GB1123853A - New hydroxocobalamine derivatives - Google Patents
New hydroxocobalamine derivativesInfo
- Publication number
- GB1123853A GB1123853A GB6305/67A GB630567A GB1123853A GB 1123853 A GB1123853 A GB 1123853A GB 6305/67 A GB6305/67 A GB 6305/67A GB 630567 A GB630567 A GB 630567A GB 1123853 A GB1123853 A GB 1123853A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxocobalamine
- derivatives
- iodo
- derived
- stimulate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YOZNUFWCRFCGIH-BYFNXCQMSA-L hydroxocobalamin Chemical class O[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O YOZNUFWCRFCGIH-BYFNXCQMSA-L 0.000 title abstract 5
- 235000004867 hydroxocobalamin Nutrition 0.000 abstract 3
- 239000011704 hydroxocobalamin Substances 0.000 abstract 3
- NYPYHUZRZVSYKL-ZETCQYMHSA-N 3,5-diiodo-L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC(I)=C(O)C(I)=C1 NYPYHUZRZVSYKL-ZETCQYMHSA-N 0.000 abstract 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 239000003826 tablet Substances 0.000 abstract 2
- 229920002472 Starch Polymers 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
- 239000012062 aqueous buffer Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000035604 cholesterolaemia Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 229920001592 potato starch Polymers 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 229940100445 wheat starch Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR49062A FR5372M (forum.php) | 1966-02-10 | 1966-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1123853A true GB1123853A (en) | 1968-08-14 |
Family
ID=8600993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6305/67A Expired GB1123853A (en) | 1966-02-10 | 1967-02-09 | New hydroxocobalamine derivatives |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3459855A (forum.php) |
| BE (1) | BE693038A (forum.php) |
| CH (1) | CH471139A (forum.php) |
| DE (1) | DE1695357A1 (forum.php) |
| FI (1) | FI47191C (forum.php) |
| FR (1) | FR5372M (forum.php) |
| GB (1) | GB1123853A (forum.php) |
| LU (1) | LU52920A1 (forum.php) |
| NL (1) | NL6701970A (forum.php) |
| SE (1) | SE333934B (forum.php) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0069450A1 (en) * | 1981-06-22 | 1983-01-12 | TECHNICON INSTRUMENTS CORPORATION (a New York corporation) | Labelled vitamin B12 derivatives, their preparation and use |
| EP0220030A3 (en) * | 1985-10-10 | 1987-09-30 | Biotechnology Australia Pty. Ltd. | Oral delivery system |
| US5807832A (en) * | 1987-06-09 | 1998-09-15 | Biotech Australia Pty Limited | Oral delivery of biologically active substances bound to vitamin B12 |
| US6159502A (en) * | 1991-04-02 | 2000-12-12 | Biotech Australia Pty Ltd | Oral delivery systems for microparticles |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3624303A (en) * | 1970-03-09 | 1971-11-30 | Motorola Inc | Signal-demodulating phase control system |
| US3981863A (en) * | 1975-02-25 | 1976-09-21 | Micromedic Diagonistics, Inc. | Cyanocobalamin derivatives |
| US4209614A (en) * | 1978-05-30 | 1980-06-24 | E. R. Squibb & Sons, Inc. | Vitamin B12 derivative suitable for radiolabeling |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2748054A (en) * | 1951-10-16 | 1956-05-29 | Olin Mathieson | Stable vitamin b12 and soluble folic acid salt mixture |
| US3035983A (en) * | 1958-07-18 | 1962-05-22 | Distillers Co Yeast Ltd | Process for the production of cobalamin/peptide compositions |
| US3035974A (en) * | 1960-02-18 | 1962-05-22 | Israel Murray | Compositions and method for the parenteral administration of thyroxine |
-
1966
- 1966-02-10 FR FR49062A patent/FR5372M/fr not_active Expired
-
1967
- 1967-01-23 CH CH91367A patent/CH471139A/fr not_active IP Right Cessation
- 1967-01-23 BE BE693038D patent/BE693038A/xx unknown
- 1967-02-01 LU LU52920D patent/LU52920A1/xx unknown
- 1967-02-06 US US614138A patent/US3459855A/en not_active Expired - Lifetime
- 1967-02-08 SE SE01757/67A patent/SE333934B/xx unknown
- 1967-02-09 FI FI670383A patent/FI47191C/fi active
- 1967-02-09 NL NL6701970A patent/NL6701970A/xx unknown
- 1967-02-09 GB GB6305/67A patent/GB1123853A/en not_active Expired
- 1967-02-10 DE DE19671695357 patent/DE1695357A1/de active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0069450A1 (en) * | 1981-06-22 | 1983-01-12 | TECHNICON INSTRUMENTS CORPORATION (a New York corporation) | Labelled vitamin B12 derivatives, their preparation and use |
| EP0220030A3 (en) * | 1985-10-10 | 1987-09-30 | Biotechnology Australia Pty. Ltd. | Oral delivery system |
| US5428023A (en) * | 1985-10-10 | 1995-06-27 | Biotechnology Australia Pty. Ltd. | Oral delivery of biologically active substances bound to vitamin B12 or analogues thereof |
| US5589463A (en) * | 1985-10-10 | 1996-12-31 | Biotechnology Autralia Pty., Ltd. | Oral delivery of biologically active substances bound to vitamin B12 |
| US5807832A (en) * | 1987-06-09 | 1998-09-15 | Biotech Australia Pty Limited | Oral delivery of biologically active substances bound to vitamin B12 |
| US6159502A (en) * | 1991-04-02 | 2000-12-12 | Biotech Australia Pty Ltd | Oral delivery systems for microparticles |
Also Published As
| Publication number | Publication date |
|---|---|
| BE693038A (forum.php) | 1967-07-03 |
| NL6701970A (forum.php) | 1967-08-11 |
| US3459855A (en) | 1969-08-05 |
| FR5372M (forum.php) | 1967-10-16 |
| SE333934B (forum.php) | 1971-04-05 |
| DE1695357A1 (de) | 1972-02-24 |
| FI47191B (forum.php) | 1973-07-02 |
| LU52920A1 (forum.php) | 1967-04-03 |
| CH471139A (fr) | 1969-04-15 |
| FI47191C (fi) | 1973-10-10 |
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