GB1128325A - Improvements in water-in-oil emulsion vaccines - Google Patents

Improvements in water-in-oil emulsion vaccines

Info

Publication number
GB1128325A
GB1128325A GB4591164A GB4591164A GB1128325A GB 1128325 A GB1128325 A GB 1128325A GB 4591164 A GB4591164 A GB 4591164A GB 4591164 A GB4591164 A GB 4591164A GB 1128325 A GB1128325 A GB 1128325A
Authority
GB
United Kingdom
Prior art keywords
vaccine
water
oil emulsion
oil
phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4591164A
Inventor
Robert Orrock Thomson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB4591164A priority Critical patent/GB1128325A/en
Priority to IL2455565A priority patent/IL24555A/en
Priority to DE19651492255 priority patent/DE1492255A1/en
Priority to BE672177D priority patent/BE672177A/xx
Priority to ES0319427A priority patent/ES319427A1/en
Priority to BR17476165A priority patent/BR6574761D0/en
Priority to NL6514661A priority patent/NL6514661A/xx
Publication of GB1128325A publication Critical patent/GB1128325A/en
Priority to MY7100149A priority patent/MY7100149A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Abstract

1,128,325. Vaccines. WELLCOME FOUNDATION Ltd. 5 Nov., 1965 [11 Nov., 1964], No. 45911/64. Heading A5B. A water-in-oil emulsion vaccine comprises a continuous oil phase, an aqueous, antigencontaining phase constituting less than 20% by volume of the vaccine and' an emulsifier in a quantity not less than half but at least 1/10th of the volume of the aqueous phase. The vaccine may be a clostridial vaccine e.g. Cl. tetani, Cl. perfringens, &c. or Br. abortus. The emulsifier may be a non-ionic surfactant and the oil may be a mineral oil.
GB4591164A 1964-11-11 1964-11-11 Improvements in water-in-oil emulsion vaccines Expired GB1128325A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GB4591164A GB1128325A (en) 1964-11-11 1964-11-11 Improvements in water-in-oil emulsion vaccines
IL2455565A IL24555A (en) 1964-11-11 1965-11-03 Water-in-oil emulsion vaccines
DE19651492255 DE1492255A1 (en) 1964-11-11 1965-11-09 Immunization preparation
BE672177D BE672177A (en) 1964-11-11 1965-11-10
ES0319427A ES319427A1 (en) 1964-11-11 1965-11-10 Improvements in water-in-oil emulsion vaccines
BR17476165A BR6574761D0 (en) 1964-11-11 1965-11-11 PROCESS FOR THE PREPARATION OF NEW VACCINES
NL6514661A NL6514661A (en) 1964-11-11 1965-11-11
MY7100149A MY7100149A (en) 1964-11-11 1971-12-31 Improvements in water-in-oil emulsion vaccines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4591164A GB1128325A (en) 1964-11-11 1964-11-11 Improvements in water-in-oil emulsion vaccines

Publications (1)

Publication Number Publication Date
GB1128325A true GB1128325A (en) 1968-09-25

Family

ID=10439065

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4591164A Expired GB1128325A (en) 1964-11-11 1964-11-11 Improvements in water-in-oil emulsion vaccines

Country Status (8)

Country Link
BE (1) BE672177A (en)
BR (1) BR6574761D0 (en)
DE (1) DE1492255A1 (en)
ES (1) ES319427A1 (en)
GB (1) GB1128325A (en)
IL (1) IL24555A (en)
MY (1) MY7100149A (en)
NL (1) NL6514661A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0187286A1 (en) * 1984-12-20 1986-07-16 BEHRINGWERKE Aktiengesellschaft Oil-adjuvated vaccine and its manufacturing process
WO1998027964A1 (en) * 1996-12-24 1998-07-02 Fort Dodge Australia Pty. Limited Veterinary vaccines
WO1999020305A1 (en) 1997-10-17 1999-04-29 Fort Dodge Australia Pty. Limited Veterinary vaccines
US6524592B2 (en) 1997-10-17 2003-02-25 American Home Products Corporation Veterinary vaccines

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035795A1 (en) * 1969-03-31 1970-12-24 Merieux Inst Anti-brucellosis vaccine prepn
FR2702373B1 (en) * 1993-03-08 1996-06-07 Rhone Merieux Water-in-oil fluid vaccine emulsions containing a metabolizable oil.
FR2702374B1 (en) * 1993-03-08 1995-04-14 Rhone Merieux Water-in-oil fluid vaccine emulsions containing a metabolizable oil.

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0187286A1 (en) * 1984-12-20 1986-07-16 BEHRINGWERKE Aktiengesellschaft Oil-adjuvated vaccine and its manufacturing process
WO1998027964A1 (en) * 1996-12-24 1998-07-02 Fort Dodge Australia Pty. Limited Veterinary vaccines
WO1999020305A1 (en) 1997-10-17 1999-04-29 Fort Dodge Australia Pty. Limited Veterinary vaccines
EP1023083A1 (en) * 1997-10-17 2000-08-02 Fort Dodge Australia Pty. Limited Veterinary vaccines
AU753804B2 (en) * 1997-10-17 2002-10-31 Zoetis Services Llc Veterinary vaccines
US6524592B2 (en) 1997-10-17 2003-02-25 American Home Products Corporation Veterinary vaccines
EP1023083A4 (en) * 1997-10-17 2006-06-14 Wyeth Corp Veterinary vaccines

Also Published As

Publication number Publication date
MY7100149A (en) 1971-12-31
NL6514661A (en) 1966-05-12
BR6574761D0 (en) 1973-08-02
IL24555A (en) 1969-07-30
BE672177A (en) 1966-05-10
ES319427A1 (en) 1966-04-16
DE1492255A1 (en) 1969-11-06

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