GB1119543A - Antigen preparation and vaccine - Google Patents
Antigen preparation and vaccineInfo
- Publication number
- GB1119543A GB1119543A GB150466A GB150466A GB1119543A GB 1119543 A GB1119543 A GB 1119543A GB 150466 A GB150466 A GB 150466A GB 150466 A GB150466 A GB 150466A GB 1119543 A GB1119543 A GB 1119543A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pertussis
- antigen
- concentration
- mixture
- cell wall
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000427 antigen Substances 0.000 title abstract 6
- 102000036639 antigens Human genes 0.000 title abstract 6
- 108091007433 antigens Proteins 0.000 title abstract 6
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 241000588832 Bordetella pertussis Species 0.000 abstract 5
- 239000000463 material Substances 0.000 abstract 4
- 210000004027 cell Anatomy 0.000 abstract 3
- 210000002421 cell wall Anatomy 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 2
- 229940037003 alum Drugs 0.000 abstract 2
- 239000007900 aqueous suspension Substances 0.000 abstract 2
- 238000000605 extraction Methods 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 201000005702 Pertussis Diseases 0.000 abstract 1
- 101710194807 Protective antigen Proteins 0.000 abstract 1
- 206010043376 Tetanus Diseases 0.000 abstract 1
- 239000002156 adsorbate Substances 0.000 abstract 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 abstract 1
- 229910021502 aluminium hydroxide Inorganic materials 0.000 abstract 1
- ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 abstract 1
- 229940001007 aluminium phosphate Drugs 0.000 abstract 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 230000006837 decompression Effects 0.000 abstract 1
- 206010013023 diphtheria Diseases 0.000 abstract 1
- 239000002360 explosive Substances 0.000 abstract 1
- 229940031348 multivalent vaccine Drugs 0.000 abstract 1
- 239000008363 phosphate buffer Substances 0.000 abstract 1
- 239000002504 physiological saline solution Substances 0.000 abstract 1
- 235000011164 potassium chloride Nutrition 0.000 abstract 1
- 239000001103 potassium chloride Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M sodium chloride Inorganic materials [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 abstract 1
- 229940033663 thimerosal Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42669165A | 1965-01-19 | 1965-01-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1119543A true GB1119543A (en) | 1968-07-10 |
Family
ID=23691819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB150466A Expired GB1119543A (en) | 1965-01-19 | 1966-01-12 | Antigen preparation and vaccine |
Country Status (11)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2845745A1 (de) * | 1977-10-28 | 1979-05-10 | American Cyanamid Co | Kombinationsvaccine |
| EP0080021A3 (en) * | 1981-11-19 | 1983-11-16 | American Cyanamid Company | Haemophilus influenzae type b and pertussis outer membrane component combined vaccine |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4338299A (en) * | 1980-11-17 | 1982-07-06 | Dso "Pharmachim" | Vaccine against pertussis |
| WO1998054987A1 (en) * | 1997-06-04 | 1998-12-10 | Cellular Improvements Ltd | Method and apparatus for disruption of biological material |
-
1966
- 1966-01-10 IL IL2494666A patent/IL24946A/en unknown
- 1966-01-10 NO NO16118766A patent/NO116869B/no unknown
- 1966-01-12 GB GB150466A patent/GB1119543A/en not_active Expired
- 1966-01-17 BR BR17647466A patent/BR6676474D0/pt unknown
- 1966-01-18 DE DE19661617605 patent/DE1617605C3/de not_active Expired
- 1966-01-18 DK DK26066A patent/DK115720B/da unknown
- 1966-01-18 ES ES0322331A patent/ES322331A1/es not_active Expired
- 1966-01-18 FR FR46281A patent/FR1475742A/fr not_active Expired
- 1966-01-18 SE SE00630/66A patent/SE326797B/xx unknown
- 1966-01-19 NL NL6600703A patent/NL6600703A/xx unknown
- 1966-01-19 BE BE675310D patent/BE675310A/xx unknown
- 1966-04-15 FR FR57878A patent/FR5550M/fr not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2845745A1 (de) * | 1977-10-28 | 1979-05-10 | American Cyanamid Co | Kombinationsvaccine |
| EP0080021A3 (en) * | 1981-11-19 | 1983-11-16 | American Cyanamid Company | Haemophilus influenzae type b and pertussis outer membrane component combined vaccine |
Also Published As
| Publication number | Publication date |
|---|---|
| BE675310A (enrdf_load_stackoverflow) | 1966-07-19 |
| NO116869B (enrdf_load_stackoverflow) | 1969-06-02 |
| DE1617605A1 (de) | 1971-04-01 |
| DK115720B (da) | 1969-11-03 |
| BR6676474D0 (pt) | 1973-09-11 |
| DE1617605C3 (de) | 1974-08-29 |
| DE1617605B2 (de) | 1974-01-31 |
| FR1475742A (fr) | 1967-04-07 |
| NL6600703A (enrdf_load_stackoverflow) | 1966-07-20 |
| IL24946A (en) | 1969-05-28 |
| FR5550M (enrdf_load_stackoverflow) | 1967-11-20 |
| SE326797B (enrdf_load_stackoverflow) | 1970-08-03 |
| ES322331A1 (es) | 1966-11-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Levine et al. | Attenuated, streptomycin-dependent Salmonella typhi oral vaccine: potential deleterious effects of lyophilization | |
| WO1980000412A1 (en) | Pasteurellosis vaccines | |
| Tacket et al. | Persistence of antibody titres three years after vaccination with Vi polysaccharide vaccine against typhoid fever | |
| Glode et al. | Comparative Immunogenicity of Vaccines Prepared from Capsular Polysaccharides of Group C Neisseria meningitidis O. Acetyl. Positive and O. Acetyl. Negative Variants and Escherichia coli K92 in Adult Volunteers | |
| GB1218277A (en) | Dry water-dispersible aluminium hydroxide gels | |
| Daniels et al. | Characterization of the Salmonella paratyphi C Vi polysaccharide | |
| Noll et al. | Preparation and biological properties of a chemically modified Escherichia coli endotoxin of high immunogenic potency and low toxicity | |
| GB1119543A (en) | Antigen preparation and vaccine | |
| US3395219A (en) | Process for production of pertussis antigen | |
| ES469225A1 (es) | Procedimiento para potenciar la accion de las vacunas. | |
| Morris et al. | The relationship of M protein and resistance to phagocytosis in the beta hemolytic streptococci | |
| US3465078A (en) | Method of recovering antigens from bordetella pertussis cells | |
| Lynn et al. | Immunoprotective activity of ribosomes from Haemophilus influenzae | |
| Dzata et al. | Immunopotentiation of cattle vaccinated with a soluble Brucella abortus antigen with low LPS content: an analysis of cellular and humoral immune responses | |
| US3577527A (en) | Neisseria meningitidis antigen | |
| Schmidt et al. | Immunodiffusion reactions with rubella antigens | |
| Chen et al. | Experimental comparison of the immunogenicity of antigens in the residue of ultrasonated avirulent Pasteurella pestis with a vaccine prepared with killed virulent whole organisms | |
| GB2227936A (en) | Vaccine against brucella abortus | |
| Landay et al. | Serological comparison of the three morphological phases of Coccidioides immitis by the agar gel diffusion method | |
| Tadayon et al. | The capacity of various fractions of Pasteurella haemolytica to stimulate protective immunity in mice and hamsters | |
| Gaines et al. | Studies on Infection and Immunity in Experimental Typhoid Fever: II. Susceptibility of Recovered Animals to Re-Exposure | |
| Nutter | Antigens of Pasteurella tularensis: preparative procedures | |
| IE35396L (en) | Producing bruncella vaccines. | |
| Foley et al. | Studies on the Biology of Cryptococcus: IV. Isolation of a Highly Polymerized Polysaccharide from Encapsulated Strains | |
| Cooper et al. | Immunogenicity of ribosomal preparations from Neisseria gonorrhoeae |