GB1126245A - Indole derivatives - Google Patents

Indole derivatives

Info

Publication number
GB1126245A
GB1126245A GB53572/66A GB5357266A GB1126245A GB 1126245 A GB1126245 A GB 1126245A GB 53572/66 A GB53572/66 A GB 53572/66A GB 5357266 A GB5357266 A GB 5357266A GB 1126245 A GB1126245 A GB 1126245A
Authority
GB
United Kingdom
Prior art keywords
indole
prepared
lower alkyl
substituted
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB53572/66A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of GB1126245A publication Critical patent/GB1126245A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
GB53572/66A 1965-12-03 1966-11-30 Indole derivatives Expired GB1126245A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US51136265A 1965-12-03 1965-12-03
US51135865A 1965-12-03 1965-12-03
US51131165A 1965-12-03 1965-12-03
US51800766A 1966-01-03 1966-01-03
US51136266A 1966-01-03 1966-01-03
US84471769A 1969-06-26 1969-06-26

Publications (1)

Publication Number Publication Date
GB1126245A true GB1126245A (en) 1968-09-05

Family

ID=27560085

Family Applications (1)

Application Number Title Priority Date Filing Date
GB53572/66A Expired GB1126245A (en) 1965-12-03 1966-11-30 Indole derivatives

Country Status (10)

Country Link
US (5) US3445472A (en:Method)
BE (1) BE690550A (en:Method)
BR (1) BR6685067D0 (en:Method)
CH (1) CH510683A (en:Method)
DE (1) DE1645942A1 (en:Method)
FR (2) FR6291M (en:Method)
GB (1) GB1126245A (en:Method)
IL (1) IL26969A (en:Method)
NL (1) NL6616947A (en:Method)
SE (1) SE328286B (en:Method)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064255A (en) 1975-12-12 1977-12-20 Mar-Pha Societe D'etudes Et D'exploitation De Marques Compositions containing new indole derivatives and their use in pharmacology
US6573262B2 (en) 2000-07-10 2003-06-03 Bristol-Myers Sqibb Company Composition and antiviral activity of substituted indoleoxoacetic piperazine derivatives
EP0699194B1 (en) * 1993-05-22 2006-11-29 SmithKline Beecham plc 5-ht4 receptor antagonists

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
US3696104A (en) * 1970-04-27 1972-10-03 Robins Co Inc A H 1-hydrocarbon-4-aryl-2,3-dioxo-5-(2-haloethyl) piperazines
US4160862A (en) * 1972-06-12 1979-07-10 Sterling Drug Inc. 1-Acyl-3-(amino-lower-alkyl)indoles
US3947578A (en) * 1972-07-28 1976-03-30 Roussel Uclaf Omega-[4-(3"-indolyl)-piperidino]-alkyl-arylketones as nevroleptics
FR2193584B1 (en:Method) * 1972-07-28 1975-08-08 Roussel Uclaf
GB1498884A (en) * 1975-04-15 1978-01-25 Wyeth John & Brother Ltd Aminoacetamide-pyridyl-tetrahydropyridyl and-piperidyl derivatives
US4132792A (en) * 1977-12-19 1979-01-02 Warner-Lambert Bis(2-[(disubstituted amino)methyl]-1H-indole) compounds
FR2506310A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((alkyl- et alcenyl-3 piperidyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments
FR2506311A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((piperidyl-4)-2 alkyl-1 ethyl)-3 indoles et leur utilisation comme medicaments
FR2506309A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((tetra- et hexahydro pyridyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments
CS229934B2 (en) * 1981-07-07 1984-07-16 Pfizer Production method subst.indolylacryte acid derivative
US4895844A (en) * 1987-03-25 1990-01-23 Harbor Branch Oceanographic Institution, Inc. Indole alkaloid compositions and their methods of use
US5068234A (en) * 1990-02-26 1991-11-26 Sterling Drug Inc. 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles
US5965582A (en) * 1994-08-03 1999-10-12 Asta Medica Aktiengesellschaft N-benzylindole and benzopyrazole derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunemodulating effect
CN114591295B (zh) * 2022-03-04 2023-11-07 贵州大学 含吡啶盐的n-(吲哚酰基)-n’-(取代的)的丙基酰肼类衍生物、其制备方法及应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2909523A (en) * 1957-10-11 1959-10-20 American Cyanamid Co Substituted piperazines and method of preparing the same
US2930797A (en) * 1957-11-22 1960-03-29 Upjohn Co 2-alkyl-3-indoleglyoxylamides
US3030363A (en) * 1959-06-10 1962-04-17 Boehringer Sohn Ingelheim Derivatives of xanthine
GB944443A (en:Method) * 1959-09-25 1900-01-01
US3136770A (en) * 1960-04-01 1964-06-09 Neisler Lab Inc Indolyl substituted piperidines
US3198798A (en) * 1962-11-02 1965-08-03 Sterling Drug Inc Phthalimido- and isoindolinyl-alkylpiperazines and their preparation
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
FR1461641A (fr) * 1964-11-11 1966-02-25 Ciba Geigy Nouveaux indoles et procédé pour leur préparation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064255A (en) 1975-12-12 1977-12-20 Mar-Pha Societe D'etudes Et D'exploitation De Marques Compositions containing new indole derivatives and their use in pharmacology
EP0699194B1 (en) * 1993-05-22 2006-11-29 SmithKline Beecham plc 5-ht4 receptor antagonists
US6573262B2 (en) 2000-07-10 2003-06-03 Bristol-Myers Sqibb Company Composition and antiviral activity of substituted indoleoxoacetic piperazine derivatives

Also Published As

Publication number Publication date
FR1510003A (fr) 1968-01-19
US3462441A (en) 1969-08-19
DE1645942A1 (de) 1970-10-22
US3471499A (en) 1969-10-07
FR6291M (en:Method) 1968-09-09
US3462440A (en) 1969-08-19
BR6685067D0 (pt) 1973-12-26
SE328286B (en:Method) 1970-09-14
NL6616947A (en:Method) 1967-06-05
CH510683A (de) 1971-07-31
US3577423A (en) 1971-05-04
BE690550A (en:Method) 1967-06-01
US3445472A (en) 1969-05-20
IL26969A (en) 1970-12-24

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