GB1141470A - Steroid spiro-diaziprines and-diazirdines - Google Patents
Steroid spiro-diaziprines and-diazirdinesInfo
- Publication number
- GB1141470A GB1141470A GB18704/65A GB1870465A GB1141470A GB 1141470 A GB1141470 A GB 1141470A GB 18704/65 A GB18704/65 A GB 18704/65A GB 1870465 A GB1870465 A GB 1870465A GB 1141470 A GB1141470 A GB 1141470A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroid
- ring
- imino
- diaziridines
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003431 steroids Chemical class 0.000 title abstract 4
- 125000001841 imino group Chemical group [H]N=* 0.000 abstract 3
- YXHKONLOYHBTNS-UHFFFAOYSA-N Diazomethane Chemical group C=[N+]=[N-] YXHKONLOYHBTNS-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- -1 organomagnesium halide Chemical class 0.000 abstract 2
- 230000003647 oxidation Effects 0.000 abstract 2
- 238000007254 oxidation reaction Methods 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 229930194542 Keto Natural products 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- DQPBABKTKYNPMH-UHFFFAOYSA-N amino hydrogen sulfate Chemical compound NOS(O)(=O)=O DQPBABKTKYNPMH-UHFFFAOYSA-N 0.000 abstract 1
- 230000001195 anabolic effect Effects 0.000 abstract 1
- 230000002280 anti-androgenic effect Effects 0.000 abstract 1
- 230000000380 anti-gestagenic effect Effects 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- DIXBSCZRIZDQGC-UHFFFAOYSA-N diaziridine Chemical group C1NN1 DIXBSCZRIZDQGC-UHFFFAOYSA-N 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 238000005907 ketalization reaction Methods 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 150000002900 organolithium compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB18704/65A GB1141470A (en) | 1965-05-04 | 1965-05-04 | Steroid spiro-diaziprines and-diazirdines |
| NL6605966A NL6605966A (enrdf_load_stackoverflow) | 1965-05-04 | 1966-05-03 | |
| FR60056A FR1483982A (fr) | 1965-05-04 | 1966-05-03 | Procédé de fabrication de dérivés stéroïdes |
| DE19661593151 DE1593151A1 (de) | 1965-05-04 | 1966-05-03 | Verfahren zur Herstellung von 17-Spiro-3'-diazirin- und -diaziridin-Steroiden |
| AT04188/66A AT281308B (de) | 1965-05-04 | 1966-05-03 | Verfahren zur herstellung neuer steroide |
| SE605266A SE330694B (enrdf_load_stackoverflow) | 1965-05-04 | 1966-05-03 | |
| BE680513D BE680513A (enrdf_load_stackoverflow) | 1965-05-04 | 1966-05-04 | |
| DK227166A DK123409B (da) | 1965-05-04 | 1966-05-04 | Fremgangsmåde til fremstilling af 17-spiro-3'-diaziridin- eller -diazirinsteroider af androstan-, gonan- eller estranrækken. |
| FR71950A FR6860M (enrdf_load_stackoverflow) | 1965-05-04 | 1966-08-03 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB18704/65A GB1141470A (en) | 1965-05-04 | 1965-05-04 | Steroid spiro-diaziprines and-diazirdines |
| GB2207365 | 1965-05-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1141470A true GB1141470A (en) | 1969-01-29 |
Family
ID=26253556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB18704/65A Expired GB1141470A (en) | 1965-05-04 | 1965-05-04 | Steroid spiro-diaziprines and-diazirdines |
Country Status (8)
| Country | Link |
|---|---|
| AT (1) | AT281308B (enrdf_load_stackoverflow) |
| BE (1) | BE680513A (enrdf_load_stackoverflow) |
| DE (1) | DE1593151A1 (enrdf_load_stackoverflow) |
| DK (1) | DK123409B (enrdf_load_stackoverflow) |
| FR (1) | FR6860M (enrdf_load_stackoverflow) |
| GB (1) | GB1141470A (enrdf_load_stackoverflow) |
| NL (1) | NL6605966A (enrdf_load_stackoverflow) |
| SE (1) | SE330694B (enrdf_load_stackoverflow) |
-
1965
- 1965-05-04 GB GB18704/65A patent/GB1141470A/en not_active Expired
-
1966
- 1966-05-03 SE SE605266A patent/SE330694B/xx unknown
- 1966-05-03 NL NL6605966A patent/NL6605966A/xx unknown
- 1966-05-03 DE DE19661593151 patent/DE1593151A1/de active Pending
- 1966-05-03 AT AT04188/66A patent/AT281308B/de not_active IP Right Cessation
- 1966-05-04 DK DK227166A patent/DK123409B/da unknown
- 1966-05-04 BE BE680513D patent/BE680513A/xx unknown
- 1966-08-03 FR FR71950A patent/FR6860M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR6860M (enrdf_load_stackoverflow) | 1969-04-14 |
| AT281308B (de) | 1970-05-25 |
| NL6605966A (enrdf_load_stackoverflow) | 1966-11-07 |
| SE330694B (enrdf_load_stackoverflow) | 1970-11-30 |
| BE680513A (enrdf_load_stackoverflow) | 1966-11-04 |
| DK123409B (da) | 1972-06-19 |
| DE1593151A1 (de) | 1970-07-23 |
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