GB1147698A - New tetracycline derivatives - Google Patents
New tetracycline derivativesInfo
- Publication number
- GB1147698A GB1147698A GB5627566A GB5627566A GB1147698A GB 1147698 A GB1147698 A GB 1147698A GB 5627566 A GB5627566 A GB 5627566A GB 5627566 A GB5627566 A GB 5627566A GB 1147698 A GB1147698 A GB 1147698A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compounds
- tetracyclines
- dec
- bis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000004098 Tetracycline Substances 0.000 title abstract 4
- 235000019364 tetracycline Nutrition 0.000 title abstract 4
- 150000003522 tetracyclines Chemical class 0.000 title abstract 4
- 229960002180 tetracycline Drugs 0.000 title abstract 2
- 229930101283 tetracycline Natural products 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229940040944 tetracyclines Drugs 0.000 abstract 2
- 239000004100 Oxytetracycline Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000005263 alkylenediamine group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 abstract 1
- CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 abstract 1
- 239000003701 inert diluent Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229960000625 oxytetracycline Drugs 0.000 abstract 1
- IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 abstract 1
- 235000019366 oxytetracycline Nutrition 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 abstract 1
- 229940072172 tetracycline antibiotic Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR42306A FR1482843A (fr) | 1965-12-15 | 1965-12-15 | Nouveaux dérivés de tétracycline et leur procédé de préparation |
| FR53289A FR5668M (enrdf_load_stackoverflow) | 1965-12-15 | 1966-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1147698A true GB1147698A (en) | 1969-04-02 |
Family
ID=26167762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5627566A Expired GB1147698A (en) | 1965-12-15 | 1966-12-15 | New tetracycline derivatives |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE690632A (enrdf_load_stackoverflow) |
| DE (1) | DE1568970A1 (enrdf_load_stackoverflow) |
| FR (2) | FR1482843A (enrdf_load_stackoverflow) |
| GB (1) | GB1147698A (enrdf_load_stackoverflow) |
| LU (1) | LU52575A1 (enrdf_load_stackoverflow) |
| NL (2) | NL6617654A (enrdf_load_stackoverflow) |
-
0
- NL NL125840D patent/NL125840C/xx active
-
1965
- 1965-12-15 FR FR42306A patent/FR1482843A/fr not_active Expired
-
1966
- 1966-03-14 FR FR53289A patent/FR5668M/fr not_active Expired
- 1966-12-02 BE BE690632D patent/BE690632A/xx unknown
- 1966-12-12 LU LU52575D patent/LU52575A1/xx unknown
- 1966-12-13 DE DE19661568970 patent/DE1568970A1/de active Pending
- 1966-12-15 NL NL6617654A patent/NL6617654A/xx unknown
- 1966-12-15 GB GB5627566A patent/GB1147698A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE690632A (enrdf_load_stackoverflow) | 1967-06-02 |
| FR1482843A (fr) | 1967-06-02 |
| NL6617654A (enrdf_load_stackoverflow) | 1967-06-16 |
| LU52575A1 (enrdf_load_stackoverflow) | 1967-06-12 |
| DE1568970A1 (de) | 1970-04-02 |
| FR5668M (enrdf_load_stackoverflow) | 1968-01-02 |
| NL125840C (enrdf_load_stackoverflow) |
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