20 1967-11-15 Process for the Production of Halopyrimidines

Country Status (10)

Country Link
AT (1) AT281034B (en)
BE (1) BE707203A (en)
CH (1) CH503034A (en)
DE (1) DE1670854B2 (en)
DK (1) DK117492B (en)
ES (1) ES347176A1 (en)
GB (1) GB1156408A (en)
NL (1) NL6715452A (en)
NO (1) NO121341B (en)
SE (1) SE332989B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI895821A0 (en) * 1988-12-07 1989-12-05 Wellcome Found PHARMACEUTICAL ACTIVE CNS FOERENINGAR.

Also Published As

Publication number Publication date
NO121341B (en) 1971-02-15
DE1670854A1 (en) 1971-03-18
CH503034A (en) 1971-02-15
DE1670854B2 (en) 1977-04-28
BE707203A (en) 1968-05-28
AT281034B (en) 1970-05-11
SE332989B (en) 1971-03-01
DK117492B (en) 1970-05-04
GB1156408A (en) 1969-06-25
NL6715452A (en) 1968-10-21

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