GB1131847A - Cyclic and non-cyclic amidines and process for their preparation - Google Patents
Cyclic and non-cyclic amidines and process for their preparationInfo
- Publication number
- GB1131847A GB1131847A GB5185466A GB5185466A GB1131847A GB 1131847 A GB1131847 A GB 1131847A GB 5185466 A GB5185466 A GB 5185466A GB 5185466 A GB5185466 A GB 5185466A GB 1131847 A GB1131847 A GB 1131847A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- prepared
- vinyline
- ethylene
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 cyclic amidines Chemical class 0.000 title abstract 3
- 125000004122 cyclic group Chemical group 0.000 title abstract 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 4
- 239000005977 Ethylene Substances 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- MLIREBYILWEBDM-UHFFFAOYSA-N cyanoacetic acid Chemical compound OC(=O)CC#N MLIREBYILWEBDM-UHFFFAOYSA-N 0.000 abstract 2
- HYBBIBNJHNGZAN-UHFFFAOYSA-N furfural Chemical compound O=CC1=CC=CO1 HYBBIBNJHNGZAN-UHFFFAOYSA-N 0.000 abstract 2
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 2
- XSVYCXHKWNFZLL-ONEGZZNKSA-N (e)-3-(furan-2-yl)prop-2-enamide Chemical compound NC(=O)\C=C\C1=CC=CO1 XSVYCXHKWNFZLL-ONEGZZNKSA-N 0.000 abstract 1
- FSSPGSAQUIYDCN-UHFFFAOYSA-N 1,3-Propane sultone Chemical compound O=S1(=O)CCCO1 FSSPGSAQUIYDCN-UHFFFAOYSA-N 0.000 abstract 1
- SPACFHUHWJAHGC-UHFFFAOYSA-N 3-(3-methylfuran-2-yl)prop-2-enamide Chemical compound CC1=C(OC=C1)C=CC(=O)N SPACFHUHWJAHGC-UHFFFAOYSA-N 0.000 abstract 1
- ZFHDAORLRLTYGP-UHFFFAOYSA-N 3-(3-methylfuran-2-yl)prop-2-enenitrile Chemical compound CC=1C=COC=1C=CC#N ZFHDAORLRLTYGP-UHFFFAOYSA-N 0.000 abstract 1
- DSMRYCOTKWYTRF-UHFFFAOYSA-N 3-methylfuran-2-carbaldehyde Chemical compound CC=1C=COC=1C=O DSMRYCOTKWYTRF-UHFFFAOYSA-N 0.000 abstract 1
- USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 abstract 1
- 239000005695 Ammonium acetate Substances 0.000 abstract 1
- 150000008360 acrylonitriles Chemical class 0.000 abstract 1
- 238000006136 alcoholysis reaction Methods 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 229940043376 ammonium acetate Drugs 0.000 abstract 1
- 235000019257 ammonium acetate Nutrition 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 abstract 1
- KUQZZRZZFKMDIN-UHFFFAOYSA-N ethyl 3-(furan-2-yl)propanimidate hydrochloride Chemical compound Cl.O1C(=CC=C1)CCC(OCC)=N KUQZZRZZFKMDIN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51782765A | 1965-12-30 | 1965-12-30 | |
| US56910866A | 1966-08-01 | 1966-08-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1131847A true GB1131847A (en) | 1968-10-30 |
Family
ID=27059245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5185466A Expired GB1131847A (en) | 1965-12-30 | 1966-11-18 | Cyclic and non-cyclic amidines and process for their preparation |
Country Status (10)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001098262A1 (en) * | 2000-06-23 | 2001-12-27 | Merck Sharp & Dohme Limited | Amidine derivatives as selective antagonists of nmda receptors |
-
1966
- 1966-11-16 IL IL2687066A patent/IL26870A/en unknown
- 1966-11-18 GB GB5185466A patent/GB1131847A/en not_active Expired
- 1966-12-07 FR FR86565A patent/FR1510102A/fr not_active Expired
- 1966-12-09 BR BR18523866A patent/BR6685238D0/pt unknown
- 1966-12-12 BE BE691029D patent/BE691029A/xx not_active IP Right Cessation
- 1966-12-19 ES ES334659A patent/ES334659A1/es not_active Expired
- 1966-12-22 DE DE19661620145 patent/DE1620145A1/de active Pending
- 1966-12-22 NL NL6617999A patent/NL139312B/xx not_active IP Right Cessation
- 1966-12-23 CH CH1843666A patent/CH491114A/de not_active IP Right Cessation
- 1966-12-23 JP JP8391466A patent/JPS4916428B1/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001098262A1 (en) * | 2000-06-23 | 2001-12-27 | Merck Sharp & Dohme Limited | Amidine derivatives as selective antagonists of nmda receptors |
| AU2001264116B2 (en) * | 2000-06-23 | 2006-04-13 | Merck Sharp & Dohme Limited | Amidine derivatives as selective antagonists of NMDA receptors |
Also Published As
| Publication number | Publication date |
|---|---|
| IL26870A (en) | 1971-01-28 |
| JPS4916428B1 (enrdf_load_stackoverflow) | 1974-04-22 |
| NL6617999A (enrdf_load_stackoverflow) | 1967-07-03 |
| FR1510102A (fr) | 1968-01-19 |
| BE691029A (enrdf_load_stackoverflow) | 1967-06-12 |
| DE1620145A1 (de) | 1970-03-12 |
| NL139312B (nl) | 1973-07-16 |
| CH491114A (de) | 1970-05-31 |
| ES334659A1 (es) | 1969-08-16 |
| BR6685238D0 (pt) | 1973-10-25 |
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