GB1145393A - Improvements in or relating to 17-‡-(alka-1',3'-diynyl)-steroids - Google Patents
Improvements in or relating to 17-‡-(alka-1',3'-diynyl)-steroidsInfo
- Publication number
- GB1145393A GB1145393A GB12301/67A GB1230167A GB1145393A GB 1145393 A GB1145393 A GB 1145393A GB 12301/67 A GB12301/67 A GB 12301/67A GB 1230167 A GB1230167 A GB 1230167A GB 1145393 A GB1145393 A GB 1145393A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroids
- diynyl
- alka
- hexadiynyl
- methoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000016087 ovulation Effects 0.000 abstract 1
- 230000001072 progestational effect Effects 0.000 abstract 1
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB12301/67A GB1145393A (en) | 1967-03-16 | 1967-03-16 | Improvements in or relating to 17-‡-(alka-1',3'-diynyl)-steroids |
| IE222/68A IE32433B1 (en) | 1967-03-16 | 1968-02-26 | Improvements in or relating to 17alpha(alka-1',3'-diynyl)-steroids |
| US708526A US3592828A (en) | 1967-03-16 | 1968-02-27 | 17 alpha-(1',3'-alkadiynyl)-17 beta-hydroxy (17 beta-alkoxy)-steroids |
| AT234068A AT282082B (de) | 1967-03-16 | 1968-03-08 | Verfahren zur Herstellung von neuen 17α-(1',3'-Akydiinyl)-steroiden |
| FR1573055D FR1573055A (enExample) | 1967-03-16 | 1968-03-08 | |
| BE712116D BE712116A (enExample) | 1967-03-16 | 1968-03-13 | |
| NL6803629A NL6803629A (enExample) | 1967-03-16 | 1968-03-14 | |
| CH385468A CH517722A (de) | 1967-03-16 | 1968-03-15 | Verfahren zur Herstellung von neuen 17a-(1',3'-Alkadiinyl)-steroiden |
| DE19681693004 DE1693004A1 (de) | 1967-03-16 | 1968-03-15 | 17a-(1',3'-Alkadiinyl)-steroide und Verfahren zu ihrer Herstellung |
| DK111568AA DK120947B (da) | 1967-03-16 | 1968-03-15 | Analogifremgangsmåde til fremstilling af 17α-(1',3'-alkadiynyl)-3β,17β-dihydroksy-4-androstener eller 17α-(1',3'-alkadiynyl)-3β,17β-dihydroksy-4-ostrener eller 3β-estere og 17β-alkylætere deraf. |
| SE03533/68A SE333374B (enExample) | 1967-03-16 | 1968-03-18 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB12301/67A GB1145393A (en) | 1967-03-16 | 1967-03-16 | Improvements in or relating to 17-‡-(alka-1',3'-diynyl)-steroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1145393A true GB1145393A (en) | 1969-03-12 |
Family
ID=10002012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12301/67A Expired GB1145393A (en) | 1967-03-16 | 1967-03-16 | Improvements in or relating to 17-‡-(alka-1',3'-diynyl)-steroids |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3592828A (enExample) |
| AT (1) | AT282082B (enExample) |
| BE (1) | BE712116A (enExample) |
| CH (1) | CH517722A (enExample) |
| DE (1) | DE1693004A1 (enExample) |
| DK (1) | DK120947B (enExample) |
| FR (1) | FR1573055A (enExample) |
| GB (1) | GB1145393A (enExample) |
| IE (1) | IE32433B1 (enExample) |
| NL (1) | NL6803629A (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1427141A (en) * | 1972-05-03 | 1976-03-10 | Bdh Pharmaceuticals Ltd | 17-alka-1,3-diynyl- steroids |
-
1967
- 1967-03-16 GB GB12301/67A patent/GB1145393A/en not_active Expired
-
1968
- 1968-02-26 IE IE222/68A patent/IE32433B1/xx unknown
- 1968-02-27 US US708526A patent/US3592828A/en not_active Expired - Lifetime
- 1968-03-08 AT AT234068A patent/AT282082B/de not_active IP Right Cessation
- 1968-03-08 FR FR1573055D patent/FR1573055A/fr not_active Expired
- 1968-03-13 BE BE712116D patent/BE712116A/xx unknown
- 1968-03-14 NL NL6803629A patent/NL6803629A/xx unknown
- 1968-03-15 CH CH385468A patent/CH517722A/de not_active IP Right Cessation
- 1968-03-15 DE DE19681693004 patent/DE1693004A1/de active Pending
- 1968-03-15 DK DK111568AA patent/DK120947B/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1693004A1 (de) | 1971-09-16 |
| AT282082B (de) | 1970-06-10 |
| US3592828A (en) | 1971-07-13 |
| CH517722A (de) | 1972-01-15 |
| IE32433B1 (en) | 1973-08-08 |
| DK120947B (da) | 1971-08-09 |
| IE32433L (en) | 1968-09-16 |
| NL6803629A (enExample) | 1968-09-17 |
| FR1573055A (enExample) | 1969-07-04 |
| BE712116A (enExample) | 1968-07-15 |
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