GB1149638A - Pyrazinimidoylguanidines - Google Patents

Pyrazinimidoylguanidines

Info

Publication number
GB1149638A
GB1149638A GB23385/66A GB2338566A GB1149638A GB 1149638 A GB1149638 A GB 1149638A GB 23385/66 A GB23385/66 A GB 23385/66A GB 2338566 A GB2338566 A GB 2338566A GB 1149638 A GB1149638 A GB 1149638A
Authority
GB
United Kingdom
Prior art keywords
amino
formula
reacting
prepared
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB23385/66A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1149638A publication Critical patent/GB1149638A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GB23385/66A 1965-10-04 1966-05-25 Pyrazinimidoylguanidines Expired GB1149638A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US492868A US3274192A (en) 1965-10-04 1965-10-04 Derivatives of pyrazine and a method for their preparation

Publications (1)

Publication Number Publication Date
GB1149638A true GB1149638A (en) 1969-04-23

Family

ID=23957936

Family Applications (1)

Application Number Title Priority Date Filing Date
GB23385/66A Expired GB1149638A (en) 1965-10-04 1966-05-25 Pyrazinimidoylguanidines

Country Status (12)

Country Link
US (1) US3274192A (https=)
BE (1) BE682664A (https=)
BR (1) BR6680520D0 (https=)
CH (1) CH469011A (https=)
DE (1) DE1620010A1 (https=)
DK (1) DK111892B (https=)
ES (1) ES328363A1 (https=)
FR (2) FR1560217A (https=)
GB (1) GB1149638A (https=)
IL (1) IL25802A (https=)
NL (1) NL6608466A (https=)
SE (1) SE329622B (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4402959A (en) * 1980-06-02 1983-09-06 Merck & Co., Inc. Antimicrobial compositions
US4517186A (en) * 1982-09-30 1985-05-14 Merck & Co., Inc. 2-Amino-3,5-dicyano-6-(substituted)pyrazine antimicrobial compounds
US4518599A (en) * 1982-09-30 1985-05-21 Merck & Co., Inc. 2-Amino-3-cyano-5-halo-6-(substituted)pyrazine
US4507299A (en) * 1982-12-27 1985-03-26 Merck & Co., Inc. N-[2-amino-5-halo-6-(substituted)-3-pyrazinyl)-methylene]amine antimicrobial compounds
US4512991A (en) * 1982-12-27 1985-04-23 Merck & Co., Inc. 3-Acyl-2-amino-5-halo-6-(substituted)pyrazine antimicrobial compounds
US4442096A (en) * 1982-12-27 1984-04-10 Merck & Co., Inc. 2-(Substituted)amino-3-cyano-5-halo-6-(substituted)-pyrazine antimicrobial compounds, compositions and use
US4442095A (en) * 1982-12-27 1984-04-10 Merck & Co., Inc. N-[(5-Halo-2,6-(substituted)pyrazinyl)methylene]amine antimicrobial compounds, compositions and use
US4442097A (en) * 1982-12-27 1984-04-10 Merck & Co., Inc. 3-Acyl-2-(substituted) amino-5-halo-6-(substituted) pyrazine antimicrobial compounds, compositions and use
US4481202A (en) * 1982-12-27 1984-11-06 Merek & Co., Inc. 2-Amino-3-carboxylate-5-halo-6-(substituted)pyrazine antimicrobial compounds
US4479953A (en) * 1983-08-25 1984-10-30 Merck & Co., Inc. Pyrazine aldimine compounds as antimicrobial agents
JP4523093B2 (ja) * 1999-09-20 2010-08-11 広栄化学工業株式会社 ２−アミノ−ブロモピラジン類の製造方法
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
RU2018138195A (ru) 2012-12-17 2018-12-18 Пэрион Сайенсиз, Инк. Соединения 3,5-диамино-6-хлор-n-(n-(4- фенилбутил)карбамимидоил)пиразин-2-карбоксамида
SG10201708931XA (en) 2012-12-17 2017-12-28 Parion Sciences Inc Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Also Published As

Publication number Publication date
BR6680520D0 (pt) 1973-12-26
NL6608466A (https=) 1967-04-05
CH469011A (de) 1969-02-28
DK111892B (da) 1968-10-21
FR1560217A (https=) 1969-03-21
ES328363A1 (es) 1967-04-01
BE682664A (https=) 1966-12-16
SE329622B (https=) 1970-10-19
DE1620010A1 (de) 1970-02-12
US3274192A (en) 1966-09-20
IL25802A (en) 1970-05-21
FR5811M (https=) 1968-02-19

Similar Documents

Publication Publication Date Title
GB1149638A (en) Pyrazinimidoylguanidines
GB1132082A (en) The manufacture of pyrimidine derivatives
GB1309835A (en) Trialkoxy-quinazolines
GB1163324A (https=)
GB1382782A (en) Alkylarylketones processes for their preparation and compositions incorporating them
GB1262965A (en) Butyrophenones
GB1369248A (en) Amides the preparation thereof and their use in pharmacjeutical compositions
GB1429141A (en) 1-substituted pyrazol-5-ones their production and their medicinal use
GB1052509A (https=)
GB1457038A (en) Amino derivatives of 1,4-benzodioxan
GB1460761A (en) Dihalogenophenol derivatives
GB1178708A (en) Improvements in or relating to thienobenzothiazepine derivatives
GB1290381A (https=)
GB1239567A (https=)
GB1450452A (en) Derivatives of pyrazolo 3,4-2,3- pyrido 4,5-e- b-benzo-1,5- diazepinones
SE7412147L (https=)
GB1154548A (en) Preparation of 1,2,5,-Thiadiazole Derivatives
GB1298642A (en) Halopyrazoles
GB1197691A (en) Substituted Thienoimidazoles
GB1299421A (en) 3-substituted amino-6-hydrazino-pyridazines
GB1173342A (en) Process for the preparation of Pyrazinoylguanidines and Pyrazinamido Guanidines and Intermediates produced in the process
GB1254270A (en) Benzoxazepine derivatives
GB1061335A (en) Penicillins
GB1135340A (en) Benzodioxole derivatives
GB1359223A (en) Benzodiazepine derivatives processes for producing them 'and compositions containing them