GB1145334A - 3-cyanomethylene-pregnenes and their manufacture and use - Google Patents
3-cyanomethylene-pregnenes and their manufacture and useInfo
- Publication number
- GB1145334A GB1145334A GB2395666A GB2395666A GB1145334A GB 1145334 A GB1145334 A GB 1145334A GB 2395666 A GB2395666 A GB 2395666A GB 2395666 A GB2395666 A GB 2395666A GB 1145334 A GB1145334 A GB 1145334A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pregnenes
- cyanomethylene
- manufacture
- activity
- gestogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- VDLILKOUSPEPBM-SXBNLZJNSA-N 2-[(8R,9S,10S,13R,14S,17R)-17-ethenyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-ylidene]acetonitrile Chemical class C(#N)C=C1CC2CC[C@H]3[C@@H]4CC[C@H](C=C)[C@]4(CC[C@@H]3[C@]2(CC1)C)C VDLILKOUSPEPBM-SXBNLZJNSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- BQTTYKVRRLHMQQ-ZBKBXNIDSA-N (8r,9s,10s,13r,14s,17r)-17-ethenyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one Chemical compound C1C(=O)CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)C=C)[C@@H]4[C@@H]3CCC21 BQTTYKVRRLHMQQ-ZBKBXNIDSA-N 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940124558 contraceptive agent Drugs 0.000 abstract 1
- 239000003433 contraceptive agent Substances 0.000 abstract 1
- RKHQGWMMUURILY-UHRZLXHJSA-N cortivazol Chemical class C([C@H]1[C@@H]2C[C@H]([C@]([C@@]2(C)C[C@H](O)[C@@H]1[C@@]1(C)C2)(O)C(=O)COC(C)=O)C)=C(C)C1=CC1=C2C=NN1C1=CC=CC=C1 RKHQGWMMUURILY-UHRZLXHJSA-N 0.000 abstract 1
- -1 cyanomethyl Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF0046172 | 1965-05-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1145334A true GB1145334A (en) | 1969-03-12 |
Family
ID=7100884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2395666A Expired GB1145334A (en) | 1965-05-28 | 1966-05-27 | 3-cyanomethylene-pregnenes and their manufacture and use |
Country Status (5)
| Country | Link |
|---|---|
| CH (1) | CH475223A (cs) |
| DE (1) | DE1518829C3 (cs) |
| DK (1) | DK123523B (cs) |
| FR (1) | FR1481592A (cs) |
| GB (1) | GB1145334A (cs) |
-
0
- FR FR1481592D patent/FR1481592A/fr not_active Expired
-
1965
- 1965-05-28 DE DE19651518829 patent/DE1518829C3/de not_active Expired
-
1966
- 1966-05-25 CH CH753366A patent/CH475223A/de not_active IP Right Cessation
- 1966-05-27 DK DK276166A patent/DK123523B/da unknown
- 1966-05-27 GB GB2395666A patent/GB1145334A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR1481592A (cs) | 1967-08-18 |
| DK123523B (da) | 1972-07-03 |
| DE1518829A1 (de) | 1969-11-13 |
| DE1518829C3 (de) | 1974-01-31 |
| CH475223A (de) | 1969-07-15 |
| DE1518829B2 (de) | 1973-07-05 |
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