GB1152679A - Pharmaceutical and Veterinary Preparations - Google Patents
Pharmaceutical and Veterinary PreparationsInfo
- Publication number
- GB1152679A GB1152679A GB8183/67A GB818367A GB1152679A GB 1152679 A GB1152679 A GB 1152679A GB 8183/67 A GB8183/67 A GB 8183/67A GB 818367 A GB818367 A GB 818367A GB 1152679 A GB1152679 A GB 1152679A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lower alkyl
- hydrogen atom
- alkyl
- carbon atoms
- tris
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/168—Steroids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
- A23K20/126—Lactones
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/184—Hormones
Abstract
1,152,679. Pharmaceutical and veterinary preparations. COMMERCIAL SOLVENTS CORP. 21 Feb., 1967 [2 March, 1966; 10 Feb., 1967], No. 8183/67. Heading A5B. Pharmaceutical and veterinary compositions for fertility control, estrogen therapy and increasing anabolic activity comprise as active ingredients:-(A) a compound having the structure: wherein R is a hydrogen atom, lower alkyl (i.e. having from I to 6 carbon atoms), lower saturated acyclic acyl or benzyl; B is -CH=CH-; wherein R<SP>1</SP> is a hydrogen atom, fluoride, hydroxyl or -N(R<SP>2</SP>) 2 wherein R<SP>2</SP> is a hydrogen atom, alkyl having from 1 to 15 carbon atoms; monocyclic aryl or an aralkyl having from 1 to 15 carbon atoms; Z is >C=O, -CH 2 -C-, -C-CH 2 -, >CHNHOH, >C=NOH or >C=NNHR<SP>5</SP> wherein R<SP>3</SP> is a hydrogen atom, a hydroxyl, a halogen atom, -OR<SP>6</SP> or NHR<SP>7</SP>, R<SP>6</SP> is lower alkyl, benzyl or lower saturated acyclic acyl and R<SP>7</SP> is a hydrogen atom, lower alkyl or monocyclic aryl; R<SP>4</SP> is alkyl, aryl, aralkyl, nitromethyl, aminomethyl, ethynyl, cyano, or -R<SP>9</SP>COOR<SP>8</SP> wherein R<SP>8</SP> is lower alkyl and R<SP>9</SP> is lower alkylene; X is a halogen atom, nitromethyl or aminomethyl; R<SP>5</SP> is lower alkyl, a hydrogen atom, carbamyl or monocyclic aryl; and E is an alkylene having from 2 to 3 carbon atoms; with the proviso that when Z is >CH 2 , >CHNHR<SP>7</SP> or >CHNHOH, B is -CH 2 -CH 2 - and is a cyclohexane ring or a benzene ring of the formula . wherein X and Y are a hydrogen atom, nitro, amino, diazonium radical, cyano, hydroxyl, aryl, alkenyl, alkyl, acyl; alkoxy, carboxy, -SQ 3 H, -SO 3 R<SP>10</SP>, -SO 2 Cl or -SO 2 NHR<SP>11</SP> wherein R<SP>10</SP> is lower alkyl and R<SP>11</SP> is a hydrogen atom, an alkyl having from 1 to 20 carbon atoms, monocyclic aryl or a halogen atom, with the proviso that when one of X and Y is carboxy the other of X and Y is a hydrogen atom, that R is lower alkyl or benzyl when X or Y is -SO 2 Cl, and that when the radical of formula XI is. a cyclohexane ring, B is -CH 2 -CH 2 - and Z is >CH 2 or >CHOR<SP>6</SP>, and (B) benzestrol; dinestrol; estrone; diethylstilbestrol or a derivative thereof as represented by the structure: wherein A is or. R is H or lower alkyl; Z is H, -PO 3 , -SO 3 R<SP>1</SP> or O where R<SP>1</SP> is an aliphatic hydrocarbon radical having from 1 to 20 carbon atoms; n is 0 or 1 and when 0, R is H; estradiol or a derivative thereof as. represented by. the structure: . wherein Z<SP>1</SP> is H, benzoyl, R or where R is lower alkyl; R<SP>1</SP> is H or lower alkyl; n and n<SP>1</SP> are 0 or 1 , and when 0, C#CR<SP>1</SP> is H; a progestogen having the structure: wherein R is H or lower alkyl; Q is -OH or and R is a lower alkyl; Q<SP>1</SP> is H, acetoxy, O # -C#CH, -C#C-R or -CR, wherein R is lower alkyl; Y is lower alkyl or a halogen atom and n and .n<SP>1</SP> are 0 to 1 when n is 0,. R is H and when n<SP>1</SP> is 0, Y is H; or a tris-phenyl ethylene having, the structure wherein X is OH, lower alkoxy or acyloxy and Y<SP>1</SP> is a halogen atom or a hydrogen atom. The ingredient (B) may comprise, as diethylstilbestrol derivatives, diethylstilbestrol dipropionate, monomethyl ; ether,. dimethyl ether, dipalmitate, diphosphate-and disulphate, hexestrol and promethestrol dipropionate; as estradiol derivatives, estradiol benzoate and cyclopentyl.. propionate, estradioldipropionate, estriol , ethinyl estradiol and ethinyl estradiol-3- methyl ether; as progestogens, progesterone, dimethisterone, 17α-ethinyl-17#-hydroxy-5 (10) estren-3-one (norethynodrel), norethindrone. ohlormadinone acetate and medroxyprogestrone acetate; and as tris-phenyl ethylene compounds, tris(p-methoxy phenyl)ethylene, tris (p-hydroxyphenyl)ethylene and tris-(p-methoxyphenyl)-ohloro-ethylene. The compositions may be administered orally in the form of pressed or coated tablets, capsules, pills, syrups, solutions or suspensions or parenterally as sterile aqueous solutions or suspensions in oily media. The composition may also be in the form of an animal feed composition also comprising ediblenutrient' carriers and' conventional excipients. '
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53103966A | 1966-03-02 | 1966-03-02 | |
US61507367A | 1967-02-10 | 1967-02-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1152679A true GB1152679A (en) | 1969-05-21 |
Family
ID=27063446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB8183/67A Expired GB1152679A (en) | 1966-03-02 | 1967-02-21 | Pharmaceutical and Veterinary Preparations |
Country Status (8)
Country | Link |
---|---|
BE (1) | BE694847A (en) |
CA (1) | CA919594A (en) |
DE (1) | DE1692409B1 (en) |
DK (1) | DK121986B (en) |
FR (1) | FR8353M (en) |
GB (1) | GB1152679A (en) |
IL (1) | IL27457A (en) |
NL (1) | NL6702893A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2180674A1 (en) * | 1972-03-16 | 1973-11-30 | Pedigree Petfoods Ltd | |
EP0015637A1 (en) * | 1979-03-02 | 1980-09-17 | American Cyanamid Company | Method for enhancing growth rate and feed efficiency of ruminants |
EP0280545A2 (en) * | 1987-02-27 | 1988-08-31 | IMCERA Group Inc. | Estriol growth promotant |
US7767708B2 (en) | 1998-11-04 | 2010-08-03 | Schering-Plough Animal Health Corp. | Growth stimulant compositions |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE794137A (en) * | 1972-01-20 | 1973-07-17 | Roussel Uclaf | POULTRY FOOD ADDITIVES AND CONTAINING FOOD COMPOSITIONS |
FR2183555B1 (en) * | 1972-05-10 | 1975-06-20 | Roussel Uclaf |
-
0
- CA CA919594A patent/CA919594A/en not_active Expired
-
1967
- 1967-02-19 IL IL27457A patent/IL27457A/en unknown
- 1967-02-21 GB GB8183/67A patent/GB1152679A/en not_active Expired
- 1967-02-24 NL NL6702893A patent/NL6702893A/xx unknown
- 1967-02-25 DE DE19671692409 patent/DE1692409B1/en not_active Withdrawn
- 1967-03-01 DK DK108367AA patent/DK121986B/en unknown
- 1967-03-01 FR FR96934A patent/FR8353M/fr not_active Expired
- 1967-03-01 BE BE694847D patent/BE694847A/xx unknown
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2180674A1 (en) * | 1972-03-16 | 1973-11-30 | Pedigree Petfoods Ltd | |
EP0015637A1 (en) * | 1979-03-02 | 1980-09-17 | American Cyanamid Company | Method for enhancing growth rate and feed efficiency of ruminants |
EP0280545A2 (en) * | 1987-02-27 | 1988-08-31 | IMCERA Group Inc. | Estriol growth promotant |
EP0280545A3 (en) * | 1987-02-27 | 1990-03-07 | International Minerals And Chemical Corporation | Estriol growth promotant |
US7767708B2 (en) | 1998-11-04 | 2010-08-03 | Schering-Plough Animal Health Corp. | Growth stimulant compositions |
US7999005B2 (en) | 1998-11-04 | 2011-08-16 | Schering-Plough Animal Health Corporation | Growth stimulant compositions |
Also Published As
Publication number | Publication date |
---|---|
DK121986B (en) | 1971-12-27 |
FR8353M (en) | 1971-02-08 |
CA919594A (en) | 1973-01-23 |
IL27457A (en) | 1971-03-24 |
DE1692409B1 (en) | 1971-09-16 |
NL6702893A (en) | 1967-09-04 |
BE694847A (en) | 1967-08-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |