GB1142143A - Piperidine-butyrophenones and a process for their production - Google Patents
Piperidine-butyrophenones and a process for their productionInfo
- Publication number
- GB1142143A GB1142143A GB12449/65A GB1244965A GB1142143A GB 1142143 A GB1142143 A GB 1142143A GB 12449/65 A GB12449/65 A GB 12449/65A GB 1244965 A GB1244965 A GB 1244965A GB 1142143 A GB1142143 A GB 1142143A
- Authority
- GB
- United Kingdom
- Prior art keywords
- piperidine derivatives
- butyrophenones
- halogeno
- march
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WLTFPYVGECWXFO-UHFFFAOYSA-N 1-phenyl-4-piperidin-1-ylbutan-1-one Chemical class C=1C=CC=CC=1C(=O)CCCN1CCCCC1 WLTFPYVGECWXFO-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000003053 piperidines Chemical class 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229960005015 local anesthetics Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Supports Or Holders For Household Use (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB12449/65A GB1142143A (en) | 1965-03-24 | 1965-03-24 | Piperidine-butyrophenones and a process for their production |
| SE03507/66A SE332984B (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-16 | |
| NO162139A NO122526B (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-16 | |
| CH393566A CH492705A (de) | 1965-03-24 | 1966-03-18 | Verfahren zur Herstellung pharmakologisch wirksamer Ketone |
| FI660714A FI47764C (fi) | 1965-03-24 | 1966-03-21 | Menetelmä -(4-alkyylipiperidiino)-p-F-butyrofenonien valmistamiseksi, joilla on farmakologisesti arvokkaita ominaisuuksia. |
| DE1645901A DE1645901C3 (de) | 1965-03-24 | 1966-03-22 | gamma-(4-Alkylp!peridino)-p-fluorbutyrophenone und Verfahren zu ihrer Herstellung |
| ES0324502A ES324502A1 (es) | 1965-03-24 | 1966-03-22 | Procedimiento para la preparacion de butirofenonas basicas. |
| FR54694A FR5474M (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-23 | |
| DK151366AA DK117829B (da) | 1965-03-24 | 1966-03-23 | Fremgangsmåde til fremstilling af basiske ketoner eller syreadditionssalte deraf. |
| FR54696A FR1497477A (fr) | 1965-03-24 | 1966-03-23 | Procédé pour la préparation de cétones basiques |
| NL6603799A NL6603799A (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-23 | |
| LU50735A LU50735A1 (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-23 | |
| BE678362D BE678362A (enrdf_load_stackoverflow) | 1965-03-24 | 1966-03-24 | |
| BE683543D BE683543A (enrdf_load_stackoverflow) | 1965-03-24 | 1966-07-01 | |
| US00078289A US3816433A (en) | 1965-03-24 | 1970-10-05 | 4-fluoro-ypsilon-(4-methylpiperidino)-butyrophenone and its pharmaceutically acceptable salts |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB12449/65A GB1142143A (en) | 1965-03-24 | 1965-03-24 | Piperidine-butyrophenones and a process for their production |
| US00078289A US3816433A (en) | 1965-03-24 | 1970-10-05 | 4-fluoro-ypsilon-(4-methylpiperidino)-butyrophenone and its pharmaceutically acceptable salts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1142143A true GB1142143A (en) | 1969-02-05 |
Family
ID=26249030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB12449/65A Expired GB1142143A (en) | 1965-03-24 | 1965-03-24 | Piperidine-butyrophenones and a process for their production |
Country Status (11)
| Country | Link |
|---|---|
| BE (2) | BE678362A (enrdf_load_stackoverflow) |
| CH (1) | CH492705A (enrdf_load_stackoverflow) |
| DE (1) | DE1645901C3 (enrdf_load_stackoverflow) |
| DK (1) | DK117829B (enrdf_load_stackoverflow) |
| FI (1) | FI47764C (enrdf_load_stackoverflow) |
| FR (2) | FR5474M (enrdf_load_stackoverflow) |
| GB (1) | GB1142143A (enrdf_load_stackoverflow) |
| LU (1) | LU50735A1 (enrdf_load_stackoverflow) |
| NL (1) | NL6603799A (enrdf_load_stackoverflow) |
| NO (1) | NO122526B (enrdf_load_stackoverflow) |
| SE (1) | SE332984B (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4344952A (en) | 1980-05-30 | 1982-08-17 | Ab Ferrosan | Method of treating diarrhoea with gamma-piperidino-butyrophenones |
| US6528529B1 (en) | 1998-03-31 | 2003-03-04 | Acadia Pharmaceuticals Inc. | Compounds with activity on muscarinic receptors |
-
1965
- 1965-03-24 GB GB12449/65A patent/GB1142143A/en not_active Expired
-
1966
- 1966-03-16 NO NO162139A patent/NO122526B/no unknown
- 1966-03-16 SE SE03507/66A patent/SE332984B/xx unknown
- 1966-03-18 CH CH393566A patent/CH492705A/de not_active IP Right Cessation
- 1966-03-21 FI FI660714A patent/FI47764C/fi active
- 1966-03-22 DE DE1645901A patent/DE1645901C3/de not_active Expired
- 1966-03-23 FR FR54694A patent/FR5474M/fr not_active Expired
- 1966-03-23 LU LU50735A patent/LU50735A1/xx unknown
- 1966-03-23 NL NL6603799A patent/NL6603799A/xx unknown
- 1966-03-23 DK DK151366AA patent/DK117829B/da unknown
- 1966-03-23 FR FR54696A patent/FR1497477A/fr not_active Expired
- 1966-03-24 BE BE678362D patent/BE678362A/xx not_active IP Right Cessation
- 1966-07-01 BE BE683543D patent/BE683543A/xx unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4344952A (en) | 1980-05-30 | 1982-08-17 | Ab Ferrosan | Method of treating diarrhoea with gamma-piperidino-butyrophenones |
| EP0041493B1 (en) * | 1980-05-30 | 1987-03-04 | AB Ferrosan | Use of gamma-piperidino-butyrophenones for the preparation of medicaments for treating diarrhoea |
| US6528529B1 (en) | 1998-03-31 | 2003-03-04 | Acadia Pharmaceuticals Inc. | Compounds with activity on muscarinic receptors |
| US7485651B2 (en) | 1998-03-31 | 2009-02-03 | Acadia Pharmaceuticals, Inc. | Compounds with activity on muscarinic receptors |
Also Published As
| Publication number | Publication date |
|---|---|
| SE332984B (enrdf_load_stackoverflow) | 1971-03-01 |
| DE1645901A1 (de) | 1970-07-16 |
| FI47764C (fi) | 1974-03-11 |
| FR5474M (enrdf_load_stackoverflow) | 1967-10-23 |
| CH492705A (de) | 1970-06-30 |
| DK117829B (da) | 1970-06-08 |
| FI47764B (enrdf_load_stackoverflow) | 1973-11-30 |
| BE683543A (enrdf_load_stackoverflow) | 1966-12-16 |
| NO122526B (enrdf_load_stackoverflow) | 1971-07-12 |
| DE1645901C3 (de) | 1975-01-30 |
| DE1645901B2 (de) | 1974-06-12 |
| LU50735A1 (enrdf_load_stackoverflow) | 1966-05-23 |
| BE678362A (enrdf_load_stackoverflow) | 1966-09-01 |
| FR1497477A (fr) | 1967-10-13 |
| NL6603799A (enrdf_load_stackoverflow) | 1966-09-26 |
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